| Targeted Degradation of Oncogenic KRASG12C by VHL-recruiting PROTACs MJ Bond*, L Chu*, DA Nalawansha, K Li, CM Crews ACS Central Science 6 (8), 1367-1375, 2020 | 266 | 2020 |
| Synthesis of α‐Aryl Nitriles through Palladium‐Catalyzed Decarboxylative Coupling of Cyanoacetate Salts with Aryl Halides and Triflates R Shang, DS Ji, L Chu, Y Fu, L Liu Angewandte Chemie International Edition 19 (50), 4470-4474, 2011 | 248 | 2011 |
| Pd-catalyzed enantioselective C–H iodination: asymmetric synthesis of chiral diarylmethylamines L Chu, XC Wang, CE Moore, AL Rheingold, JQ Yu Journal of the American Chemical Society 135 (44), 16344-16347, 2013 | 231 | 2013 |
| Ligand-enabled cross-coupling of C(sp3)–H bonds with arylboron reagents via Pd(II)/Pd(0) catalysis KSL Chan, M Wasa, L Chu, BN Laforteza, M Miura, JQ Yu Nature chemistry 6 (2), 146-150, 2014 | 217 | 2014 |
| Room-temperature enantioselective C–H iodination via kinetic resolution L Chu, KJ Xiao, JQ Yu Science 346 (6208), 451-455, 2014 | 206 | 2014 |
| Remote Meta-C–H Activation Using a Pyridine-Based Template: Achieving Site-Selectivity via the Recognition of Distance and Geometry L Chu, M Shang, K Tanaka, Q Chen, N Pissarnitski, E Streckfuss, JQ Yu ACS Central Science 1 (7), 394-399, 2015 | 175 | 2015 |
| Palladium-catalyzed decarboxylative coupling of potassium nitrophenyl acetates with aryl halides R Shang, Z Huang, L Chu, Y Fu, L Liu Organic Letters 13 (16), 4240-4243, 2011 | 108 | 2011 |
| Enantioselective C− H Olefination of α‐Hydroxy and α‐Amino Phenylacetic Acids by Kinetic Resolution KJ Xiao, L Chu, JQ Yu Angewandte Chemie International Edition 55 (8), 2856-2860, 2016 | 103 | 2016 |
| Ligand‐Promoted ortho‐C–H Amination with Pd Catalysts D Zhu, G Yang, J He, L Chu, G Chen, W Gong, K Chen, MD Eastgate, ... Angewandte Chemie International Edition 54 (8), 2497-2500, 2015 | 97 | 2015 |
| Kinetic resolution of benzylamines via palladium (II)-catalyzed C–H cross-coupling KJ Xiao, L Chu, G Chen, JQ Yu Journal of the American Chemical Society 138 (24), 7796-7800, 2016 | 81 | 2016 |
| Pd-Catalyzed Remote Meta-C–H Functionalization of Phenylacetic Acids Using a Pyridine Template Z Jin*, L Chu*, YQ Chen, JQ Yu Organic letters 20 (2), 425-428, 2018 | 67 | 2018 |
| A role for Pd (IV) in catalytic enantioselective C–H functionalization with monoprotected amino acid ligands under mild conditions RE Plata, DE Hill, BE Haines, DG Musaev, L Chu, DP Hickey, MS Sigman, ... Journal of the American Chemical Society 139 (27), 9238-9245, 2017 | 60 | 2017 |
| Extremely bright, near-IR emitting spontaneously blinking fluorophores enable ratiometric multicolor nanoscopy in live cells J Tyson, K Hu, S Zheng, P Kidd, N Dadina, L Chu, D Toomre, ... ACS central science 7 (8), 1419-1426, 2021 | 39 | 2021 |
| Two-color nanoscopy of organelles for extended times with HIDE probes L Chu, J Tyson, JE Shaw, F Rivera-Molina, AJ Koleske, A Schepartz, ... Nature Communications, 2020 | 28 | 2020 |
| OligoTRAFTACs: a generalizable method for transcription factor degradation KTG Samarasinghe, E An, MA Genuth, L Chu, SA Holley, CM Crews RSC Chemical Biology 3 (9), 1144-1153, 2022 | 19 | 2022 |
| Targeted degradation of oncogenic KRASG12C by VHL-recruiting PROTACs. ACS Cent Sci. 2020; 6 (8): 1367–75 MJ Bond, L Chu, DA Nalawansha, K Li, CM Crews | 3 | |
| Self-Renewable Tag for Photostable Fluorescence Imaging of Proteins Z Du, W Wang, S Luo, L Zhang, S Yuan, Y Hei, Z Bao, C Chen, Y Lin, ... Journal of the American Chemical Society 145 (34), 18968-18976, 2023 | 2 | 2023 |
| Near-infrared light controlled protein degradation by photo-caged lenalidomide and pomalidomide Y Zhu, X Yan, Y Shi, B Liu, W Huang, L Chu Bioorganic Chemistry 143, 107050, 2024 | | 2024 |
| Compounds and methods for targeted degradation of kras L Chu, CM Crews, H Dong, KR Hornberger, JR Medina, L Snyder, J Wang US Patent App. 17/223,551, 2022 | | 2022 |
| Two-color long time-lapse super-resolution imaging with lipid probes L Chu, A Schepartz ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
jin-quan yuProfessor of Chemistry, The Scripps Research InstituteVerified email at scripps.edu
