Antibiotics for emerging pathogens MA Fischbach, CT Walsh Science 325 (5944), 1089-1093, 2009 | 2292 | 2009 |
Molecular mechanisms that confer antibacterial drug resistance C Walsh Nature 406 (6797), 775-781, 2000 | 2233 | 2000 |
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ... Natural product reports 30 (1), 108-160, 2013 | 2032 | 2013 |
Protein posttranslational modifications: the chemistry of proteome diversifications CT Walsh, S Garneau‐Tsodikova, GJ Gatto Jr Angewandte Chemie International Edition 44 (45), 7342-7372, 2005 | 1852 | 2005 |
Enzymatic reaction mechanisms C Walsh (No Title), 1979 | 1826 | 1979 |
Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: logic, machinery, and mechanisms MA Fischbach, CT Walsh Chemical reviews 106 (8), 3468-3496, 2006 | 1703 | 2006 |
Antibiotics: actions, origins, resistance. C Walsh | 1692 | 2003 |
Lessons from natural molecules J Clardy, C Walsh Nature 432 (7019), 829-837, 2004 | 1564 | 2004 |
The behavior and significance of slow-binding enzyme inhibitors JF Morrison, CT Walsh Adv Enzymol Relat Areas Mol Biol 61, 201-301, 1988 | 1408 | 1988 |
A new enzyme superfamily—the phosphopantetheinyl transferases RH Lambalot, AM Gehring, RS Flugel, P Zuber, M LaCelle, MA Marahiel, ... Chemistry & biology 3 (11), 923-936, 1996 | 1107 | 1996 |
Where will new antibiotics come from? C Walsh Nature Reviews Microbiology 1 (1), 65-70, 2003 | 1104 | 2003 |
Genetics and assembly line enzymology of siderophore biosynthesis in bacteria JH Crosa, CT Walsh Microbiology and molecular biology reviews 66 (2), 223-249, 2002 | 995 | 2002 |
Non-heme Fe (IV)–oxo intermediates C Krebs, D Galonic Fujimori, CT Walsh, JM Bollinger Jr Accounts of chemical research 40 (7), 484-492, 2007 | 958 | 2007 |
Functional association of cyclophilin A with HIV-1 virions M Thali, A Bukovsky, E Kondo, B Rosenwlrth, CT Walsh, J Sodroski, ... Nature 372 (6504), 363-365, 1994 | 885 | 1994 |
Harnessing the biosynthetic code: combinations, permutations, and mutations DE Cane, CT Walsh, C Khosla Science 282 (5386), 63-68, 1998 | 879 | 1998 |
Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 849 | 2015 |
Glycopeptide and lipoglycopeptide antibiotics D Kahne, C Leimkuhler, W Lu, C Walsh Chemical reviews 105 (2), 425-448, 2005 | 830 | 2005 |
Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA TDH Bugg, GD Wright, S Dutka-Malen, M Arthur, P Courvalin, CT Walsh Biochemistry 30 (43), 10408-10415, 1991 | 816 | 1991 |
Characterization of Sfp, a Bacillus subtilis Phosphopantetheinyl Transferase for Peptidyl Carrier Protein Domains in Peptide Synthetases LEN Quadri, PH Weinreb, M Lei, MM Nakano, P Zuber, CT Walsh Biochemistry 37 (6), 1585-1595, 1998 | 805 | 1998 |
New antibiotics from bacterial natural products J Clardy, MA Fischbach, CT Walsh Nature biotechnology 24 (12), 1541-1550, 2006 | 779 | 2006 |