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Gabriel K. Griffin
Gabriel K. Griffin
Assistant Professor of Pathology, DFCI, BWH, HMS, Broad Institute
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Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
BC Miller, DR Sen, R Al Abosy, K Bi, YV Virkud, MW LaFleur, KB Yates, ...
Nature immunology 20 (3), 326-336, 2019
13542019
High-definition spatial transcriptomics for in situ tissue profiling
S Vickovic, G Eraslan, F Salmén, J Klughammer, L Stenbeck, D Schapiro, ...
Nature methods 16 (10), 987-990, 2019
8252019
Single-cell RNA-seq reveals AML hierarchies relevant to disease progression and immunity
P van Galen, V Hovestadt, MH Wadsworth II, TK Hughes, GK Griffin, ...
Cell 176 (6), 1265-1281. e24, 2019
7382019
NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis
JD Brown, CY Lin, Q Duan, G Griffin, AJ Federation, RM Paranal, S Bair, ...
Molecular cell 56 (2), 219-231, 2014
5952014
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
JJ Ishizuka, RT Manguso, CK Cheruiyot, K Bi, A Panda, A Iracheta-Vellve, ...
Nature 565 (7737), 43-48, 2019
5002019
IL-17 and TNF-α sustain neutrophil recruitment during inflammation through synergistic effects on endothelial activation
GK Griffin, G Newton, ML Tarrio, D Bu, E Maganto-Garcia, V Azcutia, ...
The Journal of Immunology 188 (12), 6287-6299, 2012
4022012
The human and mouse enteric nervous system at single-cell resolution
E Drokhlyansky, CS Smillie, N Van Wittenberghe, M Ericsson, GK Griffin, ...
Cell 182 (6), 1606-1622. e23, 2020
3382020
Genetic interleukin 6 signaling deficiency attenuates cardiovascular risk in clonal hematopoiesis
AG Bick, JP Pirruccello, GK Griffin, N Gupta, S Gabriel, D Saleheen, ...
Circulation 141 (2), 124-131, 2020
3042020
Mechanisms for the anti-inflammatory effects of statins
D Bu, G Griffin, AH Lichtman
Current opinion in lipidology 22 (3), 165-170, 2011
2802011
Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study
N Amabile, S Cheng, JM Renard, MG Larson, A Ghorbani, E McCabe, ...
European heart journal 35 (42), 2972-2979, 2014
2592014
Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity
GK Griffin, J Wu, A Iracheta-Vellve, JC Patti, J Hsu, T Davis, D Dele-Oni, ...
Nature 595 (7866), 309-314, 2021
2152021
Blastic plasmacytoid dendritic cell neoplasm is dependent on BCL2 and sensitive to venetoclax
J Montero, J Stephansky, T Cai, GK Griffin, L Cabal-Hierro, K Togami, ...
Cancer discovery 7 (2), 156-164, 2017
1992017
Relapsed or refractory double-expressor and double-hit lymphomas have inferior progression-free survival after autologous stem-cell transplantation
AF Herrera, M Mei, L Low, HT Kim, GK Griffin, JY Song, RW Merryman, ...
Journal of Clinical Oncology 35 (1), 24, 2017
1772017
Distinction of lymphoid and myeloid clonal hematopoiesis
A Niroula, A Sekar, MA Murakami, M Trinder, M Agrawal, WJ Wong, ...
Nature medicine 27 (11), 1921-1927, 2021
1512021
Association of clonal hematopoiesis with incident heart failure
B Yu, MB Roberts, LM Raffield, SM Zekavat, NQH Nguyen, ML Biggs, ...
Journal of the American College of Cardiology 78 (1), 42-52, 2021
1102021
The microenvironmental niche in classic Hodgkin lymphoma is enriched for CTLA-4–positive T cells that are PD-1–negative
SS Patel, JL Weirather, M Lipschitz, A Lako, PH Chen, GK Griffin, ...
Blood, The Journal of the American Society of Hematology 134 (23), 2059-2069, 2019
1092019
Clonal hematopoiesis is associated with higher risk of stroke
R Bhattacharya, SM Zekavat, J Haessler, M Fornage, L Raffield, ...
Stroke 53 (3), 788-797, 2022
1042022
Premature menopause, clonal hematopoiesis, and coronary artery disease in postmenopausal women
MC Honigberg, SM Zekavat, A Niroula, GK Griffin, AG Bick, JP Pirruccello, ...
Circulation 143 (5), 410-423, 2021
962021
Foxp3+-inducible regulatory T cells suppress endothelial activation and leukocyte recruitment
E Maganto-García, D Bu, ML Tarrio, P Alcaide, G Newton, GK Griffin, ...
The Journal of Immunology 187 (7), 3521-3529, 2011
952011
Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis
PG Kim, A Niroula, V Shkolnik, M McConkey, AE Lin, M Słabicki, JP Kemp, ...
Journal of Experimental Medicine 218 (12), e20211872, 2021
922021
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