Charles H. Li, PhD
Activation of proto-oncogenes by disruption of chromosome neighborhoods
D Hnisz, AS Weintraub, DS Day, AL Valton, RO Bak, CH Li, J Goldmann, ...
Science 351 (6280), 1454-1458, 2016
Coactivator condensation at super-enhancers links phase separation and gene control
BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ...
Science 361 (6400), eaar3958, 2018
YY1 is a structural regulator of enhancer-promoter loops
AS Weintraub, CH Li, AV Zamudio, AA Sigova, NM Hannett, DS Day, ...
Cell 171 (7), 1573-1588. e28, 2017
Mediator and RNA polymerase II clusters associate in transcription-dependent condensates
WK Cho, JH Spille, M Hecht, C Lee, C Li, V Grube, II Cisse
Science 361 (6400), 412-415, 2018
Transcription factors activate genes through the phase-separation capacity of their activation domains
A Boija, IA Klein, BR Sabari, A Dall’Agnese, EL Coffey, AV Zamudio, ...
Cell 175 (7), 1842-1855. e16, 2018
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene
XS Liu, H Wu, M Krzisch, X Wu, J Graef, J Muffat, D Hnisz, CH Li, B Yuan, ...
Cell 172 (5), 979-992. e6, 2018
Engineering of a histone-recognition domain in Dnmt3a alters the epigenetic landscape and phenotypic features of mouse ESCs
KM Noh, H Wang, HR Kim, W Wenderski, F Fang, CH Li, S Dewell, ...
Molecular cell 59 (1), 89-103, 2015
Small genomic insertions form enhancers that misregulate oncogenes
BJ Abraham, D Hnisz, AS Weintraub, N Kwiatkowski, CH Li, Z Li, ...
Nature communications 8, 14385, 2017
Chromatin kinases act on transcription factors and histone tails in regulation of inducible transcription
SZ Josefowicz, M Shimada, A Armache, CH Li, RM Miller, S Lin, A Yang, ...
Molecular cell 64 (2), 347-361, 2016
Mediator condensates localize signaling factors to key cell identity genes
AV Zamudio, A Dall’Agnese, JE Henninger, JC Manteiga, LK Afeyan, ...
Molecular Cell 76 (5), 753-766. e6, 2019
Regulation and dysregulation of chromosome structure in cancer
D Hnisz, J Schuijers, CH Li, RA Young
Annual Review of Cancer Biology 2, 21-40, 2018
Partitioning of cancer therapeutics in nuclear condensates
IA Klein, A Boija, LK Afeyan, SW Hawken, M Fan, A Dall'Agnese, O Oksuz, ...
Science 368 (6497), 1386-1392, 2020
MeCP2 links heterochromatin condensates and neurodevelopmental disease
CH Li, EL Coffey, A Dall’Agnese, NM Hannett, X Tang, JE Henninger, ...
Nature, 1-8, 2020
Methods of altering gene expression by perturbing transcription factor multimers that structure regulatory loops
RA Young, AS Weintraub, CH Li, AA Sigova
US Patent App. 16/476,868, 2019
Three-dimensional gene regulatory landscapes in normal and cancer cells
BJ Abraham, YE Guo, D Hnisz, CH Li, AS Weintraub, DS Day, J Schuijers, ...
Cancer Research 78 (13 Supplement), 971-971, 2018
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학술자료 1–15