Robotic fluidic coupling and interrogation of multiple vascularized organ chips R Novak, M Ingram, S Marquez, D Das, A Delahanty, A Herland, BM Maoz, ... Nature biomedical engineering 4 (4), 407-420, 2020 | 288 | 2020 |
Enhanced utilization of induced pluripotent stem cell–derived human intestinal organoids using microengineered chips MJ Workman, JP Gleeson, EJ Troisi, HQ Estrada, SJ Kerns, CD Hinojosa, ... Cellular and molecular gastroenterology and hepatology 5 (4), 669-677. e2, 2018 | 203 | 2018 |
Human iPSC-derived endothelial cells and microengineered organ-chip enhance neuronal development S Sances, R Ho, G Vatine, D West, A Laperle, A Meyer, M Godoy, PS Kay, ... Stem cell reports 10 (4), 1222-1236, 2018 | 145 | 2018 |
Human intestinal morphogenesis controlled by transepithelial morphogen gradient and flow-dependent physical cues in a microengineered gut-on-a-chip W Shin, CD Hinojosa, DE Ingber, HJ Kim IScience 15, 391-406, 2019 | 139 | 2019 |
Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption I Pediaditakis, KR Kodella, DV Manatakis, CY Le, CD Hinojosa, ... Nature communications 12 (1), 5907, 2021 | 107 | 2021 |
SEBS elastomers for fabrication of microfluidic devices with reduced drug absorption by injection molding and extrusion K Domansky, JD Sliz, N Wen, C Hinojosa, G Thompson, JP Fraser, ... Microfluidics and Nanofluidics 21, 1-12, 2017 | 72 | 2017 |
Low shear microfluidic devices and methods of use and manufacturing thereof DE Ingber, KH Benam, R Villenave, GA Hamilton, B Hassell, CD Hinojosa, ... US Patent 11,119,093, 2021 | 68 | 2021 |
Integrated human organ-on-chip microphysiological systems JP Wikswo, PC Samson, FE Block III, RS Reiserer, KK Parker, JA McLean, ... US Patent 9,725,687, 2017 | 60 | 2017 |
Organomimetic devices and methods of use and manufacturing thereof J Fernandez-alcon, N Wen, R Novak, DE Ingber, GA Hamilton, ... US Patent App. 15/105,388, 2016 | 57 | 2016 |
A novel organ-chip system emulates three-dimensional architecture of the human epithelia and the mechanical forces acting on it A Varone, JK Nguyen, L Leng, R Barrile, J Sliz, C Lucchesi, N Wen, ... Biomaterials 275, 120957, 2021 | 50 | 2021 |
Bone-chip system to monitor osteogenic differentiation using optical imaging D Sheyn, D Cohn-Yakubovich, S Ben-David, S De Mel, V Chan, ... Microfluidics and nanofluidics 23, 1-10, 2019 | 46 | 2019 |
Removing bubbles in microfluidic systems DE Ingber, GA Hamilton, D Levner, C Hinojosa, D Patterson US Patent 9,962,698, 2018 | 39 | 2018 |
Organs‐on‐chips in clinical pharmacology: putting the patient into the Center of Treatment Selection and Drug Development RW Peck, CD Hinojosa, GA Hamilton Clinical Pharmacology & Therapeutics 107 (1), 181-185, 2020 | 29 | 2020 |
Controlling pressure D Levner, JD Sliz, CD Hinojosa, J Gomes, J Fernandez-alcon US Patent 10,184,102, 2019 | 20 | 2019 |
A robotic platform for fluidically-linked human body-on-chips experimentation R Novak, M Ingram, S Clauson, D Das, A Delahanty, A Herland, BM Maoz, ... Nature biomedical engineering 4 (4), 407, 2020 | 18 | 2020 |
Membrane-based fluid-flow control devices G Thompson, D Levner, CD Hinojosa US Patent 10,086,372, 2018 | 18 | 2018 |
Droplet fluid connections D Levner, JD Sliz, CD Hinojosa, IIGR Thompson, PWM van Ruijven, ... US Patent 10,125,342, 2018 | 17 | 2018 |
A microengineered Brain-Chip to model neuroinflammation in humans I Pediaditakis, KR Kodella, DV Manatakis, CY Le, S Barthakur, A Sorets, ... Iscience 25 (8), 2022 | 15 | 2022 |
Interconnect Adaptor DE Ingber, CD Hinojosa, D Levner, JIN Resnikoff, G Thompson III US Patent App. 14/899,106, 2016 | 15 | 2016 |
Pressure manifold and culture module CD Hinojosa, IIGR Thompson, J Gomes, J Freake, D Sabin US Patent 10,233,416, 2019 | 13 | 2019 |