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Woojin Won
Woojin Won
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Year
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2 production
H Chun, H Im, YJ Kang, Y Kim, JH Shin, W Won, J Lim, Y Ju, YM Park, ...
Nature neuroscience 23 (12), 1555-1566, 2020
1752020
Aberrant tonic inhibition of dopaminergic neuronal activity causes motor symptoms in animal models of Parkinson’s disease
JY Heo, MH Nam, HH Yoon, J Kim, YJ Hwang, W Won, DH Woo, JA Lee, ...
Current Biology 30 (2), 276-291. e9, 2020
882020
Activation of astrocytic μ-opioid receptor causes conditioned place preference
MH Nam, KS Han, J Lee, W Won, W Koh, JY Bae, J Woo, J Kim, E Kwong, ...
Cell reports 28 (5), 1154-1166. e5, 2019
872019
Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion
TY Kim, S Jeon, Y Jang, L Gotina, J Won, YH Ju, S Kim, MW Jang, W Won, ...
Experimental & molecular medicine 53 (5), 956-972, 2021
582021
Excessive astrocytic GABA causes cortical hypometabolism and impedes functional recovery after subcortical stroke
MH Nam, J Cho, DH Kwon, JY Park, J Woo, JM Lee, S Lee, HY Ko, ...
Cell reports 32 (1), 2020
522020
Visualizing reactive astrocyte-neuron interaction in Alzheimer’s disease using 11C-acetate and 18F-FDG
MH Nam, HY Ko, D Kim, S Lee, YM Park, SJ Hyeon, W Won, JI Chung, ...
Brain 146 (7), 2957-2974, 2023
172023
Signaling mechanisms of μ-opioid receptor (MOR) in the hippocampus: disinhibition versus astrocytic glutamate regulation
MH Nam, W Won, KS Han, CJ Lee
Cellular and Molecular Life Sciences 78, 415-426, 2021
172021
Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis
W Won, HJ Choi, JY Yoo, D Kim, TY Kim, YH Ju, KD Park, H Lee, SY Jung, ...
Experimental & Molecular Medicine 54 (8), 1188-1200, 2022
112022
Hypothalamic GABRA5-positive neurons control obesity via astrocytic GABA
M Sa, ES Yoo, W Koh, MG Park, HJ Jang, YR Yang, M Bhalla, JH Lee, ...
Nature Metabolism 5 (9), 1506-1525, 2023
92023
Adenovirus-induced reactive astrogliosis exacerbates the pathology of Parkinson’s disease
H An, H Lee, S Yang, W Won, CJ Lee, MH Nam
Experimental Neurobiology 30 (3), 222, 2021
92021
Platycodin D prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection in vitro by hindering membrane fusion
TY Kim, S Jeon, Y Jang, L Gotina, J Won, YH Ju, S Kim, MW Jang, W Won, ...
BioRxiv, 2020.12. 22.423909, 2020
62020
Visualization of reactive astrocytes in living brain of Alzheimer’s disease patient
MH Nam, HY Ko, S Lee, YM Park, SJ Hyeon, W Won, SY Kim, HH Jo, ...
BioRxiv, 2021.04. 13.439744, 2021
42021
Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
H Oh, S Lee, Y Oh, S Kim, YS Kim, Y Yang, W Choi, YE Yoo, H Cho, ...
Nature communications 14 (1), 3547, 2023
22023
Structure-guided engineering of a fast genetically encoded sensor for real-time H2O2 monitoring.
JD Lee, W Won, K Kimball, Y Wang, F Yeboah, K Evitts, C Neiswanger, ...
bioRxiv, 2024.01. 31.578117, 2024
12024
GABA from reactive astrocytes in hypothalamus via monoamine oxidase B causes and exacerbates obesity
M Sa, Y Yang, HJ Jang, J Kim, J Kwon, W Won, KD Park, CJ Lee
IBRO Reports 6, S126-S127, 2019
12019
Mao-b-dependent gaba in the hippocampal reactive astrocytic induces cognitive impairment in animal model of rheumatoid arthritis
W Won, SY Jung, CJ Lee
IBRO Reports 6, S330, 2019
12019
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via excessive H2O2-production
H Chun, Y Kim, YJ Kang, H Im, JH Shin, Y Ju, W Won, YM Park, J Lim, ...
IBRO Reports 6, S118, 2019
12019
Ultra-fast genetically encoded sensor for precise real-time monitoring of physiological and pathophysiological peroxide dynamics
A Berndt, J Lee, W Won, K Kimball, C Neiswanger, S Schattauer, Y Wang, ...
2024
Novel aminoaromatic compound or pharmaceutically acceptable salt thereof, and pharmaceutical composition for preventing or treating neurodegenerative diseases comprising same …
CJ Lee, C Heejung, WON Woojin, KD Park, JH Park, AN Pae, JW Choi, ...
US Patent App. 18/036,847, 2023
2023
Mapping Astrocytic and Neuronal μ-opioid Receptor Expression in Various Brain Regions Using MOR-mCherry Reporter Mouse
W Won, D Kim, E Shin, CJ Lee
Experimental Neurobiology 32 (6), 395, 2023
2023
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