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Yftah Tal-Gan
Yftah Tal-Gan
Professor of Chemistry, University of Nevada, Reno
unr.edu의 이메일 확인됨 - 홈페이지
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Highly potent inhibitors of quorum sensing in Staphylococcus aureus revealed through a systematic synthetic study of the group-III autoinducing peptide
Y Tal-Gan, DM Stacy, MK Foegen, DW Koenig, HE Blackwell
Journal of the American Chemical Society 135 (21), 7869-7882, 2013
1462013
Highly Stable, Amide‐Bridged Autoinducing Peptide Analogues that Strongly Inhibit the AgrC Quorum Sensing Receptor in Staphylococcus aureus
Y Tal‐Gan, M Ivancic, G Cornilescu, T Yang, HE Blackwell
Angewandte Chemie 128 (31), 9059-9063, 2016
702016
Microwave-assisted solid-phase aza-peptide synthesis: aza scan of a PKB/Akt inhibitor using aza-arginine and aza-proline precursors
NS Freeman, Y Tal-Gan, S Klein, A Levitzki, C Gilon
The Journal of Organic Chemistry 76 (9), 3078-3085, 2011
692011
Structural characterization of native autoinducing peptides and abiotic analogues reveals key features essential for activation and inhibition of an AgrC quorum sensing …
Y Tal-Gan, M Ivancic, G Cornilescu, CC Cornilescu, HE Blackwell
Journal of the American Chemical Society 135 (49), 18436-18444, 2013
602013
Structure–Activity Relationships of the Competence Stimulating Peptides (CSPs) in Streptococcus pneumoniae Reveal Motifs Critical for Intra-group and Cross …
Y Yang, B Koirala, LA Sanchez, NR Phillips, SR Hamry, Y Tal-Gan
ACS chemical biology 12 (4), 1141-1151, 2017
552017
Simplified AIP‐II Peptidomimetics Are Potent Inhibitors of Staphylococcus aureus AgrC Quorum Sensing Receptors
JK Vasquez, Y Tal‐Gan, G Cornilescu, KA Tyler, HE Blackwell
ChemBioChem 18 (4), 413-423, 2017
552017
Structure–Function Analyses of a Staphylococcus epidermidis Autoinducing Peptide Reveals Motifs Critical for AgrC-type Receptor Modulation
T Yang, Y Tal-Gan, AE Paharik, AR Horswill, HE Blackwell
ACS chemical biology 11 (7), 1982-1991, 2016
532016
Nanoporous superhydrophobic coatings that promote the extended release of water-labile quorum sensing inhibitors and enable long-term modulation of quorum sensing in …
MJ Kratochvil, Y Tal-Gan, T Yang, HE Blackwell, DM Lynn
ACS biomaterials science & engineering 1 (10), 1039-1049, 2015
532015
Characterization of structural elements in native autoinducing peptides and non-native analogues that permit the differential modulation of AgrC-type quorum sensing receptors …
Y Tal-Gan, M Ivancic, G Cornilescu, HE Blackwell
Organic & biomolecular chemistry 14 (1), 113-121, 2016
482016
Surface Coatings that Promote Rapid Release of Peptide‐Based AgrC Inhibitors for Attenuation of Quorum Sensing in Staphylococcus aureus
AH Broderick, DM Stacy, Y Tal‐Gan, MJ Kratochvil, HE Blackwell, ...
Advanced healthcare materials 3 (1), 97-105, 2014
442014
N-Methyl and peptoid scans of an autoinducing peptide reveal new structural features required for inhibition and activation of AgrC quorum sensing receptors in Staphylococcus …
Y Tal-Gan, DM Stacy, HE Blackwell
Chemical communications 50 (23), 3000-3003, 2014
422014
Novel method for the synthesis of urea backbone cyclic peptides using new Alloc‐protected glycine building units
M Hurevich, Y Tal‐Gan, S Klein, Y Barda, A Levitzki, C Gilon
Journal of Peptide Science: An Official Publication of the European Peptide …, 2010
392010
Development and utilization of peptide-based quorum sensing modulators in Gram-positive bacteria
DN McBrayer, CD Cameron, Y Tal-Gan
Organic & biomolecular chemistry 18 (37), 7273-7290, 2020
352020
Designing cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity in Streptococcus pneumoniae
Y Yang, J Lin, A Harrington, G Cornilescu, GW Lau, Y Tal-Gan
Proceedings of the National Academy of Sciences 117 (3), 1689-1699, 2020
352020
Backbone cyclic peptide inhibitors of protein kinase B (PKB/Akt)
Y Tal-Gan, M Hurevich, S Klein, A Ben-Shimon, D Rosenthal, C Hazan, ...
Journal of medicinal chemistry 54 (14), 5154-5164, 2011
342011
Structure–Activity Relationships of the Competence Stimulating Peptide in Streptococcus mutans Reveal Motifs Critical for Membrane Protease SepM Recognition …
CR Bikash, SR Hamry, Y Tal-Gan
ACS infectious diseases 4 (9), 1385-1394, 2018
332018
Cyclic peptides that govern signal transduction pathways: From prokaryotes to multi-cellular organisms
RW Mull, A Harrington, LA Sanchez, Y Tal-Gan
Current topics in medicinal chemistry 18 (7), 625-644, 2018
322018
Development of a Dominant Negative Competence‐Stimulating Peptide (dnCSP) that Attenuates Streptococcus pneumoniae Infectivity in a Mouse Model of Acute …
B Koirala, J Lin, GW Lau, Y Tal‐Gan
ChemBioChem 19 (22), 2380-2386, 2018
272018
Metabolic Stability of Peptidomimetics: N‐Methyl and Aza Heptapeptide Analogs of a PKB/Akt Inhibitor
Y Tal‐Gan, NS Freeman, S Klein, A Levitzki, C Gilon
Chemical Biology & Drug Design 78 (5), 887-892, 2011
272011
Synthesis and structure–activity relationship studies of peptidomimetic PKB/Akt inhibitors: The significance of backbone interactions
Y Tal-Gan, NS Freeman, S Klein, A Levitzki, C Gilon
Bioorganic & medicinal chemistry 18 (8), 2976-2985, 2010
272010
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