Davide Trotti
Davide Trotti
Professor of Neuroscience, Thomas Jefferson University
Verified email at - Homepage
Cited by
Cited by
Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria
P Pasinelli, ME Belford, N Lennon, BJ Bacskai, BT Hyman, D Trotti, ...
Neuron 43 (1), 19-30, 2004
Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes
A Volterra, D Trotti, C Tromba, S Floridi, G Racagni
Journal of Neuroscience 14 (5), 2924-2932, 1994
Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration?
D Trotti, NC Danbolt, A Volterra
Trends in pharmacological sciences 19 (8), 328-334, 1998
Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death
X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ...
Neuron 84 (6), 1213-1225, 2014
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons
Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ...
Nature medicine 24 (3), 313-325, 2018
SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter
D Trotti, A Rolfs, NC Danbolt, RH Brown, MA Hediger
Nature neuroscience 2 (5), 427-433, 1999
Peroxynitrite Inhibits Glutamate Transporter Subtypes (∗)
D Trotti, D Rossi, O Gjesdal, LM Levy, G Racagni, NC Danbolt, A Volterra
Journal of Biological Chemistry 271 (11), 5976-5979, 1996
Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis
E Foran, D Trotti
Antioxidants & redox signaling 11 (7), 1587-1602, 2009
High sensitivity of glutamate uptake to extracellular free arachidonic acid levels in rat cortical synaptosomes and astrocytes
A Volterra, D Trotti, P Cassutti, C Tromba, A Salvaggio, RC Melcangi, ...
Journal of neurochemistry 59 (2), 600-606, 1992
Amyotrophic lateral sclerosis-linked glutamate transporter mutant has impaired glutamate clearance capacity
D Trotti, M Aoki, P Pasinelli, UV Berger, NC Danbolt, RH Brown, ...
Journal of Biological Chemistry 276 (1), 576-582, 2001
Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders
H Qosa, DS Miller, P Pasinelli, D Trotti
Brain research 1628, 298-316, 2015
Glutamate uptake is inhibited by arachidonic acid and oxygen radicals via two distinct and additive mechanisms.
A Volterra, D Trotti, G Racagni
Molecular pharmacology 46 (5), 986-992, 1994
Cell-to-cell transmission of dipeptide repeat proteins linked to C9orf72-ALS/FTD
T Westergard, BK Jensen, X Wen, J Cai, E Kropf, L Iacovitti, P Pasinelli, ...
Cell reports 17 (3), 645-652, 2016
Neuronal and glial glutamate transporters possess an SH‐based redox regulatory mechanism
D Trotti, BL Rizzini, D Rossi, O Haugeto, G Racagni, NC Danbolt, ...
European Journal of Neuroscience 9 (6), 1236-1243, 1997
An over-oxidized form of superoxide dismutase found in sporadic amyotrophic lateral sclerosis with bulbar onset shares a toxic mechanism with mutant SOD1
S Guareschi, E Cova, C Cereda, M Ceroni, E Donetti, DA Bosco, D Trotti, ...
Proceedings of the National Academy of Sciences 109 (13), 5074-5079, 2012
Caspase-3 cleaves and inactivates the glutamate transporter EAAT2
W Boston-Howes, SL Gibb, EO Williams, P Pasinelli, RH Brown, D Trotti
Journal of Biological Chemistry 281 (20), 14076-14084, 2006
ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2
S Pedrini, D Sau, S Guareschi, M Bogush, RH Brown Jr, N Naniche, A Kia, ...
Human molecular genetics 19 (15), 2974-2986, 2010
Regulation of glutamate transporters in health and disease
G Gegelashvili, MB Robinson, D Trotti, T Rauen
Progress in Brain Research 132, 267-286, 2001
Arachidonic Acid Inhibits a Purified and Reconstituted Glutamate Transporter Directly from the Water Phase and Not via the Phospholipid Membrane (∗)
D Trotti, A Volterra, KP Lehre, D Rossi, O Gjesdal, G Racagni, NC Danbolt
Journal of Biological Chemistry 270 (17), 9890-9895, 1995
Molecular characteristics of mammalian and insect amino acid transporters: implications for amino acid homeostasis
M Castagna, C Shayakul, D Trotti, VF Sacchi, WR Harvey, MA Hediger
Journal of Experimental Biology 200 (2), 269-286, 1997
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