Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin J Park, SB Lee, S Lee, Y Kim, S Song, S Kim, E Bae, J Kim, M Shong, ... Nature 441 (7097), 1157-1161, 2006 | 1860 | 2006 |
Directly reprogrammed human neurons retain aging-associated transcriptomic signatures and reveal age-related nucleocytoplasmic defects J Mertens, ACM Paquola, M Ku, E Hatch, L Böhnke, S Ladjevardi, ... Cell stem cell 17 (6), 705-718, 2015 | 589 | 2015 |
Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation X Zheng, L Boyer, M Jin, J Mertens, Y Kim, L Ma, M Hamm, FH Gage, ... eLife 5, e13374, 2016 | 500 | 2016 |
Energy-dependent regulation of cell structure by AMP-activated protein kinase JH Lee, H Koh, M Kim, Y Kim, SY Lee, RE Karess, SH Lee, M Shong, ... Nature 447 (7147), 1017-1020, 2007 | 460 | 2007 |
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder J Mertens, QW Wang, Y Kim, DX Yu, S Pham, B Yang, Y Zheng, ... Nature 527 (7576), 95-99, 2015 | 459 | 2015 |
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation Y Kim, J Park, S Kim, S Song, SK Kwon, SH Lee, T Kitada, JM Kim, ... Biochemical and biophysical research communications 377 (3), 975-980, 2008 | 431 | 2008 |
Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia K Brennand, JN Savas, Y Kim, N Tran, A Simone, K Hashimoto-Torii, ... Molecular psychiatry 20 (3), 361-368, 2015 | 403 | 2015 |
Aging in a dish: iPSC-derived and directly induced neurons for studying brain aging and age-related neurodegenerative diseases J Mertens, D Reid, S Lau, Y Kim, FH Gage Annual review of genetics 52, 271-293, 2018 | 213 | 2018 |
ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase SB Lee, S Kim, J Lee, J Park, G Lee, Y Kim, JM Kim, J Chung EMBO reports 8 (4), 360-365, 2007 | 184 | 2007 |
Alleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegeneration X Zheng, L Boyer, M Jin, Y Kim, W Fan, C Bardy, T Berggren, RM Evans, ... eLife 5, e13378, 2016 | 128 | 2016 |
A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses D Sun, G Lee, JH Lee, HY Kim, HW Rhee, SY Park, KJ Kim, Y Kim, ... Nature structural & molecular biology 17 (10), 1188-1194, 2010 | 125 | 2010 |
Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons V Hook, KJ Brennand, Y Kim, T Toneff, L Funkelstein, KC Lee, M Ziegler, ... Stem cell reports 3 (4), 531-538, 2014 | 120 | 2014 |
Mitochondrial aging defects emerge in directly reprogrammed human neurons due to their metabolic profile Y Kim, X Zheng, Z Ansari, MC Bunnell, JR Herdy, L Traxler, H Lee, ... Cell reports 23 (9), 2550-2558, 2018 | 100 | 2018 |
Mitochondrial dysfunction and Parkinson’s disease genes: insights from Drosophila J Park, Y Kim, J Chung Disease models & mechanisms 2 (7-8), 336-340, 2009 | 73 | 2009 |
Drosophila Porin/VDAC Affects Mitochondrial Morphology J Park, Y Kim, S Choi, H Koh, SH Lee, JM Kim, J Chung PLOS one 5 (10), e13151, 2010 | 55 | 2010 |
Regulation of FOXO1 by TAK1-Nemo-like kinase pathway S Kim, Y Kim, J Lee, J Chung Journal of Biological Chemistry 285 (11), 8122-8129, 2010 | 50 | 2010 |
Chemical modulation of transcriptionally enriched signaling pathways to optimize conversion of fibroblasts into neurons J Herdy, S Schafer, Y Kim, Z Ansari, D Zangwill, M Ku, A Paquola, H Lee, ... eLife 8, e41356, 2019 | 42 | 2019 |
Mechanisms underlying the hyperexcitability of CA3 and dentate gyrus hippocampal neurons derived from patients with bipolar disorder S Stern, A Sarkar, T Stern, A Mei, APD Mendes, Y Stern, G Goldberg, ... Biological psychiatry 88 (2), 139-149, 2020 | 37 | 2020 |
Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease L Traxler, JR Herdy, D Stefanoni, S Eichhorner, S Pelucchi, A Szücs, ... Cell Metabolism 34 (9), 1248-1263. e6, 2022 | 35 | 2022 |
Simultaneous loss of TSC1 and DEPDC5 in skeletal and cardiac muscles produces early-onset myopathy and cardiac dysfunction associated with oxidative damage and SQSTM1/p62 … CS Cho, Y Kim, SR Park, B Kim, C Davis, I Hwang, SV Brooks, JH Lee, ... Autophagy 18 (10), 2303-2322, 2022 | 2 | 2022 |