| Discovery and structure-activity relationship studies of 2-benzylidene-2, 3-dihydro-1H-inden-1-one and benzofuran-3 (2H)-one derivatives as a novel class of potential … TM Kadayat, S Banskota, P Gurung, G Bist, TBT Magar, A Shrestha, ... European Journal of Medicinal Chemistry 137, 575-597, 2017 | 44 | 2017 |
| Topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of dihydroxylated 2, 6-diphenyl-4-aryl pyridines R Karki, C Song, TM Kadayat, TBT Magar, G Bist, A Shrestha, Y Na, ... Bioorganic & medicinal chemistry 23 (13), 3638-3654, 2015 | 36 | 2015 |
| Inhibition of LPS-stimulated ROS production by fluorinated and hydroxylated chalcones in RAW 264.7 macrophages with structure-activity relationship study G Bist, NT Pun, TBT Magar, A Shrestha, HJ Oh, A Khakurel, PH Park, ... Bioorganic & medicinal chemistry letters 27 (5), 1205-1209, 2017 | 35 | 2017 |
| Rational design, synthesis, and evaluation of novel 2, 4-Chloro-and Hydroxy-Substituted diphenyl Benzofuro [3, 2-b] Pyridines: Non-intercalative catalytic topoisomerase I and … S Park, TBT Magar, TM Kadayat, HJ Lee, G Bist, A Shrestha, ES Lee, ... European Journal of Medicinal Chemistry 127, 318-333, 2017 | 31 | 2017 |
| Novel 2-aryl-4-(4′-hydroxyphenyl)-5H-indeno [1, 2-b] pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors S Park, TM Kadayat, KY Jun, TBT Magar, G Bist, A Shrestha, ES Lee, ... European journal of medicinal chemistry 125, 14-28, 2017 | 30 | 2017 |
| Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of 2-phenyl-or hydroxylated 2-phenyl-4-aryl-5H-indeno [1, 2-b … TM Kadayat, C Song, S Shin, TBT Magar, G Bist, A Shrestha, P Thapa, ... Bioorganic & Medicinal Chemistry 23 (13), 3499-3512, 2015 | 28 | 2015 |
| Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agents P Thapa, KY Jun, TM Kadayat, C Park, Z Zheng, TBT Magar, G Bist, ... Bioorganic & Medicinal Chemistry 23 (19), 6454-6466, 2015 | 26 | 2015 |
| Design, synthesis, and structure-activity relationships of new benzofuro [3, 2-b] pyridin-7-ols as DNA topoisomerase II inhibitors A Shrestha, H Jo, Y Kwon, ES Lee Bioorganic & Medicinal Chemistry Letters 28 (4), 566-571, 2018 | 25 | 2018 |
| Hydrophobic binding peptide-conjugated hybrid lipid-mesoporous silica nanoparticles for effective chemo-photothermal therapy of pancreatic cancer RK Thapa, HT Nguyen, M Gautam, A Shrestha, ES Lee, SK Ku, HG Choi, ... Drug Delivery 24 (1), 1690-1702, 2017 | 25 | 2017 |
| Synthesis and SAR study of new hydroxy and chloro-substituted 2, 4-diphenyl 5H-chromeno [4, 3-b] pyridines as selective topoisomerase IIα-targeting anticancer agents TBT Magar, SH Seo, TM Kadayat, H Jo, A Shrestha, G Bist, P Katila, ... Bioorganic & medicinal chemistry 26 (8), 1909-1919, 2018 | 24 | 2018 |
| Design, synthesis, and structure-activity relationship study of halogen containing 2-benzylidene-1-indanone derivatives for inhibition of LPS-stimulated ROS production in RAW … A Shrestha, HJ Oh, MJ Kim, NT Pun, TBT Magar, G Bist, H Choi, PH Park, ... European Journal of Medicinal Chemistry 133, 121-138, 2017 | 24 | 2017 |
| 2-Chlorophenyl-substituted benzofuro [3, 2-b] pyridines with enhanced topoisomerase inhibitory activity: The role of the chlorine substituent TBT Magar, TM Kadayat, HJ Lee, S Park, G Bist, A Shrestha, Y Kwon, ... Bioorganic & Medicinal Chemistry Letters 27 (15), 3279-3283, 2017 | 23 | 2017 |
| Discovery and Biological Evaluations of Halogenated 2,4-Diphenyl Indeno[1,2-b]pyridinol Derivatives as Potent Topoisomerase IIα-Targeted Chemotherapeutic … TM Kadayat, S Park, A Shrestha, H Jo, SY Hwang, P Katila, R Shrestha, ... Journal of Medicinal Chemistry 62 (17), 8194-8234, 2019 | 22 | 2019 |
| Dihydroxylated 2, 6-diphenyl-4-chlorophenylpyridines: Topoisomerase I and IIα dual inhibitors with DNA non-intercalative catalytic activity G Bist, S Park, C Song, TBT Magar, A Shrestha, Y Kwon, ES Lee European Journal of Medicinal Chemistry 133, 69-84, 2017 | 22 | 2017 |
| A novel indeno [1, 2-b] pyridinone derivative, a DNA intercalative human topoisomerase IIα catalytic inhibitor, for caspase 3-independent anticancer activity KH Jeon, C Park, TM Kadayat, A Shrestha, ES Lee, Y Kwon Chemical communications 53 (51), 6864-6867, 2017 | 21 | 2017 |
| A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study R Karki, KY Jun, TM Kadayat, S Shin, TBT Magar, G Bist, A Shrestha, ... European Journal of Medicinal Chemistry 113, 228-245, 2016 | 21 | 2016 |
| Design, synthesis, biological evaluation, structure-activity relationship study, and mode of action of 2-phenol-4, 6-dichlorophenyl-pyridines A Shrestha, S Park, S Shin, TM Kadayat, G Bist, P Katila, Y Kwon, ES Lee Bioorganic Chemistry 79, 1-18, 2018 | 16 | 2018 |
| Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents P Thapa, TM Kadayat, S Park, S Shin, TBT Magar, G Bist, A Shrestha, ... Bioorganic chemistry 66, 145-159, 2016 | 16 | 2016 |
| Effect of chlorine substituent on cytotoxic activities: Design and synthesis of systematically modified 2, 4-diphenyl-5H-indeno [1, 2-b] pyridines TM Kadayat, S Park, KY Jun, TBT Magar, G Bist, A Shrestha, Y Na, ... Bioorganic & Medicinal Chemistry Letters 26 (7), 1726-1731, 2016 | 16 | 2016 |
| Targeting peroxisome proliferator-activated receptor delta (PPARδ): a medicinal chemistry perspective TM Kadayat, A Shrestha, YH Jeon, H An, J Kim, SJ Cho, J Chin Journal of Medicinal Chemistry 63 (18), 10109-10134, 2020 | 15 | 2020 |
Tara Man Kadayat, Ph.D.Medicinal Chemist/Postdoctoral Scholar at University of Kentucky College of PharmacyVerified email at uky.edu
