Structural basis for the auxin-induced transcriptional regulation by Aux/IAA17 M Han, Y Park, I Kim, EH Kim, TK Yu, S Rhee, JY Suh Proceedings of the National Academy of Sciences 111 (52), 18613-18618, 2014 | 84 | 2014 |
Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA) S Abdeen, T Kunkle, N Salim, AM Ray, N Mammadova, C Summers, ... Journal of medicinal chemistry 61 (16), 7345-7357, 2018 | 40 | 2018 |
Structure of bacteriophage SPN 1 S endolysin reveals an unusual two‐module fold for the peptidoglycan lytic and binding activity Y Park, JA Lim, M Kong, S Ryu, S Rhee Molecular microbiology 92 (2), 316-325, 2014 | 37 | 2014 |
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules M Stevens, S Abdeen, N Salim, AM Ray, A Washburn, S Chitre, J Sivinski, ... Bioorganic & medicinal chemistry letters 29 (9), 1106-1112, 2019 | 33 | 2019 |
The Parkinson's disease–associated mutation N1437H impairs conformational dynamics in the G domain of LRRK2 X Huang, C Wu, Y Park, X Long, QQ Hoang, J Liao The FASEB Journal 33 (4), 4814, 2019 | 28 | 2019 |
Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics CX Wu, J Liao, Y Park, X Reed, VA Engel, NC Hoang, Y Takagi, ... Journal of Biological Chemistry 294 (15), 5907-5913, 2019 | 26 | 2019 |
Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus T Kunkle, S Abdeen, N Salim, AM Ray, M Stevens, AJ Ambrose, ... Journal of medicinal chemistry 61 (23), 10651-10664, 2018 | 26 | 2018 |
Crystal structure and functional analysis of isocitrate lyases from Magnaporthe oryzae and Fusarium graminearum Y Park, Y Cho, YH Lee, YW Lee, S Rhee Journal of Structural Biology 194 (3), 395-403, 2016 | 18 | 2016 |
Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections A Washburn, S Abdeen, Y Ovechkina, AM Ray, M Stevens, S Chitre, ... Bioorganic & medicinal chemistry letters 29 (13), 1665-1672, 2019 | 16 | 2019 |
Crystal structure of the effector protein HopA1 from Pseudomonas syringae Y Park, I Shin, S Rhee Journal of structural biology 189 (3), 276-280, 2015 | 12 | 2015 |
Analogs of nitrofuran antibiotics are potent GroEL/ES inhibitor pro-drugs M Stevens, C Howe, AM Ray, A Washburn, S Chitre, J Sivinski, Y Park, ... Bioorganic & medicinal chemistry 28 (22), 115710, 2020 | 11 | 2020 |
Functional differences between E. Coli and eskape pathogen groes/groel J Sivinski, AJ Ambrose, I Panfilenko, CJ Zerio, JM Machulis, N Mollasalehi, ... Mbio 12 (1), 10.1128/mbio. 02167-20, 2021 | 8 | 2021 |
Roc, the G-domain of the Parkinson’s disease-associated protein LRRK2 Y Park, J Liao, QQ Hoang Trends in biochemical sciences 47 (12), 1038-1047, 2022 | 5 | 2022 |
Functional differences between E. coli and ESKAPE pathogen GroES J Sivinski, AJ Ambrose, I Panfilenko, CJ Zerio, JM Machulis, N Mollasalehi, ... GroEL. mBio 12 (1), 2021 | 5 | 2021 |
A revised 1.6 Å structure of the GTPase domain of the Parkinson’s disease-associated protein LRRK2 provides insights into mechanisms CX Wu, J Liao, Y Park, NC Hoang, VA Engel, L Wan, M Oh, R Sanishvili, ... BioRxiv, 676627, 2019 | 5 | 2019 |
Combating Parkinson’s disease-associated toxicity by modulating proteostasis Y Park, QQ Hoang Proceedings of the National Academy of Sciences 114 (5), 803-804, 2017 | 4 | 2017 |
Allosteric differences dictate GroEL complementation of E. coli J Sivinski, D Ngo, CJ Zerio, AJ Ambrose, ER Watson, LK Kaneko, ... FASEB journal: official publication of the Federation of American Societies …, 2022 | 1 | 2022 |
SMALL MOLECULE MODULATION OF HSP60/10 CHAPERONIN SYSTEMS: MORE COMMON THAN PREVIOUSLY THOUGHT? M Stevens, S Abdeen, N Salim, AM Ray, A Washburn, S Chitre, J Sivinski, ... PROTEIN SCIENCE 28, 112-113, 2019 | | 2019 |
Small-molecule modulation of HSP60/10 chaperonin systems: A therapeutic strategy over 100 years in the making? M Stevens, S Abdeen, AM Ray, A Washburn, S Chitre, J Sivinski, Y Park, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |