Reversing a model of Parkinson¡¯s disease with in situ converted nigral neurons H Qian, X Kang, J Hu, D Zhang, Z Liang, F Meng, X Zhang, Y Xue, ... Nature 582 (7813), 550-556, 2020 | 433 | 2020 |
R-ChIP using inactive RNase H reveals dynamic coupling of R-loops with transcriptional pausing at gene promoters L Chen, JY Chen, X Zhang, Y Gu, R Xiao, C Shao, P Tang, H Qian, D Luo, ... Molecular cell 68 (4), 745-757. e5, 2017 | 365 | 2017 |
The augmented R-loop is a unifying mechanism for myelodysplastic syndromes induced by high-risk splicing factor mutations L Chen, JY Chen, YJ Huang, Y Gu, J Qiu, H Qian, C Shao, X Zhang, J Hu, ... Molecular cell 69 (3), 412-425. e6, 2018 | 283 | 2018 |
Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction ZN Zhang, BC Freitas, H Qian, J Lux, A Acab, CA Trujillo, RH Herai, ... Proceedings of the National Academy of Sciences 113 (12), 3185-3190, 2016 | 171 | 2016 |
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells Y Xue*, H Qian*, J Hu, B Zhou, Y Zhou, X Hu, A Karakhanyan, Z Pang, ... Nature neuroscience 19 (6), 807, 2016 | 109 | 2016 |
PTB/nPTB: master regulators of neuronal fate in mammals J Hu, H Qian, Y Xue, XD Fu Biophysics reports 4, 204-214, 2018 | 66 | 2018 |
Physiological synaptic signals initiate sequential spikes at soma of cortical pyramidal neurons R Ge, H Qian, JH Wang Molecular brain 4, 1-8, 2011 | 50 | 2011 |
Axons amplify somatic incomplete spikes into uniform amplitudes in mouse cortical pyramidal neurons N Chen, J Yu, H Qian, R Ge, JH Wang PLoS One 5 (7), e11868, 2010 | 44 | 2010 |
Quantal glutamate release is essential for reliable neuronal encodings in cerebral networks J Yu*, H Qian*, N Chen, JH Wang PLoS One 6 (9), e25219, 2011 | 41 | 2011 |
Upregulation of transmitter release probability improves a conversion of synaptic analogue signals into neuronal digital spikes J Yu, H Qian, JH Wang Molecular Brain 5, 1-13, 2012 | 38 | 2012 |
Input-dependent subcellular localization of spike initiation between soma and axon at cortical pyramidal neurons R Ge, H Qian, N Chen, JH Wang Molecular brain 7, 1-16, 2014 | 34 | 2014 |
Rapamycin suppresses the recurrent excitatory circuits of dentate gyrus in a mouse model of temporal lobe epilepsy H Tang, H Long, C Zeng, Y Li, F Bi, J Wang, H Qian, B Xiao Biochemical and biophysical research communications 420 (1), 199-204, 2012 | 33 | 2012 |
A portion of inhibitory neurons in human temporal lobe epilepsy are functionally upregulated: an endogenous mechanism for seizure termination B Wen*, H Qian*, J Feng, RJ Ge, X Xu, ZQ Cui, RY Zhu, LS Pan, ZP Lin, ... CNS neuroscience & therapeutics 21 (2), 204-214, 2015 | 29 | 2015 |
Functional compatibility between Purkinje cell axon branches and their target neurons in the cerebellum Z Yang, N Chen, R Ge, H Qian, JH Wang Oncotarget 8 (42), 72424, 2017 | 24* | 2017 |
Bavc: Classifying benign atomicity violations via machine learning QC Chen, ZF Chen, Z Liu, X Feng, ZG Jiang, LQ Wang, HY Ma, P Guo, ... Advanced Materials Research 765, 1576-1580, 2013 | 14 | 2013 |
Single-cell transcriptome reveals diversity of Müller cells with different metabolic-mitochondrial signatures in normal and degenerated macula B Liu, J He, L Zhong, L Huang, B Gong, J Hu, H Qian, Z Yang Frontiers in Neuroscience 16, 1079498, 2022 | 11 | 2022 |
Reply to: Ptbp1 deletion does not induce astrocyte-to-neuron conversion Y Hao, J Hu, Y Xue, SF Dowdy, WC Mobley, H Qian, XD Fu Nature 618 (7964), E8-E13, 2023 | 10 | 2023 |
Brain repair by cell replacement via in situ neuronal reprogramming H Qian, XD Fu Annual review of genetics 55 (1), 45-69, 2021 | 10 | 2021 |
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis X Yang, C Gu, J Cai, F Li, X He, L Luo, W Xiao, B Hu, J Hu, H Qian, S Ren, ... Redox Biology 69, 103002, 2024 | 3 | 2024 |
Cockayne syndrome linked to elevated R-loops induced by stalled RNA polymerase II during transcription elongation X Zhang, J Xu, J Hu, S Zhang, Y Hao, D Zhang, H Qian, D Wang, XD Fu Nature Communications 15 (1), 6031, 2024 | 2 | 2024 |