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Lu Zhang
Lu Zhang
Senior Scientist, Oncology Discovery, Abbvie Inc.
Verified email at abbvie.com
Title
Cited by
Cited by
Year
Multiple roles of APC and its therapeutic implications in colorectal cancer
L Zhang, JW Shay
Journal Of The National Cancer Institute 109 (8), djw332, 2017
3622017
Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer
EJ Faivre, KF McDaniel, DH Albert, SR Mantena, JP Plotnik, D Wilcox, ...
Nature, 1-5, 2020
2932020
Acquired resistance to BET-PROTACs (proteolysis-targeting chimeras) caused by genomic alterations in core components of E3 ligase complexes
L Zhang, B Riley-Gillis, P Vijay, Y Shen
Molecular cancer therapeutics 18 (7), 1302-1311, 2019
2102019
NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer
AT Ludlow, MS Wong, JD Robin, K Batten, L Yuan, TP Lai, N Dahlson, ...
Nature Communications 9 (1), 3112, 2018
762018
Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer
JKDBJWS Lu Zhang, Panayotis C. Theodoropoulos, Ugur Eskiocak, Wentian Wang ...
Science Translational Medicine 8 (361), 2016
702016
Radiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses
SB Kim, RG Bozeman, A Kaisani, W Kim, L Zhang, JA Richardson, ...
Oncogene, 2015
422015
Cholesterol Depletion by TASIN-1 Induces Apoptotic Cell Death through the ER Stress/ROS/JNK Signaling in Colon Cancer Cells
L Zhang, SB Kim, K Luitel, JW Shay
Molecular Cancer Therapeutics, molcanther. 0887.2017, 2018
302018
Exome sequencing of normal and isogenic transformed human colonic epithelial cells (HCECs) reveals novel genes potentially involved in the early stages of colorectal tumorigenesis
L Zhang, SB Kim, G Jia, A Buhmeida, A Dallol, WE Wright, AJ Fornace, ...
BMC genomics 16 (1), S8, 2015
292015
Identification of novel driver tumor suppressors through functional interrogation of putative passenger mutations in colorectal cancer
L Zhang, K Komurov, WE Wright, JW Shay
International Journal of Cancer 132 (3), 732-737, 2013
262013
Inhibition of microRNA-31-5p protects human colonic epithelial cells against ionizing radiation
SB Kim, L Zhang, S Barron, JW Shay
Life Sciences in Space Research 1, 67-73, 2014
232014
Mitigation of radiation-induced damage by targeting egfr in noncancerous human epithelial cells
SB Kim, P Ly, A Kaisani, L Zhang, WE Wright, JW Shay
Radiation research 180 (3), 259-267, 2013
182013
Design and Synthesis of TASIN Analogues Specifically Targeting Colorectal Cancer Cell Lines with Mutant Adenomatous Polyposis Coli (APC)
W Wang, L Zhang, L Morlock, NS Williams, JW Shay, JK De Brabander
Journal of medicinal chemistry, 2019
172019
Truncated APC Mutation Induces Asef Activated Golgi Fragmentation
SB Kim, L Zhang, J Yoon, J Lee, J Min, W Li, NV Grishin, YA Moon, ...
Molecular and cellular biology, MCB. 00135-18, 2018
142018
Oxygen and Silicon Ion Particles Induce Neoplastic Transformation in Human Colonic Epithelial Cells
SB Kim, L Zhang, JW Shay
Gravitational and Space Research 2 (1), 2014
12014
Therapeutic targeting truncated adenomatous polyposis coli (APC) proteins for the selective killing of colorectal cancer cells
L Zhang, SB Kim, U Eskiocak, B Posner, P Das, WE Wright, ...
BMC Genomics 15 (S2), O3, 2014
12014
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