| Inhibition by cAMP of Ras-dependent activation of Raf SJ Cook, F McCormick Science 262 (5136), 1069-1072, 1993 | 1192 | 1993 |
| Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival HL Roderick, SJ Cook Nature Reviews Cancer 8 (5), 361-375, 2008 | 829 | 2008 |
| Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim R Ley, K Balmanno, K Hadfield, C Weston, SJ Cook Journal of Biological Chemistry 278 (21), 18811-18816, 2003 | 782 | 2003 |
| Characterization of two alternately spliced forms of phospholipase D1: activation of the purified enzymes by phosphatidylinositol 4, 5-bisphosphate, ADP-ribosylation factor … SM Hammond, JM Jenco, S Nakashima, K Cadwallader, Q Gu, S Cook, ... Journal of Biological Chemistry 272 (6), 3860-3868, 1997 | 607 | 1997 |
| MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road CJ Caunt, MJ Sale, PD Smith, SJ Cook Nature Reviews Cancer 15, 577–592, 2015 | 575 | 2015 |
| Tumour cell survival signalling by the ERK1/2 pathway K Balmanno, SJ Cook Cell Death & Differentiation 16 (3), 368-377, 2009 | 574 | 2009 |
| Rap1V12 antagonises Ras-dependent activation of ERK1 & ERK2 by LPA and EGF in Rat-1 fibroblasts S Cook, B Rubinfeld, F Albert, I & McCormick EMBO Journal 12, 3475-3485, 1993 | 452 | 1993 |
| FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency G Ficz, TA Hore, F Santos, HJ Lee, W Dean, J Arand, F Krueger, D Oxley, ... Cell stem cell 13 (3), 351-359, 2013 | 443 | 2013 |
| The role of MAPK signalling pathways in the response to endoplasmic reticulum stress NJ Darling, SJ Cook Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (10), 2150-2163, 2014 | 413 | 2014 |
| Regulatory phosphorylation of Bim: sorting out the ERK from the JNK R Ley, KE Ewings, K Hadfield, SJ Cook Cell death and differentiation 12 (8), 1008-1014, 2005 | 397 | 2005 |
| Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells K Balmanno, SJ Cook Oncogene 18 (20), 3085-3097, 1999 | 305 | 1999 |
| Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt A Sunters, PA Madureira, KM Pomeranz, M Aubert, JJ Brosens, SJ Cook, ... Cancer research 66 (1), 212-220, 2006 | 304 | 2006 |
| The Repertoire of Fos and Jun Proteins Expressed during the G1 Phase of the Cell Cycle Is Determined by the Duration of Mitogen-Activated Protein Kinase … SJ Cook, N Aziz, M McMahon Molecular and Cellular Biology 19 (1), 330-341, 1999 | 253 | 1999 |
| Extracellular signal-regulated kinases 1/2 are serum-stimulated “BimEL kinases” that bind to the BH3-only protein BimEL causing its phosphorylation and turnover R Ley, KE Ewings, K Hadfield, E Howes, K Balmanno, SJ Cook Journal of Biological Chemistry 279 (10), 8837-8847, 2004 | 249 | 2004 |
| Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells AS Little, K Balmanno, MJ Sale, S Newman, JR Dry, M Hampson, ... Science signaling 4 (166), ra17-ra17, 2011 | 247 | 2011 |
| De-regulated FGF receptors as therapeutic targets in cancer V Knights, SJ Cook Pharmacology & therapeutics 125 (1), 105-117, 2010 | 235 | 2010 |
| Analysis of the water-soluble products of phosphatidylcholine breakdown by ion-exchange chromatography. Bombesin and TPA (12-O-tetradecanoylphorbol 13 … SJ Cook, MJO Wakelam Biochemical Journal 263 (2), 581-587, 1989 | 234 | 1989 |
| Nucleotide-binding oligomerization domain-1 and epidermal growth factor receptor: critical regulators of β-defensins during Helicobacter pylori infection PK Boughan, RH Argent, M Body-Malapel, JH Park, KE Ewings, ... Journal of Biological Chemistry 281 (17), 11637-11648, 2006 | 231 | 2006 |
| The selective protein kinase C inhibitor, Ro-31-8220, inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) expression, induces c-Jun expression, and activates Jun N … J Beltman, F McCormick, SJ Cook Journal of Biological Chemistry 271 (43), 27018-27024, 1996 | 230 | 1996 |
| Activation of ERK1/2 by ΔRaf-1: ER* represses Bim expression independently of the JNK or PI3K pathways CR Weston, K Balmanno, C Chalmers, K Hadfield, SA Molton, R Ley, ... Oncogene 22 (9), 1281-1293, 2003 | 229 | 2003 |
kathryn balmannoBabraham InstituteVerified email at babraham.ac.uk
