Precise maps of RNA polymerase reveal how promoters direct initiation and pausing H Kwak, NJ Fuda, LJ Core, JT Lis Science 339 (6122), 950-953, 2013 | 797 | 2013 |
Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons I Jonkers, H Kwak, JT Lis elife 3, e02407, 2014 | 601 | 2014 |
m6A enhances the phase separation potential of mRNA RJ Ries, S Zaccara, P Klein, A Olarerin-George, S Namkoong, ... Nature 571 (7765), 424-428, 2019 | 531 | 2019 |
Control of transcriptional elongation H Kwak, JT Lis Annual review of genetics 47, 483-508, 2013 | 474 | 2013 |
Base-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq) DB Mahat, H Kwak, GT Booth, IH Jonkers, CG Danko, RK Patel, ... Nature protocols 11 (8), 1455-1476, 2016 | 440 | 2016 |
Defining the status of RNA polymerase at promoters LJ Core, JJ Waterfall, DA Gilchrist, DC Fargo, H Kwak, K Adelman, JT Lis Cell reports 2 (4), 1025-1035, 2012 | 271 | 2012 |
Systematic characterization of stress-induced RNA granulation S Namkoong, A Ho, YM Woo, H Kwak, JH Lee Molecular cell 70 (1), 175-187. e8, 2018 | 219 | 2018 |
Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size MB Johnson, X Sun, A Kodani, R Borges-Monroy, KM Girskis, SC Ryu, ... Nature 556 (7701), 370-375, 2018 | 149 | 2018 |
Genome-wide control of RNA polymerase II activity by cohesin CA Schaaf, H Kwak, A Koenig, Z Misulovin, DW Gohara, A Watson, ... PLoS genetics 9 (3), e1003382, 2013 | 119 | 2013 |
Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme T Chu, EJ Rice, GT Booth, HH Salamanca, Z Wang, LJ Core, SL Longo, ... Nature genetics 50 (11), 1553-1564, 2018 | 115 | 2018 |
The Hmr and Lhr Hybrid Incompatibility Genes Suppress a Broad Range of Heterochromatic Repeats PRV Satyaki, TN Cuykendall, KHC Wei, NJ Brideau, H Kwak, S Aruna, ... PLoS genetics 10 (3), e1004240, 2014 | 98 | 2014 |
Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-α mRNA MJ Chae, HY Sung, EH Kim, M Lee, H Kwak, CH Chae, S Kim, WY Park Experimental & molecular medicine 41 (11), 824-831, 2009 | 95 | 2009 |
High-resolution mapping of RNA polymerases identifies mechanisms of sensitivity and resistance to BET inhibitors in t (8; 21) AML Y Zhao, Q Liu, P Acharya, KR Stengel, Q Sheng, X Zhou, H Kwak, ... Cell reports 16 (7), 2003-2016, 2016 | 75 | 2016 |
Defining NELF-E RNA binding in HIV-1 and promoter-proximal pause regions JM Pagano, H Kwak, CT Waters, RO Sprouse, BS White, A Ozer, K Szeto, ... PLoS genetics 10 (1), e1004090, 2014 | 65 | 2014 |
Kinetics of promoter Pol II on Hsp70 reveal stable pausing and key insights into its regulation MS Buckley, H Kwak, WR Zipfel, JT Lis Genes & development 28 (1), 14-19, 2014 | 62 | 2014 |
TED-Seq identifies the dynamics of poly (A) length during ER stress YM Woo, Y Kwak, S Namkoong, K Kristjánsdóttir, SH Lee, JH Lee, ... Cell reports 24 (13), 3630-3641. e7, 2018 | 56 | 2018 |
RNA-DNA differences are generated in human cells within seconds after RNA exits polymerase II IX Wang, LJ Core, H Kwak, L Brady, A Bruzel, L McDaniel, AL Richards, ... Cell reports 6 (5), 906-915, 2014 | 53 | 2014 |
Single-cell transcriptome analysis of colon cancer cell response to 5-fluorouracil-induced DNA damage SR Park, S Namkoong, L Friesen, CS Cho, ZZ Zhang, YC Chen, E Yoon, ... Cell reports 32 (8), 2020 | 49 | 2020 |
Population-scale study of eRNA transcription reveals bipartite functional enhancer architecture K Kristjánsdóttir, A Dziubek, HM Kang, H Kwak Nature communications 11 (1), 5963, 2020 | 36 | 2020 |
Chromatin architecture of the Pitx2 locus requires CTCF-and Pitx2-dependent asymmetry that mirrors embryonic gut laterality IC Welsh, H Kwak, FL Chen, M Werner, LS Shopland, CG Danko, JT Lis, ... Cell reports 13 (2), 337-349, 2015 | 36 | 2015 |