The heterochromatin protein 1 family G Lomberk, L Wallrath, R Urrutia Genome biology 7, 1-8, 2006 | 326 | 2006 |
Sin3: master scaffold and transcriptional corepressor A Grzenda, G Lomberk, JS Zhang, R Urrutia Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1789 (6-8 …, 2009 | 281 | 2009 |
Evidence for the existence of an HP1-mediated subcode within the histone code G Lomberk, D Bensi, ME Fernandez-Zapico, R Urrutia Nature cell biology 8 (4), 407-415, 2006 | 239 | 2006 |
The family feud: turning off Sp1 by Sp1-like KLF proteins G Lomberk, R Urrutia Biochemical Journal 392 (1), 1-11, 2005 | 236 | 2005 |
Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes G Lomberk, Y Blum, R Nicolle, A Nair, KS Gaonkar, L Marisa, A Mathison, ... Nature communications 9 (1), 1978, 2018 | 210 | 2018 |
Pancreatic adenocarcinoma therapeutic targets revealed by tumor-stroma cross-talk analyses in patient-derived xenografts R Nicolle, Y Blum, L Marisa, C Loncle, O Gayet, V Moutardier, O Turrini, ... Cell reports 21 (9), 2458-2470, 2017 | 163 | 2017 |
Inhibition of histone deacetylation potentiates the evolution of acquired temozolomide resistance linked to MGMT upregulation in glioblastoma xenografts GJ Kitange, AC Mladek, BL Carlson, MA Schroeder, JL Pokorny, L Cen, ... Clinical Cancer Research 18 (15), 4070-4079, 2012 | 155 | 2012 |
Kitlow stem cells cause resistance to Kit/platelet-derived growth factor α inhibitors in murine gastrointestinal stromal tumors MR Bardsley, VJ Horváth, DT Asuzu, A Lorincz, D Redelman, Y Hayashi, ... Gastroenterology 139 (3), 942-952, 2010 | 149 | 2010 |
Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis T Hamidi, H Algül, CE Cano, MJ Sandi, MI Molejon, M Riemann, EL Calvo, ... The Journal of clinical investigation 122 (6), 2092-2103, 2012 | 140 | 2012 |
Complementary vascular and matrix regulatory pathways underlie the beneficial mechanism of action of sorafenib in liver fibrosis D Thabut, C Routray, G Lomberk, U Shergill, K Glaser, R Huebert, L Patel, ... Hepatology 54 (2), 573-585, 2011 | 127 | 2011 |
Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein pathway in stress-induced monoamine oxidase A expression M Grunewald, S Johnson, D Lu, Z Wang, G Lomberk, PR Albert, ... Journal of Biological Chemistry 287 (29), 24195-24206, 2012 | 112 | 2012 |
IL17 functions through the novel REG3β–JAK2–STAT3 inflammatory pathway to promote the transition from chronic pancreatitis to pancreatic cancer C Loncle, L Bonjoch, E Folch-Puy, MB Lopez-Millan, S Lac, MI Molejon, ... Cancer research 75 (22), 4852-4862, 2015 | 110 | 2015 |
A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth ME Fernandez-Zapico, GA Lomberk, S Tsuji, CJ DeMars, MR Bardsley, ... Biochemical Journal 435 (2), 529-537, 2011 | 110 | 2011 |
Resolution of cochlear inflammation: novel target for preventing or ameliorating drug-, noise-and age-related hearing loss GM Kalinec, G Lomberk, RA Urrutia, F Kalinec Frontiers in cellular neuroscience 11, 192, 2017 | 106 | 2017 |
Insights into the epigenetic mechanisms controlling pancreatic carcinogenesis AL McCleary-Wheeler, GA Lomberk, FU Weiss, G Schneider, M Fabbri, ... Cancer letters 328 (2), 212-221, 2013 | 98 | 2013 |
Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes TM De Assuncao, Y Sun, N Jalan-Sakrikar, MC Drinane, BQ Huang, Y Li, ... Laboratory investigation 95 (6), 684-696, 2015 | 95 | 2015 |
Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production Y Guo, Y Fan, J Zhang, GA Lomberk, Z Zhou, L Sun, AJ Mathison, ... The Journal of clinical investigation 125 (10), 3819-3830, 2015 | 87 | 2015 |
Silencing of the transforming growth factor-β (TGFβ) receptor II by Krüppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFβ signaling MJ Truty, G Lomberk, ME Fernandez-Zapico, R Urrutia Journal of biological chemistry 284 (10), 6291-6300, 2009 | 86 | 2009 |
Disruption of a novel Krüppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal … A Bonnefond, G Lomberk, N Buttar, K Busiah, E Vaillant, S Lobbens, ... Journal of Biological Chemistry 286 (32), 28414-28424, 2011 | 84 | 2011 |
Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death T Hamidi, CE Cano, D Grasso, MN Garcia, MJ Sandi, EL Calvo, ... Clinical Cancer Research 18 (19), 5234-5246, 2012 | 80 | 2012 |