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The drug binding site of human α1-acid glycoprotein: Insight from induced circular dichroism and electronic absorption spectra
F Zsila, Y Iwao
Biochimica et Biophysica Acta (BBA)-General Subjects 1770 (5), 797-809, 2007
Conformational stability and warfarin-binding properties of human serum albumin studied by recombinant mutants
Biochemical Journal 357 (1), 269-274, 2001
The structural and pharmacokinetic properties of oxidized human serum albumin, advanced oxidation protein products (AOPP)
Y Iwao, M Anraku, M Hiraike, K Kawai, K Nakajou, T Kai, A Suenaga, ...
Drug metabolism and pharmacokinetics 21 (2), 140-146, 2006
Chain length-dependent binding of fatty acid anions to human serum albumin studied by site-directed mutagenesis
U Kragh-Hansen, H Watanabe, K Nakajou, Y Iwao, M Otagiri
Journal of molecular biology 363 (3), 702-712, 2006
Transdermal protein delivery using choline and geranate (CAGE) deep eutectic solvent
A Banerjee, K Ibsen, Y Iwao, M Zakrewsky, S Mitragotri
Advanced healthcare materials 6 (15), 1601411, 2017
Freeze-dried nifedipine-lipid nanoparticles with long-term nano-dispersion stability after reconstitution
H Ohshima, A Miyagishima, T Kurita, Y Makino, Y Iwao, T Sonobe, S Itai
International journal of pharmaceutics 377 (1-2), 180-184, 2009
CD36 is one of important receptors promoting renal tubular injury by advanced oxidation protein products
Y Iwao, K Nakajou, R Nagai, K Kitamura, M Anraku, T Maruyama, ...
American Journal of Physiology-Renal Physiology 295 (6), F1871-F1880, 2008
Quantitative evaluation of the role of cysteine and methionine residues in the antioxidant activity of human serum albumin using recombinant mutants
Y Iwao, Y Ishima, J Yamada, T Noguchi, U Kragh‐Hansen, K Mera, ...
IUBMB life 64 (5), 450-454, 2012
Oxidation of Arg-410 promotes the elimination of human serum albumin
Y Iwao, M Anraku, K Yamasaki, U Kragh-Hansen, K Kawai, T Maruyama, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1764 (4), 743-749, 2006
Preparation and evaluation of swelling induced-orally disintegrating tablets by microwave irradiation
S Sano, Y Iwao, S Kimura, S Itai
International journal of pharmaceutics 416 (1), 252-259, 2011
Pharmacokinetics of single and repeated injection of hemoglobin-vesicles in hemorrhagic shock rat model
K Taguchi, T Maruyama, Y Iwao, H Sakai, K Kobayashi, H Horinouchi, ...
Journal of controlled release 136 (3), 232-239, 2009
A uremic toxin, 3-carboxy-4-methyl-5-propyl-2-furanpropionate induces cell damage to proximal tubular cells via the generation of a radical intermediate
Y Miyamoto, Y Iwao, K Mera, H Watanabe, D Kadowaki, Y Ishima, ...
Biochemical pharmacology 84 (9), 1207-1214, 2012
The ligand activity of AGE-proteins to scavenger receptors is dependent on their rate of modification by AGEs
R Nagai, K Mera, K Nakajou, Y Fujiwara, Y Iwao, H Imai, T Murata, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1772 (11-12 …, 2007
A comparative study of glycerin fatty acid ester and magnesium stearate on the dissolution of acetaminophen tablets using the analysis of available surface area
T Uchimoto, Y Iwao, K Takahashi, S Tanaka, Y Agata, T Iwamura, ...
European journal of pharmaceutics and biopharmaceutics 78 (3), 492-498, 2011
Clarithromycin highly-loaded gastro-floating fine granules prepared by high-shear melt granulation can enhance the efficacy of Helicobacter pylori eradication
H Aoki, Y Iwao, M Mizoguchi, S Noguchi, S Itai
European journal of pharmaceutics and biopharmaceutics 92, 22-27, 2015
Application of principal component analysis enables to effectively find important physical variables for optimization of fluid bed granulator conditions
T Otsuka, Y Iwao, A Miyagishima, S Itai
International journal of pharmaceutics 409 (1-2), 81-88, 2011
Hydrolysis of angiotensin II receptor blocker prodrug olmesartan medoxomil by human serum albumin and identification of its catalytic active sites
SF Ma, M Anraku, Y Iwao, K Yamasaki, U Kragh-Hansen, N Yamaotsu, ...
Drug Metabolism and Disposition 33 (12), 1911-1919, 2005
Investigation of internal structure of fine granules by microtomography using synchrotron X-ray radiation
S Noguchi, R Kajihara, Y Iwao, Y Fujinami, Y Suzuki, Y Terada, K Uesugi, ...
International journal of pharmaceutics 445 (1-2), 93-98, 2013
The uremic solute indoxyl sulfate acts as an antioxidant against superoxide anion radicals under normal‐physiological conditions
Y Miyamoto, Y Iwao, Y Tasaki, K Sato, Y Ishima, H Watanabe, ...
FEBS letters 584 (13), 2816-2820, 2010
Changes of net charge and α-helical content affect the pharmacokinetic properties of human serum albumin
Y Iwao, M Hiraike, U Kragh-Hansen, K Mera, T Noguchi, M Anraku, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1774 (12), 1582-1590, 2007
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