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Thomas Look
Thomas Look
Professor of Pediatrics, Harvard Medical School
Verified email at dfci.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
AP Weng, AA Ferrando, W Lee, JP Morris IV, LB Silverman, ...
Science 306 (5694), 269-271, 2004
33462004
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
SW Morris, MN Kirstein, MB Valentine, KG Dittmer, DN Shapiro, ...
Science 263 (5151), 1281-1284, 1994
27641994
Acute lymphoblastic leukaemia
CH Pui, LL Robison, AT Look
The Lancet 371 (9617), 1030-1043, 2008
22122008
The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1
CJ Sherr, CW Rettenmier, R Sacca, MF Roussel, AT Look, ER Stanley
Cell 41 (3), 665-676, 1985
18661985
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
P Niethammer, C Grabher, AT Look, TJ Mitchison
Nature 459 (7249), 996-999, 2009
17192009
Oncogenic transcription factors in the human acute leukemias
AT Look
Science 278 (5340), 1059-1064, 1997
15381997
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
AA Ferrando, DS Neuberg, J Staunton, ML Loh, C Huard, SC Raimondi, ...
Cancer cell 1 (1), 75-87, 2002
13062002
Human aminopeptidase N is a receptor for human coronavirus 229E
CL Yeager, RA Ashmun, RK Williams, CB Cardellichio, LH Shapiro, ...
Nature 357 (6377), 420-422, 1992
11301992
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
T Palomero, WK Lim, DT Odom, ML Sulis, PJ Real, A Margolin, ...
Proceedings of the National Academy of Sciences 103 (48), 18261-18266, 2006
10272006
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
T Teitz, T Wei, MB Valentine, EF Vanin, J Grenet, VA Valentine, FG Behm, ...
Nature medicine 6 (5), 529-535, 2000
10122000
Activating mutations in ALK provide a therapeutic target in neuroblastoma
RE George, T Sanda, M Hanna, S Fröhling, WL Ii, J Zhang, Y Ahn, ...
Nature 455 (7215), 975-978, 2008
10082008
An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
MR Mansour, BJ Abraham, L Anders, A Berezovskaya, A Gutierrez, ...
Science 346 (6215), 1373-1377, 2014
8432014
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
J O'Neil, J Grim, P Strack, S Rao, D Tibbitts, C Winter, J Hardwick, ...
The Journal of experimental medicine 204 (8), 1813-1824, 2007
7902007
Identification of breakpoints in t (8; 21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt
P Erickson, J Gao, KS Chang, T Look, E Whisenant, S Raimondi, ...
7641992
BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma
EE Patton, HR Widlund, JL Kutok, KR Kopani, JF Amatruda, RD Murphey, ...
Current Biology 15 (3), 249-254, 2005
7602005
Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study.
AT Look, FA Hayes, JJ Shuster, EC Douglass, RP Castleberry, ...
Journal of Clinical Oncology 9 (4), 581-591, 1991
7371991
The use of zebrafish to understand immunity
NS Trede, DM Langenau, D Traver, AT Look, LI Zon
Immunity 20 (4), 367-379, 2004
7302004
Chromosome 1p and 11q deletions and outcome in neuroblastoma
EF Attiyeh, WB London, YP Mossé, Q Wang, C Winter, D Khazi, ...
New England Journal of Medicine 353 (21), 2243-2253, 2005
7282005
tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors
S Berghmans, RD Murphey, E Wienholds, D Neuberg, JL Kutok, ...
Proceedings of the National Academy of Sciences 102 (2), 407-412, 2005
6832005
Evidence for an age cutoff greater than 365 days for neuroblastoma risk group stratification in the Children’s Oncology Group
WB London, RP Castleberry, KK Matthay, AT Look, RC Seeger, ...
J Clin Oncol 23 (27), 6459-65, 2005
6812005
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