Cheng Zhang
Cheng Zhang
Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine
Verified email at
Cited by
Cited by
Structure and function of an irreversible agonist-β2 adrenoceptor complex
DM Rosenbaum, C Zhang, JA Lyons, R Holl, D Aragao, DH Arlow, ...
Nature 469 (7329), 236-240, 2011
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
K Haga, AC Kruse, H Asada, T Yurugi-Kobayashi, M Shiroishi, C Zhang, ...
Nature 482 (7386), 547-551, 2012
High-resolution crystal structure of human protease-activated receptor 1
C Zhang, Y Srinivasan, DH Arlow, JJ Fung, D Palmer, Y Zheng, HF Green, ...
Nature 492 (7429), 387-392, 2012
Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2
Y Xiang, S Nambulli, Z Xiao, H Liu, Z Sang, WP Duprex, ...
Science 370 (6523), 1479-1484, 2020
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
M Zocher, C Zhang, SGF Rasmussen, BK Kobilka, DJ Müller
Proceedings of the National Academy of Sciences 109 (50), E3463-E3472, 2012
Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist
M Masureel, Y Zou, LP Picard, E van der Westhuizen, JP Mahoney, ...
Nature chemical biology 14 (11), 1059-1066, 2018
Cryo-EM structure of the human cannabinoid receptor CB2-Gi signaling complex
C Xing, Y Zhuang, TH Xu, Z Feng, XE Zhou, M Chen, L Wang, X Meng, ...
Cell 180 (4), 645-654. e13, 2020
The retromer component SNX6 interacts with dynactin p150Glued and mediates endosome-to-TGN transport
Z Hong, Y Yang, C Zhang, Y Niu, K Li, X Zhao, JJ Liu
Cell research 19 (12), 1334-1349, 2009
Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric Gi
X Qi, H Liu, B Thompson, J McDonald, C Zhang, X Li
Nature 571 (7764), 279-283, 2019
High-resolution laser-induced graphene. Flexible electronics beyond the visible limit
MG Stanford, C Zhang, JD Fowlkes, A Hoffman, IN Ivanov, PD Rack, ...
ACS applied materials & interfaces 12 (9), 10902-10907, 2020
Imaging G protein–coupled receptors while quantifying their ligand-binding free-energy landscape
D Alsteens, M Pfreundschuh, C Zhang, PM Spoerri, SR Coughlin, ...
Nature methods 12 (9), 845-851, 2015
Covalent agonists for studying G protein-coupled receptor activation
D Weichert, AC Kruse, A Manglik, C Hiller, C Zhang, H Hübner, ...
Proceedings of the National Academy of Sciences 111 (29), 10744-10748, 2014
High-performance multilayer WSe2 field-effect transistors with carrier type control
PR Pudasaini, A Oyedele, C Zhang, MG Stanford, N Cross, AT Wong, ...
Nano Research 11, 722-730, 2018
Structural insights into the human D1 and D2 dopamine receptor signaling complexes
Y Zhuang, P Xu, C Mao, L Wang, B Krumm, XE Zhou, S Huang, H Liu, ...
Cell 184 (4), 931-942. e18, 2021
Orthosteric and allosteric action of the C5a receptor antagonists
H Liu, HR Kim, RNVK Deepak, L Wang, KY Chung, H Fan, Z Wei, ...
Nature structural & molecular biology 25 (6), 472-481, 2018
Trypsin inhibitory loop is an excellent lead structure to design serine protease inhibitors and antimicrobial peptides
J Li, C Zhang, X Xu, J Wang, H Yu, R Lai, W Gong
The FASEB Journal 21 (10), 2466-2473, 2007
Structure of formylpeptide receptor 2-Gi complex reveals insights into ligand recognition and signaling
Y Zhuang, H Liu, X Edward Zhou, R Kumar Verma, PW de Waal, W Jang, ...
Nature communications 11 (1), 885, 2020
Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes
D Sun, Z Sang, YJ Kim, Y Xiang, T Cohen, AK Belford, A Huet, JF Conway, ...
Nature communications 12 (1), 4676, 2021
Identifying and quantifying two ligand-binding sites while imaging native human membrane receptors by AFM
M Pfreundschuh, D Alsteens, R Wieneke, C Zhang, SR Coughlin, ...
Nature communications 6 (1), 8857, 2015
G protein–coupled receptors in asthma therapy: pharmacology and drug action
SG Wendell, H Fan, C Zhang
Pharmacological reviews 72 (1), 1-49, 2020
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