| Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer Z Li, AC Bishop, M Alyamani, JA Garcia, R Dreicer, D Bunch, J Liu, ... Nature 523 (7560), 347-351, 2015 | 285 | 2015 |
| Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation Z Li, F Nie, S Wang, L Li Proceedings of the National Academy of Sciences 108 (8), 3116-3123, 2011 | 186 | 2011 |
| Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy Z Li, M Alyamani, J Li, K Rogacki, M Abazeed, SK Upadhyay, SP Balk, ... Nature 533 (7604), 547-551, 2016 | 167 | 2016 |
| Smurf1-mediated Lys29-linked nonproteolytic polyubiquitination of axin negatively regulates Wnt/β-catenin signaling C Fei, Z Li, C Li, Y Chen, Z Chen, X He, L Mao, X Wang, R Zeng, L Li Molecular and cellular biology 33 (20), 4095-4105, 2013 | 123 | 2013 |
| Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer J Li, M Alyamani, A Zhang, KH Chang, M Berk, Z Li, Z Zhu, M Petro, ... Elife 6, e20183, 2017 | 97 | 2017 |
| The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy G Wei, H Sun, K Dong, L Hu, Q Wang, Q Zhuang, Y Zhu, X Zhang, Y Shao, ... Cell metabolism 33 (10), 2021 | 53 | 2021 |
| Steroidogenic metabolism of galeterone reveals a diversity of biochemical activities M Alyamani, Z Li, M Berk, J Li, J Tang, S Upadhyay, RJ Auchus, N Sharifi Cell chemical biology 24 (7), 825-832. e6, 2017 | 50 | 2017 |
| Smad6 promotes neuronal differentiation in the intermediate zone of the dorsal neural tube by inhibition of the Wnt/β-catenin pathway Z Xie, Y Chen, Z Li, G Bai, Y Zhu, R Yan, F Tan, YG Chen, F Guillemot, ... Proceedings of the National Academy of Sciences 108 (29), 12119-12124, 2011 | 46 | 2011 |
| TAB2 scaffolds TAK1 and NLK in repressing canonical Wnt signaling M Li, H Wang, T Huang, J Wang, Y Ding, Z Li, J Zhang, L Li Journal of biological chemistry 285 (18), 13397-13404, 2010 | 44 | 2010 |
| Functional silencing of HSD17B2 in prostate cancer promotes disease progression X Gao, C Dai, S Huang, J Tang, G Chen, J Li, Z Zhu, X Zhu, S Zhou, ... Clinical Cancer Research 25 (4), 1291-1301, 2019 | 43 | 2019 |
| Loss of dihydrotestosterone-inactivation activity promotes prostate cancer castration resistance detectable by functional imaging Z Zhu, YM Chung, O Sergeeva, V Kepe, M Berk, J Li, HK Ko, Z Li, M Petro, ... Journal of Biological Chemistry 293 (46), 17829-17837, 2018 | 31 | 2018 |
| Development and validation of a novel LC–MS/MS method for simultaneous determination of abiraterone and its seven steroidal metabolites in human serum: Innovation in separation … M Alyamani, Z Li, SK Upadhyay, DJ Anderson, RJ Auchus, N Sharifi The Journal of steroid biochemistry and molecular biology 172, 231-239, 2017 | 31 | 2017 |
| Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism Y Han, Q Zhuang, B Sun, W Lv, S Wang, Q Xiao, B Pang, Y Zhou, F Wang, ... Nature Communications 12 (1), 449, 2021 | 27 | 2021 |
| Androgens in prostate cancer: A tale that never ends Z Hou, S Huang, Z Li Cancer Letters 516, 1-12, 2021 | 24 | 2021 |
| Inhibiting 3βHSD1 to eliminate the oncogenic effects of progesterone in prostate cancer Z Hou, S Huang, Z Mei, L Chen, J Guo, Y Gao, Q Zhuang, X Zhang, Q Tan, ... Cell Reports Medicine 3 (3), 2022 | 16 | 2022 |
| Management of prostate cancer by targeting 3βHSD1 after enzalutamide and abiraterone treatment Z Mei, T Yang, Y Liu, Y Gao, Z Hou, Q Zhuang, D He, X Zhang, Q Tan, ... Cell Reports Medicine 3 (5), 2022 | 12 | 2022 |
| Clinical significance of D4A in prostate cancer therapy with abiraterone H Emamekhoo, Z Li, N Sharifi Cell Cycle 14 (20), 3213-3214, 2015 | 12 | 2015 |
| Response of prostate cancer to addition of dutasteride after progression on abiraterone JP Lian, YY Gao, JJ Tang, X Chen, Y Liu, DL Wu, ZF Li, SS Huang Asian Journal of Andrology 23 (2), 222-223, 2021 | 8 | 2021 |
| Tracing steroidogenesis in prostate biopsy samples to unveil prostate tissue androgen metabolism characteristics and potential clinical application Z Hou, T Yang, Z Mei, S Zhang, Y Gao, X Chen, Q Tan, X Zhu, C Xu, ... The Journal of Steroid Biochemistry and Molecular Biology 210, 105859, 2021 | 7 | 2021 |
| Prospective role of 3βHSD1 in prostate cancer precision medicine Q Zhuang, S Huang, Z Li The Prostate 83 (7), 619-627, 2023 | 4 | 2023 |
