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P Benjamin Stranges
P Benjamin Stranges
Principal Scientist; GRO Biosciences
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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
P Mali, J Aach, PB Stranges, KM Esvelt, M Moosburner, S Kosuri, L Yang, ...
Nature biotechnology 31 (9), 833-838, 2013
22512013
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
L Wen, RE Ley, PY Volchkov, PB Stranges, L Avanesyan, AC Stonebraker, ...
Nature 455 (7216), 1109-1113, 2008
22122008
Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity
PB Stranges, J Watson, CJ Cooper, CM Choisy-Rossi, AC Stonebraker, ...
Immunity 26 (5), 629-641, 2007
3882007
Physical Principles for Scalable Neural Recording
AH Marblestone, BM Zamft, YG Maguire, MG Shapiro, TR Cybulski, ...
arXiv preprint arXiv:1306.5709, 2013
2972013
A comparison of successful and failed protein interface designs highlights the challenges of designing buried hydrogen bonds
PB Stranges, B Kuhlman
Protein Science 22 (1), 74-82, 2013
2092013
Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array
CW Fuller, S Kumar, M Porel, M Chien, A Bibillo, PB Stranges, M Dorwart, ...
Proceedings of the National Academy of Sciences 113 (19), 5233-5238, 2016
2002016
Community-wide assessment of protein-interface modeling suggests improvements to design methodology
SJ Fleishman, TA Whitehead, EM Strauch, JE Corn, S Qin, HX Zhou, ...
Journal of Molecular Biology, 2011
1562011
A Generic Program for Multistate Protein Design
A Leaver-Fay, R Jacak, PB Stranges, B Kuhlman
PloS one 6 (7), e20937, 2011
1122011
Computational design of a symmetric homodimer using β-strand assembly
PB Stranges, M Machius, MJ Miley, A Tripathy, B Kuhlman
Proceedings of the National Academy of Sciences, 2011
892011
Design and characterization of a nanopore-coupled polymerase for single-molecule DNA sequencing by synthesis on an electrode array
PB Stranges, M Palla, S Kalachikov, J Nivala, M Dorwart, S Kumar, ...
Proceedings of the National Academy of Sciences 113 (44), E6749-E6756, 2016
642016
Multiplex single-molecule kinetics of nanopore-coupled polymerases
M Palla, S Punthambaker, B Stranges, F Vigneault, J Nivala, D Wiegand, ...
Acs Nano 15 (1), 489-502, 2020
122020
Method and system of nanopore-based information encoding
GM Church, M Palla, PB Stranges, JM Nivala
US Patent 10,883,140, 2021
92021
Production of seleno-biologics in genomically recoded organisms
DJ Mandell, CJ Gregg, R Thyer, AD Ellington, PB Stranges
US Patent 11,492,650, 2022
52022
Non-standard amino acid containing compositions and uses thereof
DJ Mandell, CJ Gregg, PB Stranges
US Patent App. 18/154,231, 2023
2023
Non-standard amino acid containing compositions and uses thereof
DJ Mandell, CJ Gregg, PB Stranges
US Patent 11,584,921, 2023
2023
Enzyme screening methods
A Aruna, GM Church, M Palla, F Pepin, SSRA Punthambaker, ...
US Patent App. 16/798,064, 2020
2020
PRODUCTION OF SELENO-BIOLOGICALS IN GENETICALLY RECODED ORGANISMS
CJ GREGG, DJ MANDELL, R Thyer, AD Ellington, PB STRANGES
2020
Design of protein-protein interactions via β-strand pairing
PB Stranges
The University of North Carolina at Chapel Hill, 2012
2012
Polymer tagged nucleotides for single molecule DNA sequencing by synthesis on a nanopore array
S Kumar, M Porel, M Chien, C Tao, S Kalachikov, S Shi, M Palla, ...
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