Net charge per residue modulates conformational ensembles of intrinsically disordered proteins AH Mao, SL Crick, A Vitalis, CL Chicoine, RV Pappu Proceedings of the National Academy of Sciences 107 (18), 8183-8188, 2010 | 618 | 2010 |
Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide X Hu, SL Crick, G Bu, C Frieden, RV Pappu, JM Lee Proceedings of the National Academy of Sciences 106 (48), 20324-20329, 2009 | 500 | 2009 |
Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions SL Crick, M Jayaraman, C Frieden, R Wetzel, RV Pappu Proceedings of the National Academy of Sciences 103 (45), 16764-16769, 2006 | 339 | 2006 |
Unmasking the roles of N-and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation SL Crick, KM Ruff, K Garai, C Frieden, RV Pappu Proceedings of the National Academy of Sciences 110 (50), 20075-20080, 2013 | 242 | 2013 |
A polymer physics perspective on driving forces and mechanisms for protein aggregation RV Pappu, X Wang, A Vitalis, SL Crick Archives of biochemistry and biophysics 469 (1), 132-141, 2008 | 185 | 2008 |
Assessing micromechanical properties of cells with atomic force microscopy: importance of the contact point SL Crick, FCP Yin Biomechanics and modeling in mechanobiology 6 (3), 199-210, 2007 | 164 | 2007 |
Modulation of polyglutamine conformations and dimer formation by the N-terminus of huntingtin TE Williamson, A Vitalis, SL Crick, RV Pappu Journal of molecular biology 396 (5), 1295-1309, 2010 | 152 | 2010 |
Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers AE Posey, KM Ruff, TS Harmon, SL Crick, A Li, MI Diamond, RV Pappu Journal of Biological Chemistry 293 (10), 3734-3746, 2018 | 127 | 2018 |
The E. coli CsgB nucleator of curli assembles to ¥â-sheet oligomers that alter the CsgA fibrillization mechanism Q Shu, SL Crick, JS Pinkner, B Ford, SJ Hultgren, C Frieden Proceedings of the National Academy of Sciences 109 (17), 6502-6507, 2012 | 77 | 2012 |
N-terminal segments modulate the ¥á-helical propensities of the intrinsically disordered basic regions of bZIP proteins RK Das, SL Crick, RV Pappu Journal of molecular biology 416 (2), 287-299, 2012 | 70 | 2012 |
Expression and purification of amyloid-¥â peptides from Escherichia coli K Garai, SL Crick, SM Mustafi, C Frieden Protein expression and purification 66 (1), 107-112, 2009 | 50 | 2009 |
Substoichiometric inhibition of A¥â1–40 aggregation by a tandem A¥â40–1-Gly8-1-40 peptide SM Mustafi, K Garai, SL Crick, B Baban, C Frieden Biochemical and biophysical research communications 397 (3), 509-512, 2010 | 9 | 2010 |
Thermodynamic and Kinetic Models for Aggregation of Intrinsically Disordered Proteins SL Crick, RV Pappu Protein and Peptide Folding, Misfolding, and Non‐Folding, 413-440, 2012 | 7 | 2012 |
Plasmonic fluor-enhanced antigen arrays for high-throughput, serological studies of SARS-CoV-2 AJ Qavi, C Wu, M Lloyd, MMU Zaman, J Luan, C Ballman, DW Leung, ... ACS Infectious Diseases 8 (8), 1468-1479, 2022 | 5 | 2022 |
A Flexible, Quantitative Plasmonic-Fluor Lateral Flow Assay for the Rapid Detection of Orthoebolavirus zairense and Orthoebolavirus sudanense AJ Qavi, Q Jiang, MJ Aman, H Vu, L Zetlin, JM Dye, JW Froude, ... ACS Infectious Diseases 10 (1), 57-63, 2023 | 3 | 2023 |
Manipulating light for the detection of viruses in resource-limited settings AJ Qavi, Q Zhang, MJ Aman, H Vu, L Zetlin, JM Dye, JW Froude, ... Frontiers in Biological Detection: From Nanosensors to Systems XVI 12861, 45-48, 2024 | | 2024 |
Tracking the intracellular itinerary of APP and de novo A¥â generation using click chemistry I Xu, LR Czerniewski, Q Xiao, P Yan, A Benz, AG Cashikar, ... Alzheimer's & Dementia 19, e075424, 2023 | | 2023 |
Ultrabright fluorescent nanocomposite structures for enhanced fluorescent bioassays C Kercher, Q Jiang, SL Crick US Patent App. 17/759,829, 2023 | | 2023 |
P1‐194: TRACKING THE INTRACELLULAR ITINERARY OF APP AND DE NOVO AMYLOID BETA GENERATION USING CLICK CHEMISTRY LR Czerniewski, Q Xiao, K Bria, MI Kim, AG Cashikar, A Leng, A Benz, ... Alzheimer's & Dementia 14 (7S_Part_6), P353-P353, 2018 | | 2018 |
P1‐004: Amyloid seeds formed by cellular uptake, concentration, and aggergation of the Abeta1‐42 peptide JM Lee, S Crick, R Pappu, C Frieden, X Hu Alzheimer's & Dementia 5 (4S_Part_6), P173-P173, 2009 | | 2009 |