| Crystal structure of the β2 adrenergic receptor-Gs protein complex SGF Rasmussen, BT DeVree, Y Zou, AC Kruse, KY Chung, TS Kobilka, ... Nature 477 (7366), 549-555, 2011 | 3213 | 2011 |
| Structure of a nanobody-stabilized active state of the β2 adrenoceptor SGF Rasmussen, HJ Choi, JJ Fung, E Pardon, P Casarosa, PS Chae, ... Nature 469 (7329), 175-180, 2011 | 1880 | 2011 |
| Activation and allosteric modulation of a muscarinic acetylcholine receptor AC Kruse, AM Ring, A Manglik, J Hu, K Hu, K Eitel, H Hübner, E Pardon, ... Nature 504 (7478), 101-106, 2013 | 889 | 2013 |
| Structural insights into µ-opioid receptor activation W Huang, A Manglik, AJ Venkatakrishnan, T Laeremans, EN Feinberg, ... Nature 524 (7565), 315-321, 2015 | 810 | 2015 |
| Conformational biosensors reveal GPCR signalling from endosomes R Irannejad, JC Tomshine, JR Tomshine, M Chevalier, JP Mahoney, ... Nature 495 (7442), 534–538, 2013 | 753 | 2013 |
| A general protocol for the generation of Nanobodies for structural biology E Pardon, T Laeremans, S Triest, SGF Rasmussen, A Wohlkönig, A Ruf, ... Nature protocols 9 (3), 674-693, 2014 | 609 | 2014 |
| GABAA receptor signalling mechanisms revealed by structural pharmacology S Masiulis, R Desai, T Uchański, IS Martin, D Laverty, D Karia, ... Nature 565, 454-459, 2019 | 395 | 2019 |
| The F plasmid CcdB protein induces efficient ATP-dependent DNA cleavage by gyrase P Bernard, KE Kézdy, L Van Melderen, J Steyaert, L Wyns, ML Pato, ... Journal of molecular biology 234 (3), 534-541, 1993 | 335 | 1993 |
| Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor T Che, S Majumdar, SA Zaidi, P Ondachi, JD McCorvy, S Wang, ... Cell 172, 55–67, 2018 | 313 | 2018 |
| Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis TJ Cahill, ARB Thomsen, JT Tarrasch, B Plouffe, AH Nguyen, F Yang, ... Proceedings of the National Academy of Sciences 114, 2562-2567, 2017 | 305 | 2017 |
| Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation DP Staus, RT Strachan, A Manglik, B Pani, AW Kahsai, TH Kim, ... Nature 535 (7612), 448-452, 2016 | 300 | 2016 |
| Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer D Laverty, R Desai, T Uchański, S Masiulis, WJ Stec, T Malinauskas, ... Nature 565, 516-520, 2019 | 267 | 2019 |
| Structural flexibility of the Gαs α-helical domain in the β2-adrenoceptor Gs complex GH Westfield, SGF Rasmussen, M Su, S Dutta, BT DeVree, KY Chung, ... Proceedings of the National Academy of Sciences 108 (38), 16086-16091, 2011 | 267 | 2011 |
| Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain AB Ward, P Szewczyk, V Grimard, CW Lee, L Martinez, R Doshi, A Caya, ... Proceedings of the National Academy of Sciences 110 (33), 13386-13391, 2013 | 266 | 2013 |
| Influence of the π–π interaction on the hydrogen bonding capacity of stacked DNA/RNA bases P Mignon, S Loverix, J Steyaert, P Geerlings Nucleic Acids Research 33 (6), 1779-1789, 2005 | 266 | 2005 |
| Nanobody stabilization of G protein-coupled receptor conformational states J Steyaert, BK Kobilka Current opinion in structural biology 21 (4), 567-572, 2011 | 249 | 2011 |
| Propagation of conformational changes during µ-opioid receptor activation R Sounier, C Mas, J Steyaert, T Laeremans, A Manglik, W Huang, ... Nature 524 (7565), 375-378, 2015 | 239 | 2015 |
| Therapeutic nanoreactors: combining chemistry and biology in a novel triblock copolymer drug delivery system A Ranquin, W Versées, W Meier, J Steyaert, P Van Gelder Nano letters 5 (11), 2220-2224, 2005 | 239 | 2005 |
| Structural insights into the activation of metabotropic glutamate receptors A Koehl, H Hu, D Feng, B Sun, Y Zhang, MJ Robertson, M Chu, ... Nature 566, 79–84, 2019 | 231 | 2019 |
| Allosteric coupling from G protein to the agonist-binding pocket in GPCRs BT DeVree, JP Mahoney, GA Vélez-Ruiz, SGF Rasmussen, AJ Kuszak, ... Nature 535 (7610), 182-186, 2016 | 226 | 2016 |
Els Pardonvrije universiteit brusselVerified email at vub.ac.be
