Targeting transcription regulation in cancer with a covalent CDK7 inhibitor N Kwiatkowski, T Zhang, PB Rahl, BJ Abraham, J Reddy, SB Ficarro, ... Nature 511 (7511), 616-620, 2014 | 902 | 2014 |
Patient-derived models of acquired resistance can identify effective drug combinations for cancer AS Crystal, AT Shaw, LV Sequist, L Friboulet, MJ Niederst, EL Lockerman, ... Science 346 (6216), 1480-6, 2014 | 816 | 2014 |
Pharmacogenomic agreement between two cancer cell line data sets CCLE Consortium, GDSC Consortium Nature 528 (7580), 84-7, 2015 | 372* | 2015 |
Detection of dysregulated protein-association networks by high-throughput proteomics predicts cancer vulnerabilities JD Lapek Jr, P Greninger, R Morris, A Amzallag, I Pruteanu-Malinici, ... Nature biotechnology 35 (10), 983-989, 2017 | 157 | 2017 |
Probabilistic base calling of Solexa sequencing data J Rougemont, A Amzallag, C Iseli, L Farinelli, I Xenarios, F Naef BMC bioinformatics 9, 1-12, 2008 | 144 | 2008 |
Harnessing synthetic lethality to predict the response to cancer treatment JS Lee, A Das, L Jerby-Arnon, R Arafeh, N Auslander, M Davidson, ... Nature communications 9 (1), 2546, 2018 | 140 | 2018 |
Differential effector engagement by oncogenic KRAS TL Yuan, A Amzallag, R Bagni, M Yi, S Afghani, W Burgan, N Fer, ... Cell reports 22 (7), 1889-1902, 2018 | 133 | 2018 |
Bending modes of DNA directly addressed by cryo-electron microscopy of DNA minicircles D Demurtas, A Amzallag, EJ Rawdon, JH Maddocks, J Dubochet, ... Nucleic acids research 37 (9), 2882-2893, 2009 | 66 | 2009 |
Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation A Foudi, DJ Kramer, J Qin, D Ye, AS Behlich, S Mordecai, FI Preffer, ... Journal of Experimental Medicine 211 (5), 909-927, 2014 | 64 | 2014 |
3D reconstruction and comparison of shapes of DNA minicircles observed by cryo-electron microscopy A Amzallag, C Vaillant, M Jacob, M Unser, J Bednar, JD Kahn, ... Nucleic acids research 34 (18), e125-e125, 2006 | 59 | 2006 |
Landscape of targeted anti-cancer drug synergies in melanoma identifies a novel BRAF-VEGFR/PDGFR combination treatment AA Friedman, A Amzallag, I Pruteanu-Malinici, S Baniya, ZA Cooper, ... PloS one 10 (10), e0140310, 2015 | 45 | 2015 |
A landscape of response to drug combinations in non-small cell lung cancer NU Nair, P Greninger, X Zhang, AA Friedman, A Amzallag, E Cortez, ... Nature Communications 14 (1), 3830, 2023 | 40 | 2023 |
Preclinical anticancer efficacy of BET bromodomain inhibitors is determined by the apoptotic response AR Conery, RC Centore, KL Spillane, NE Follmer, A Bommi-Reddy, ... Cancer research 76 (6), 1313-1319, 2016 | 38 | 2016 |
Genome‐wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy AD Sahu, J S Lee, Z Wang, G Zhang, R Iglesias‐Bartolome, T Tian, Z Wei, ... Molecular systems biology 15 (3), e8323, 2019 | 34 | 2019 |
Statistical assessment and visualization of synergies for large-scale sparse drug combination datasets A Amzallag, S Ramaswamy, CH Benes BMC bioinformatics 20, 1-15, 2019 | 32 | 2019 |
The WTX tumor suppressor interacts with the transcriptional corepressor TRIM28 WJ Kim, BS Wittner, A Amzallag, BW Brannigan, DT Ting, S Ramaswamy, ... Journal of Biological Chemistry 290 (23), 14381-14390, 2015 | 27 | 2015 |
dREAM co-operates with insulator-binding proteins and regulates expression at divergently paired genes M Korenjak, E Kwon, RT Morris, E Anderssen, A Amzallag, ... Nucleic acids research 42 (14), 8939-8953, 2014 | 27 | 2014 |
Quasimesenchymal phenotype predicts systemic metastasis in pancreatic ductal adenocarcinoma KK Mahadevan, KS Arora, A Amzallag, E Williams, AS Kulkarni, ... Modern Pathology 32 (6), 844-854, 2019 | 6 | 2019 |
A landscape of synergistic drug combinations in non-small-cell lung cancer NU Nair, P Greninger, A Friedman, A Amzallag, E Cortez, AD Sahu, ... bioRxiv, 2021.06. 03.447011, 2021 | 3 | 2021 |
Consistency of drug profiles and predictors in large-scale cancer cell line data TCCL Encyclopedia, N Stransky, M Ghandi, GV Kryukov, LA Garraway, ... Nature 528 (7580), 84, 2015 | 3 | 2015 |