David Chiron
David Chiron
CRCINA, INSERM, CNRS , Université de Nantes, Université d'Angers , Nantes , France.
Verified email at univ-nantes.fr - Homepage
Title
Cited by
Cited by
Year
Cell-Cycle Reprogramming for PI3K Inhibition Overrides a Relapse-Specific C481S BTK Mutation Revealed by Longitudinal Functional Genomics in Mantle Cell …
D Chiron, M Di Liberto, P Martin, X Huang, J Sharman, P Blecua, ...
Cancer discovery 4 (9), 1022-1035, 2014
251*2014
Toll-like receptors: lessons to learn from normal and malignant human B cells
D Chiron, I Bekeredjian-Ding, C Pellat-Deceunynck, R Bataille, G Jego
Blood, The Journal of the American Society of Hematology 112 (6), 2205-2213, 2008
1432008
TLR3 ligand induces NF-κB activation and various fates of multiple myeloma cells depending on IFN-α production
D Chiron, C Pellat-Deceunynck, M Amiot, R Bataille, G Jego
The Journal of Immunology 182 (7), 4471-4478, 2009
702009
Induction of prolonged early G1 arrest by CDK4/CDK6 inhibition reprograms lymphoma cells for durable PI3Kδ inhibition through PIK3IP1
D Chiron, P Martin, M Di Liberto, X Huang, S Ely, BJ Lannutti, JP Leonard, ...
Cell cycle 12 (12), 1892-1900, 2013
692013
Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma
D Chiron, C Dousset, C Brosseau, C Touzeau, S Maïga, P Moreau, ...
Oncotarget 6 (11), 8750, 2015
662015
Cell death via DR5, but not DR4, is regulated by p53 in myeloma cells
S Surget, D Chiron, P Gomez-Bougie, G Descamps, E Ménoret, R Bataille, ...
Cancer research 72 (17), 4562-4573, 2012
562012
Rational targeted therapies to overcome microenvironment-dependent expansion of mantle cell lymphoma
D Chiron, C Bellanger, A Papin, B Tessoulin, C Dousset, S Maiga, ...
Blood, The Journal of the American Society of Hematology 128 (24), 2808-2818, 2016
55*2016
p53 dysregulation in B-cell malignancies: More than a single gene in the pathway to hell
B Tessoulin, M Eveillard, A Lok, D Chiron, P Moreau, M Amiot, ...
Blood reviews 31 (4), 251-259, 2017
372017
Phosphorothioate-modified TLR9 ligands protect cancer cells against TRAIL-induced apoptosis
D Chiron, C Pellat-Deceunynck, M Maillasson, R Bataille, G Jego
The Journal of Immunology 183 (7), 4371-4377, 2009
372009
The peripheral CD138+ population but not the CD138-population contains myeloma clonogenic cells in plasma cell leukaemia patients.
D Chiron, S Surget, S Maïga, R Bataille, P Moreau, S Le Gouill, M Amiot, ...
British journal of haematology 156 (5), 679-683, 2011
332011
Critical role of the NOTCH ligand JAG2 in self-renewal of myeloma cells
D Chiron, S Maïga, G Descamps, P Moreau, S Le Gouill, S Marionneau, ...
Blood Cells, Molecules, and Diseases 48 (4), 247-253, 2012
322012
Autocrine insulin-like growth factor 1 and stem cell factor but not interleukin 6 support self-renewal of human myeloma cells
D Chiron, S Maiga, S Surget, G Descamps, P Gomez-Bougie, S Traore, ...
Blood cancer journal 3 (6), e120-e120, 2013
292013
BCL2-family dysregulation in B-cell malignancies: from gene expression regulation to a targeted therapy biomarker
B Tessoulin, A Papin, P Gomez-Bougie, C Bellanger, M Amiot, ...
Frontiers in oncology 8, 645, 2019
282019
TLR9 ligand induces the generation of CD20+ plasmablasts and plasma cells from CD27+ memory B-cells
A Geffroy-Luseau, D Chiron, G Descamps, G Jégo, M Amiot, ...
Frontiers in immunology 2, 83, 2011
282011
CSF1R and BTK inhibitions as novel strategies to disrupt the dialog between mantle cell lymphoma and macrophages
A Papin, B Tessoulin, C Bellanger, A Moreau, Y Le Bris, H Maisonneuve, ...
Leukemia 33 (10), 2442-2453, 2019
262019
Toll-like receptors: expression and involvement in multiple myeloma
D Chiron, G Jego, C Pellat-Deuceunynck
Leukemia research 34 (12), 1545-1550, 2010
242010
BH3 profiling as a tool to identify acquired resistance to venetoclax in multiple myeloma
C Dousset, S Maïga, P Gomez-Bougie, J Le Coq, C Touzeau, P Moreau, ...
British journal of haematology 179 (4), 684-688, 2017
212017
Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphoma
H Karvonen, D Chiron, W Niininen, S Ek, M Jerkeman, E Moradi, M Nykter, ...
Blood advances 1 (24), 2257-2268, 2017
202017
Pannexin‐1 limits the production of proinflammatory cytokines during necroptosis
T Douanne, G André‐Grégoire, K Trillet, A Thys, A Papin, M Feyeux, ...
EMBO reports 20 (10), e47840, 2019
152019
Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways
B Tessoulin, A Moreau-Aubry, G Descamps, P Gomez-Bougie, S Maïga, ...
Journal of hematology & oncology 11 (1), 1-13, 2018
152018
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