John Laterra
John Laterra
Kennedy Krieger Institute & Johns Hopkins School of Medicine
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Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449
CM Rudin, CL Hann, J Laterra, RL Yauch, CA Callahan, L Fu, T Holcomb, ...
New England Journal of Medicine 361 (12), 1173-1178, 2009
Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts
L Zhuang, J Kim, RM Adam, KR Solomon, MR Freeman
The Journal of clinical investigation 115 (4), 959-968, 2005
Amide proton transfer (APT) contrast for imaging of brain tumors
J Zhou, B Lal, DA Wilson, J Laterra, PCM Van Zijl
Magnetic Resonance in Medicine: An Official Journal of the International …, 2003
Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides
J Zhou, E Tryggestad, Z Wen, B Lal, T Zhou, R Grossman, S Wang, K Yan, ...
Nature medicine 17 (1), 130-134, 2011
Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis
R Abounader, J Laterra
Neuro-oncology 7 (4), 436-451, 2005
Cell surface heparan sulfate mediates some adhesive responses to glycosaminoglycan-binding matrices, including fibronectin.
J Laterra, JE Silbert, LA Culp
The Journal of cell biology 96 (1), 112-123, 1983
Practical data acquisition method for human brain tumor amide proton transfer (APT) imaging
J Zhou, JO Blakeley, J Hua, M Kim, J Laterra, MG Pomper, PCM Van Zijl
Magnetic Resonance in Medicine: An Official Journal of the International …, 2008
Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme
MJ McGirt, KD Than, JD Weingart, KL Chaichana, FJ Attenello, A Olivi, ...
Journal of neurosurgery 110 (3), 583-588, 2009
c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
Y Li, A Li, M Glas, B Lal, M Ying, Y Sang, S Xia, D Trageser, ...
Proceedings of the National Academy of Sciences 108 (24), 9951-9956, 2011
In vivo targeting of SF/HGF and c‐met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis
R Abounader, B Lal, C Luddy, G Koe, B Davidson, EM Rosen, J Laterra
The FASEB Journal 16 (1), 1-16, 2002
Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature
AK Sills, JI Williams, BM Tyler, DS Epstein, EP Sipos, JD Davis, ...
Cancer Research 58 (13), 2784-2792, 1998
Cancer stem cells: distinct entities or dynamically regulated phenotypes?
Y Li, J Laterra
Cancer research 72 (3), 576-580, 2012
Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression
R Abounader, S Ranganathan, B Lal, K Fielding, A Book, H Dietz, ...
Journal of the National Cancer Institute 91 (18), 1548-1556, 1999
Scatter factor/hepatocyte growth factor protects against cytotoxic death in human glioblastoma via phosphatidylinositol 3-kinase-and AKT-dependent pathways
DC Bowers, S Fan, KA Walter, R Abounader, JA Williams, EM Rosen, ...
Cancer Research 60 (15), 4277-4283, 2000
Vascular gene expression in nonneoplastic and malignant brain
SL Madden, BP Cook, M Nacht, WD Weber, MR Callahan, Y Jiang, ...
The American journal of pathology 165 (2), 601-608, 2004
HGF/SF in angiogenesis
EM Rosen, K Lamszus, J Laterra, PJ Polverini, JS Rubin, ID Goldberg
Ciba Foundation Symposium 212‐Plasminogen‐Related Growth Factors …, 2007
Recurrence and malignant degeneration after resection of adult hemispheric low-grade gliomas
KL Chaichana, MJ McGirt, J Laterra, A Olivi, A Quiñones-Hinojosa
Journal of neurosurgery 112 (1), 10-17, 2010
Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts.
KJ Kim, L Wang, YC Su, GY Gillespie, A Salhotra, B Lal, J Laterra
Clinical Cancer Research 12 (4), 1292-1298, 2006
Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition
M Ying, S Wang, Y Sang, P Sun, B Lal, CR Goodwin, H Guerrero-Cazares, ...
Oncogene 30 (31), 3454-3467, 2011
The cytokine hepatocyte growth factor/scatter factor inhibits apoptosis and enhances DNA repair by a common mechanism involving signaling through phosphatidyl inositol 3′ kinase
S Fan, YX Ma, JA Wang, RQ Yuan, Q Meng, Y Cao, JJ Laterra, ...
Oncogene 19 (18), 2212-2223, 2000
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