Treatment of obesity with celastrol J Liu, J Lee, MAS Hernandez, R Mazitschek, U Ozcan Cell 161 (5), 999-1011, 2015 | 730 | 2015 |
Regulation of glucose homeostasis through a XBP-1–FoxO1 interaction Y Zhou, J Lee, CM Reno, C Sun, SW Park, J Chung, J Lee, SJ Fisher, ... Nature medicine 17 (3), 356-365, 2011 | 351 | 2011 |
Unfolded protein response signaling and metabolic diseases J Lee, U Ozcan Journal of Biological Chemistry 289 (3), 1203-1211, 2014 | 324 | 2014 |
p38 MAPK–mediated regulation of Xbp1s is crucial for glucose homeostasis J Lee, C Sun, Y Zhou, J Lee, D Gokalp, H Herrema, SW Park, RJ Davis, ... Nature medicine 17 (10), 1251-1260, 2011 | 260 | 2011 |
Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity SW Park, Y Zhou, J Lee, J Lee, U Ozcan Proceedings of the national academy of sciences 107 (45), 19320-19325, 2010 | 258 | 2010 |
Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice J Lee, J Liu, X Feng, MA Salazar Hernández, P Mucka, D Ibi, JW Choi, ... Nature medicine 22 (9), 1023-1032, 2016 | 227 | 2016 |
Selective chemical inhibition of PGC-1¥á gluconeogenic activity ameliorates type 2 diabetes K Sharabi, H Lin, CDJ Tavares, JE Dominy, JP Camporez, RJ Perry, ... Cell 169 (1), 148-160. e15, 2017 | 197 | 2017 |
IL1R1 is required for celastrol¡¯s leptin-sensitization and antiobesity effects X Feng, D Guan, T Auen, JW Choi, MA Salazar Hernández, J Lee, ... Nature medicine 25 (4), 575-582, 2019 | 116 | 2019 |
Inflammation improves glucose homeostasis through IKK¥â-XBP1s interaction J Liu, D Ibi, K Taniguchi, J Lee, H Herrema, B Akosman, P Mucka, ... Cell 167 (4), 1052-1066. e18, 2016 | 94 | 2016 |
The cholinesterase-like domain of thyroglobulin functions as an intramolecular chaperone J Lee, B Di Jeso, P Arvan The Journal of clinical investigation 118 (8), 2950-2958, 2008 | 67 | 2008 |
Oxidoreductase interactions include a role for ERp72 engagement with mutant thyroglobulin from the rdw/rdw rat dwarf S Menon, J Lee, WA Abplanalp, SE Yoo, T Agui, S Furudate, PS Kim, ... Journal of Biological Chemistry 282 (9), 6183-6191, 2007 | 55 | 2007 |
The cholinesterase-like domain, essential in thyroglobulin trafficking for thyroid hormone synthesis, is required for protein dimerization J Lee, X Wang, B Di Jeso, P Arvan Journal of Biological Chemistry 284 (19), 12752-12761, 2009 | 51 | 2009 |
Defective protein folding and intracellular retention of thyroglobulin-R19K mutant as a cause of human congenital goiter PS Kim, J Lee, P Jongsamak, S Menon, B Li, SA Hossain, JH Bae, ... Molecular endocrinology 22 (2), 477-484, 2008 | 42 | 2008 |
Identification of a new member of PBAN family and immunoreactivity in the central nervous system from Adoxophyes sp.(Lepidoptera: Tortricidae) MY Choi, JM Lee, KS Han, KS Boo Insect Biochemistry and Molecular Biology 34 (9), 927-935, 2004 | 40 | 2004 |
Cellular stress-modulating drugs can potentially be identified by in silico screening with connectivity map (CMap) Y Gao, S Kim, YI Lee, J Lee International journal of molecular sciences 20 (22), 5601, 2019 | 36 | 2019 |
PGC-1¥á functions as a co-suppressor of XBP1s to regulate glucose metabolism J Lee, MAS Hernández, T Auen, P Mucka, J Lee, U Ozcan Molecular metabolism 7, 119-131, 2018 | 32 | 2018 |
New insights into thyroglobulin pathophysiology revealed by the study of a family with congenital goiter D Peteiro-Gonzalez, J Lee, J Rodriguez-Fontan, I Castro-Piedras, ... The Journal of Clinical Endocrinology & Metabolism 95 (7), 3522-3526, 2010 | 30 | 2010 |
Cis and trans actions of the cholinesterase-like domain within the thyroglobulin dimer X Wang, J Lee, B Di Jeso, AS Treglia, D Comoletti, N Dubi, P Taylor, ... Journal of Biological Chemistry 285 (23), 17564-17573, 2010 | 29 | 2010 |
Maturation of thyroglobulin protein region I J Lee, B Di Jeso, P Arvan Journal of Biological Chemistry 286 (38), 33045-33052, 2011 | 27 | 2011 |
Amelioration of mitochondrial quality control and proteostasis by natural compounds in Parkinson¡¯s disease models B Cho, T Kim, YJ Huh, J Lee, YI Lee International journal of molecular sciences 20 (20), 5208, 2019 | 25 | 2019 |