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Martin Kampmann
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Genome-scale CRISPR-mediated control of gene repression and activation
LA Gilbert, MA Horlbeck, B Adamson, JE Villalta, Y Chen, EH Whitehead, ...
Cell 159 (3), 647-661, 2014
27012014
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
MA Horlbeck, LA Gilbert, JE Villalta, B Adamson, RA Pak, Y Chen, ...
elife 5, e19760, 2016
6912016
A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility
MC Bassik, M Kampmann, RJ Lebbink, S Wang, MY Hein, I Poser, ...
Cell 152 (4), 909-922, 2013
4152013
Mitochondrial stress is relayed to the cytosol by an OMA1–DELE1–HRI pathway
X Guo, G Aviles, Y Liu, R Tian, BA Unger, YHT Lin, AP Wiita, K Xu, ...
Nature 579 (7799), 427-432, 2020
3902020
Targeting the AAA ATPase p97 as an approach to treat cancer through disruption of protein homeostasis
DJ Anderson, R Le Moigne, S Djakovic, B Kumar, J Rice, S Wong, J Wang, ...
Cancer cell 28 (5), 653-665, 2015
3812015
LRP1 is a master regulator of tau uptake and spread
JN Rauch, G Luna, E Guzman, M Audouard, C Challis, YE Sibih, ...
Nature 580 (7803), 381-385, 2020
3722020
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing
JK Nuñez, J Chen, GC Pommier, JZ Cogan, JM Replogle, C Adriaens, ...
Cell 184 (9), 2503-2519. e17, 2021
3502021
CRISPR interference-based platform for multimodal genetic screens in human iPSC-derived neurons
R Tian, MA Gachechiladze, CH Ludwig, MT Laurie, JY Hong, D Nathaniel, ...
Neuron 104 (2), 239-255. e12, 2019
3152019
CRISPRi and CRISPRa screens in mammalian cells for precision biology and medicine
M Kampmann
ACS chemical biology 13 (2), 406-416, 2018
2912018
Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease
K Leng, E Li, R Eser, A Piergies, R Sit, M Tan, N Neff, SH Li, ...
Nature neuroscience 24 (2), 276-287, 2021
2682021
Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response
C Sidrauski, JC Tsai, M Kampmann, BR Hearn, P Vedantham, ...
elife 4, e07314, 2015
2542015
Mapping the genetic landscape of human cells
MA Horlbeck, A Xu, M Wang, NK Bennett, CY Park, D Bogdanoff, ...
Cell 174 (4), 953-967. e22, 2018
2522018
Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent
M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ...
Molecular cell 68 (1), 210-223. e6, 2017
2202017
The mTOR complex controls HIV latency
E Besnard, S Hakre, M Kampmann, HW Lim, NN Hosmane, A Martin, ...
Cell host & microbe 20 (6), 785-797, 2016
2082016
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity
YJ Zhang, L Guo, PK Gonzales, TF Gendron, Y Wu, K Jansen-West, ...
Science 363 (6428), eaav2606, 2019
2052019
Probing the global cellular responses to lipotoxicity caused by saturated fatty acids
M Piccolis, LM Bond, M Kampmann, P Pulimeno, C Chitraju, CBK Jayson, ...
Molecular cell 74 (1), 32-44. e8, 2019
2032019
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
R Tian, A Abarientos, J Hong, SH Hashemi, R Yan, N Dräger, K Leng, ...
Nature neuroscience 24 (7), 1020-1034, 2021
1802021
Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification
RM Deans, DW Morgens, A Ökesli, S Pillay, MA Horlbeck, M Kampmann, ...
Nature chemical biology 12 (5), 361-366, 2016
1732016
Tau internalization is regulated by 6-O sulfation on heparan sulfate proteoglycans (HSPGs)
JN Rauch, JJ Chen, AW Sorum, GM Miller, T Sharf, SK See, ...
Scientific reports 8 (1), 6382, 2018
1702018
Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells
M Kampmann, MC Bassik, JS Weissman
Proceedings of the National Academy of Sciences 110 (25), E2317-E2326, 2013
1462013
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