Follow
Michael Pollastri
Michael Pollastri
Professor & Senior Vice Provost for Portland - Northeastern University
Verified email at northeastern.edu - Homepage
Title
Cited by
Cited by
Year
Overview on the Rule of Five
MP Pollastri
Current protocols in pharmacology 49 (1), 9.12. 1-9.12. 8, 2010
2372010
Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production
MM Lowe, JE Mold, B Kanwar, Y Huang, A Louie, MP Pollastri, C Wang, ...
PloS one 9 (2), e87877, 2014
1322014
The aryl hydrocarbon receptor is a critical regulator of tissue factor stability and an antithrombotic target in uremia
S Shivanna, K Kolandaivelu, M Shashar, M Belghasim, L Al-Rabadi, ...
Journal of the American Society of Nephrology 27 (1), 189-201, 2016
1072016
Repurposing strategies for tropical disease drug discovery
DM Klug, MH Gelb, MP Pollastri
Bioorganic & Medicinal Chemistry Letters 26 (11), 2569-2576, 2016
1052016
The susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposing
R Diaz-Gonzalez, FM Kuhlmann, C Galan-Rodriguez, LM da Silva, ...
PLoS neglected tropical diseases 5 (8), e1297, 2011
922011
Kinase scaffold repurposing for neglected disease drug discovery: Discovery of an efficacious, lapatanib-derived lead compound for trypanosomiasis
G Patel, CE Karver, R Behera, PJ Guyett, C Sullenberger, P Edwards, ...
Journal of medicinal chemistry 56 (10), 3820-3832, 2013
912013
Target repurposing for neglected diseases
MP Pollastri, RK Campbell
Future medicinal chemistry 3 (10), 1307-1315, 2011
892011
Ligand deconstruction: Why some fragment binding positions are conserved and others are not
D Kozakov, DR Hall, S Jehle, L Luo, SO Ochiana, EV Jones, M Pollastri, ...
Proceedings of the National Academy of Sciences 112 (20), E2585-E2594, 2015
802015
Kinases as druggable targets in trypanosomatid protozoan parasites
C Merritt, LE Silva, AL Tanner, K Stuart, MP Pollastri
Chemical reviews 114 (22), 11280-11304, 2014
752014
Antitrypanosomal lead discovery: identification of a ligand-efficient inhibitor of Trypanosoma cruzi CYP51 and parasite growth
G Andriani, E Amata, J Beatty, Z Clements, BJ Coffey, G Courtemanche, ...
Journal of medicinal chemistry 56 (6), 2556-2567, 2013
742013
2-Benzoylbenzoic acid: A photolabile mask for alcohols and thiols
PB Jones, MP Pollastri, NA Porter
The Journal of Organic Chemistry 61 (26), 9455-9461, 1996
661996
Protozoan parasite growth inhibitors discovered by cross-screening yield potent scaffolds for lead discovery
W Devine, JL Woodring, U Swaminathan, E Amata, G Patel, J Erath, ...
Journal of medicinal chemistry 58 (14), 5522-5537, 2015
652015
Loss of the tert-butyloxycarbonyl (Boc) protecting group under basic conditions
TP Curran, MP Pollastri, SM Abelleira, RJ Messier, TA McCollum, ...
Tetrahedron letters 35 (30), 5409-5412, 1994
641994
Calcium-Dependent Protein Kinase 5 Is Required for Release of Egress-Specific Organelles in Plasmodium falciparum
S Absalon, K Blomqvist, RM Rudlaff, TJ DeLano, MP Pollastri, JD Dvorin
MBio 9 (1), 10.1128/mbio. 00130-18, 2018
622018
Pharmacological validation of Trypanosoma brucei phosphodiesterases B1 and B2 as druggable targets for African sleeping sickness
ND Bland, C Wang, C Tallman, AE Gustafson, Z Wang, TD Ashton, ...
Journal of medicinal chemistry 54 (23), 8188-8194, 2011
622011
Fexinidazole: a new drug for African sleeping sickness on the horizon
MP Pollastri
Trends in parasitology 34 (3), 178-179, 2018
602018
Identification and Characterization of Hundreds of Potent and Selective Inhibitors of Trypanosoma brucei Growth from a Kinase-Targeted Library Screening …
R Diaz, SA Luengo-Arratta, JD Seixas, E Amata, W Devine, ...
PLoS Neglected Tropical Diseases 8 (10), e3253, 2014
592014
The future of drug repositioning: old drugs, new opportunities
TL Doan, M Pollastri, MA Walters, GI Georg
Annual reports in medicinal chemistry 46, 385-401, 2011
572011
Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery
G Patel, NE Roncal, PJ Lee, SE Leed, J Erath, A Rodriguez, RJ Sciotti, ...
MedChemComm 5 (5), 655-658, 2014
552014
The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing
SO Ochiana, V Pandarinath, Z Wang, R Kapoor, MJ Ondrechen, L Ruben, ...
European journal of medicinal chemistry 62, 777-784, 2013
532013
The system can't perform the operation now. Try again later.
Articles 1–20