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Eszter Németh
Eszter Németh
Research Centre for Natural Sciences, Budapest
Verified email at ttk.hu
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Year
Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents
Á Póti, H Gyergyák, E Németh, O Rusz, S Tóth, C Kovácsházi, D Chen, ...
Genome biology 20, 1-13, 2019
942019
Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers
RA DeWeerd, E Németh, Á Póti, N Petryk, CL Chen, O Hyrien, D Szüts, ...
Cell reports 38 (12), 2022
312022
A comparative analysis of the mutagenicity of platinum-containing chemotherapeutic agents reveals direct and indirect mutagenic mechanisms
B Szikriszt, Á Póti, E Németh, N Kanu, C Swanton, D Szüts
Mutagenesis 36 (1), 75-86, 2021
232021
Two main mutational processes operate in the absence of DNA mismatch repair
E Németh, A Lovrics, JZ Gervai, M Seki, G Rospo, A Bardelli, D Szüts
DNA repair 89, 102827, 2020
182020
Precision-engineered reporter cell lines reveal ABCG2 regulation in live lung cancer cells
D Kovacsics, A Brózik, B Tihanyi, Z Matula, A Borsy, N Mészáros, E Szabó, ...
Biochemical Pharmacology 175, 113865, 2020
182020
The role of the N-terminal loop in the function of the colicin E7 nuclease domain
A Czene, E Németh, IG Zóka, NI Jakab-Simon, T Körtvélyesi, K Nagata, ...
JBIC Journal of Biological Inorganic Chemistry 18, 309-321, 2013
182013
BRCA1 deficiency specific base substitution mutagenesis is dependent on translesion synthesis and regulated by 53BP1
D Chen, JZ Gervai, Á Póti, E Németh, Z Szeltner, B Szikriszt, Z Gyüre, ...
Nature communications 13 (1), 226, 2022
172022
Design of a colicin E7 based chimeric zinc-finger nuclease
E Németh, GK Schilli, G Nagy, C Hasenhindl, B Gyurcsik, C Oostenbrink
Journal of Computer-Aided Molecular Design 28, 841-850, 2014
172014
Fine tuning of the catalytic activity of colicin E7 nuclease domain by systematic N‐terminal mutations
E Németh, T Körtvélyesi, PW Thulstrup, HEM Christensen, M Kožíšek, ...
Protein Science 23 (8), 1113-1122, 2014
142014
Preorganization of the catalytic Zn2+-binding site in the HNH nuclease motif—A solution study
E Németh, M Kožíšek, GK Schilli, B Gyurcsik
Journal of Inorganic Biochemistry 151, 143-149, 2015
132015
Substrate binding activates the designed triple mutant of the colicin E7 metallonuclease
E Németh, T Körtvélyesi, M Kožíšek, PW Thulstrup, HEM Christensen, ...
JBIC Journal of Biological Inorganic Chemistry 19, 1295-1303, 2014
92014
A study on the secondary structure of the metalloregulatory protein CueR: effect of pH, metal ions and DNA
RK Balogh, E Németh, NC Jones, SV Hoffmann, A Jancsó, B Gyurcsik
European Biophysics Journal 50 (3), 491-500, 2021
82021
Intrinsic protein disorder could be overlooked in cocrystallization conditions: An SRCD case study
E Németh, RK Balogh, K Borsos, A Czene, PW Thulstrup, B Gyurcsik
Protein Science 25 (11), 1977-1988, 2016
82016
A new insight into the zinc-dependent DNA-cleavage by the colicin E7 nuclease: a crystallographic and computational study
A Czene, E Tóth, E Németh, H Otten, JCN Poulsen, HEM Christensen, ...
Metallomics 6 (11), 2090-2099, 2014
72014
Spontaneous mutagenesis in human cells is controlled by REV1-Polymerase ζ and PRIMPOL
Z Gyüre, Á Póti, E Németh, B Szikriszt, R Lózsa, M Krawczyk, ...
Cell Reports 42 (8), 2023
62023
The genomic imprint of cancer therapies helps timing the formation of metastases
E Németh, M Krzystanek, L Reiniger, D Ribli, O Pipek, Z Sztupinszki, ...
International journal of cancer 145 (3), 694-704, 2019
52019
Chemical Approach to Biological Safety: Molecular‐Level Control of an Integrated Zinc Finger Nuclease
E Németh, MN Asaka, K Kato, Z Fábián, C Oostenbrink, HEM Christensen, ...
ChemBioChem 19 (1), 66-75, 2018
42018
Recent results in the development of genebank technologies specialized for medicinal plants.
E Tóth, É Németh
31996
Redesign of the Colicin E7 Nuclease domain into a controlled and specific artificial enzyme
E Németh
PQDT-Global, 2014
12014
DNA mismatch repair protects the genome from oxygen-induced replicative mutagenesis
R Lózsa, E Németh, JZ Gervai, BG Márkus, S Kollarics, Z Gyüre, J Tóth, ...
Nucleic Acids Research 51 (20), 11040-11055, 2023
2023
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