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Jung Youn-Sang
Jung Youn-Sang
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Wnt signaling in cancer: therapeutic targeting of Wnt signaling beyond β-catenin and the destruction complex
YS Jung, JI Park
Experimental & Molecular Medicine 52 (2), 183-191, 2020
2552020
Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function
SH Lee, SJ Lee, YS Jung, Y Xu, HS Kang, NC Ha, BJ Park
Neoplasia 11 (1), 22-IN6, 2009
1062009
LIG4 mediates Wnt signalling-induced radioresistance
S Jun, YS Jung, HN Suh, W Wang, MJ Kim, YS Oh, EM Lien, X Shen, ...
Nature communications 7 (1), 1-13, 2016
922016
Role of CK1 in GSK3β-mediated phosphorylation and degradation of snail
Y Xu, SH Lee, HS Kim, NH Kim, S Piao, SH Park, YS Jung, JI Yook, ...
Oncogene 29 (21), 3124-3133, 2010
832010
Interruption of progerin–lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype
SJ Lee, YS Jung, MH Yoon, S Kang, AY Oh, JH Lee, SY Jun, TG Woo, ...
The Journal of clinical investigation 126 (10), 3879-3893, 2016
732016
PAF-Wnt signaling-induced cell plasticity is required for maintenance of breast cancer cell stemness
X Wang, YS Jung, S Jun, S Lee, W Wang, A Schneider, Y Sun Oh, SH Lin, ...
Nature communications 7 (1), 1-13, 2016
682016
Wnt2 complements Wnt/β-catenin signaling in colorectal cancer
YS Jung, S Jun, SH Lee, A Sharma, JI Park
Oncotarget 6 (35), 37257, 2015
602015
TMEM9 promotes intestinal tumorigenesis through vacuolar-ATPase-activated Wnt/β-catenin signalling
YS Jung, S Jun, MJ Kim, SH Lee, HN Suh, EM Lien, HY Jung, S Lee, ...
Nature cell biology 20 (12), 1421-1433, 2018
512018
Antitumor effect of novel small chemical inhibitors of Snail-p53 binding in K-Ras-mutated cancer cells
SH Lee, GN Shen, YS Jung, SJ Lee, JY Chung, HS Kim, Y Xu, Y Choi, ...
Oncogene 29 (32), 4576-4587, 2010
442010
Direct interaction of α-synuclein and AKT regulates IGF-1 signaling: implication of Parkinson disease
JY Chung, SJ Lee, SH Lee, YS Jung, NC Ha, W Seol, BJ Park
Neurosignals 19 (2), 86-96, 2011
402011
Quiescence exit of tert+ stem cells by Wnt/β-catenin is indispensable for intestinal regeneration
HN Suh, MJ Kim, YS Jung, EM Lien, S Jun, JI Park
Cell reports 21 (9), 2571-2584, 2017
392017
Elevated TRAF2/6 expression in Parkinson’s disease is caused by the loss of Parkin E3 ligase activity
JY Chung, HR Park, SJ Lee, SH Lee, JS Kim, YS Jung, SH Hwang, ...
Laboratory investigation 93 (6), 663-676, 2013
382013
p53, secreted by K-Ras–Snail pathway, is endocytosed by K-Ras-mutated cells; implication of target-specific drug delivery and early diagnostic marker
SH Lee, SJ Lee, JY Chung, YS Jung, SY Choi, SH Hwang, D Choi, NC Ha, ...
Oncogene 28 (19), 2005-2014, 2009
372009
Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions
YS Jung, SJ Lee, MH Yoon, NC Ha, BJ Park
Cell cycle 11 (23), 4462-4473, 2012
362012
Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin
YS Jung, W Wang, S Jun, J Zhang, M Srivastava, MJ Kim, EM Lien, ...
Nature cell biology 20 (11), 1303-1314, 2018
352018
Novel tumor suppressive function of Smad4 in serum starvation-induced cell death through PAK1–PUMA pathway
SH Lee, YS Jung, JY Chung, AY Oh, SJ Lee, DH Choi, SM Jang, KS Jang, ...
Cell death & disease 2 (12), e235-e235, 2011
352011
Inhibiting DX2-p14/ARF interaction exerts antitumor effects in lung cancer and delays tumor progression
AY Oh, YS Jung, J Kim, JH Lee, JH Cho, HY Chun, S Park, H Park, S Lim, ...
Cancer Research 76 (16), 4791-4804, 2016
252016
TMEM9‐v‐ATPase activates Wnt/β‐catenin signaling via APC lysosomal degradation for liver regeneration and tumorigenesis
YS Jung, SA Stratton, SH Lee, MJ Kim, S Jun, J Zhang, B Zheng, ...
Hepatology 73 (2), 776-794, 2021
222021
Loss of VHL promotes progerin expression, leading to impaired p14/ARF function and suppression of p53 activity
YS Jung, SJ Lee, SH Lee, JY Chung, YJ Jung, SH Hwang, NC Ha, ...
Cell cycle 12 (14), 2277-2290, 2013
222013
Isolation of a chemical inhibitor against K-Ras-induced p53 suppression through natural compound screening
SJ Lee, YS Jung, SH Lee, HY Chung, BJ Park
International journal of oncology 34 (6), 1637-1643, 2009
222009
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