Stable gene transfer to muscle using non-integrating lentiviral vectors L Apolonia, SN Waddington, C Fernandes, NJ Ward, G Bouma, ... Molecular Therapy 15 (11), 1947-1954, 2007 | 233 | 2007 |
The Wiskott-Aldrich syndrome: the actin cytoskeleton and immune cell function MP Blundell, A Worth, G Bouma, AJ Thrasher Disease markers 29 (3-4), 157-175, 2010 | 144 | 2010 |
Increased serum levels of MRP-8/14 in type 1 diabetes induce an increased expression of CD11b and an enhanced adhesion of circulating monocytes to fibronectin G Bouma, WK Lam-Tse, AF Wierenga-Wolf, HA Drexhage, MA Versnel Diabetes 53 (8), 1979-1986, 2004 | 141 | 2004 |
Wiskott–Aldrich syndrome: immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation G Bouma, SO Burns, AJ Thrasher Immunobiology 214 (9-10), 778-790, 2009 | 139 | 2009 |
B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice M Recher, SO Burns, MA de la Fuente, S Volpi, C Dahlberg, JE Walter, ... Blood, The Journal of the American Society of Hematology 119 (12), 2819-2828, 2012 | 126 | 2012 |
Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis A Meyer-Bahlburg, S Becker-Herman, S Humblet-Baron, S Khim, ... Blood, The Journal of the American Society of Hematology 112 (10), 4158-4169, 2008 | 111 | 2008 |
Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells G Bouma, S Burns, AJ Thrasher Blood, The Journal of the American Society of Hematology 110 (13), 4278-4284, 2007 | 110 | 2007 |
Nonintegrating lentivector vaccines stimulate prolonged T-cell and antibody responses and are effective in tumor therapy K Karwacz, S Mukherjee, L Apolonia, MP Blundell, G Bouma, D Escors, ... Journal of Virology 83 (7), 3094-3103, 2009 | 101 | 2009 |
Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming G Bouma, A Mendoza-Naranjo, MP Blundell, E De Falco, KL Parsley, ... Blood, The Journal of the American Society of Hematology 118 (9), 2492-2501, 2011 | 97 | 2011 |
Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation A Mendoza-Naranjo, G Bouma, C Pereda, M Ramírez, KF Webb, ... The Journal of Immunology 187 (6), 3121-3132, 2011 | 94 | 2011 |
Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1 J Record, D Malinova, HL Zenner, V Plagnol, K Nowak, F Syed, G Bouma, ... Blood, The Journal of the American Society of Hematology 126 (13), 1527-1535, 2015 | 85 | 2015 |
Recent advances in the understanding of genetic defects of neutrophil number and function G Bouma, PJ Ancliff, AJ Thrasher, SO Burns British journal of haematology 151 (4), 312-326, 2010 | 84 | 2010 |
Phosphorylation of WASp is a key regulator of activity and stability in vivo MP Blundell, G Bouma, J Metelo, A Worth, Y Calle, LA Cowell, ... Proceedings of the National Academy of Sciences 106 (37), 15738-15743, 2009 | 72 | 2009 |
WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts D Malinova, M Fritzsche, CR Nowosad, H Armer, PMG Munro, ... Journal of Leucocyte Biology 99 (5), 699-710, 2016 | 68 | 2016 |
A partial down-regulation of WASP is sufficient to inhibit podosome formation in dendritic cells A Olivier, L Jeanson-Leh, G Bouma, D Compagno, J Blondeau, K Seye, ... Molecular Therapy 13 (4), 729-737, 2006 | 65 | 2006 |
Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells PP Lee, D Lobato-Márquez, N Pramanik, A Sirianni, V Daza-Cajigal, ... Nature communications 8 (1), 1576, 2017 | 61 | 2017 |
NOD mice have a severly impaired ability to recruit leukocytes into sites of inflammation G Bouma, T Nikolic, JMC Coppens, CG van Helden‐Meeuwsen, ... European journal of immunology 35 (1), 225-235, 2005 | 59 | 2005 |
Evidence for an enhanced adhesion of DC to fibronectin and a role of CCL19 and CCL21 in the accumulation of DC around the pre‐diabetic islets in NOD mice G Bouma, JMC Coppens, S Mourits, T Nikolic, S Sozzani, HA Drexhage, ... European journal of immunology 35 (8), 2386-2396, 2005 | 57 | 2005 |
Diabetes-prone NOD mice show an expanded subpopulation of mature circulating monocytes, which preferentially develop into macrophage-like cells in vitro T Nikolic, G Bouma, HA Drexhage, PJM Leenen Journal of leukocyte biology 78 (1), 70-79, 2005 | 53 | 2005 |
An increased MRP8/14 expression and adhesion, but a decreased migration towards proinflammatory chemokines of type 1 diabetes monocytes G Bouma, JMC Coppens, WK Lam-Tse, W Luini, K Sintnicolaas, ... Clinical & Experimental Immunology 141 (3), 509-517, 2005 | 48 | 2005 |