Targeting of RAGE-ligand signaling impairs breast cancer cell invasion and metastasis T Kwak, K Drews-Elger, A Ergonul, PC Miller, A Braley, GH Hwang, ... Oncogene 36 (11), 1559-1572, 2017 | 138 | 2017 |
O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic β cells ES Kang, D Han, J Park, TK Kwak, MA Oh, SA Lee, S Choi, ZY Park, ... Experimental cell research 314 (11-12), 2238-2248, 2008 | 131 | 2008 |
Distinct populations of immune-suppressive macrophages differentiate from monocytic myeloid-derived suppressor cells in cancer T Kwak, F Wang, H Deng, T Condamine, V Kumar, M Perego, ... Cell reports 33 (13), 2020 | 119 | 2020 |
Blockade of four‐transmembrane L6 family member 5 (TM4SF5)‐mediated tumorigenicity in hepatocytes by a synthetic chalcone derivative SA Lee, HW Ryu, YM Kim, S Choi, MJ Lee, TK Kwak, HJ Kim, M Cho, ... Hepatology 49 (4), 1316-1325, 2009 | 72 | 2009 |
Cooperation between integrin α5 and tetraspan TM4SF5 regulates VEGF-mediated angiogenic activity S Choi, SA Lee, TK Kwak, HJ Kim, MJ Lee, SK Ye, SH Kim, S Kim, JW Lee Blood, The Journal of the American Society of Hematology 113 (8), 1845-1855, 2009 | 67 | 2009 |
Cross-talk between TGFβ1 and EGFR signalling pathways induces TM4SF5 expression and epithelial–mesenchymal transition M Kang, S Choi, SJ Jeong, SA Lee, TK Kwak, H Kim, O Jung, MS Lee, ... Biochemical Journal 443 (3), 691-700, 2012 | 66 | 2012 |
Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells O Jung, S Choi, SB Jang, SA Lee, ST Lim, YJ Choi, HJ Kim, DH Kim, ... Journal of cell science 125 (24), 5960-5973, 2012 | 58 | 2012 |
Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels SH Nam, D Kim, MS Lee, D Lee, TK Kwak, M Kang, J Ryu, HJ Kim, ... Oncotarget 6 (25), 21655, 2015 | 47 | 2015 |
Transmembrane 4 L six family member 5 (TM4SF5) enhances migration and invasion of hepatocytes for effective metastasis SA Lee, TY Kim, TK Kwak, H Kim, S Kim, HJ Lee, SH Kim, KH Park, ... Journal of cellular biochemistry 111 (1), 59-66, 2010 | 42 | 2010 |
Regulation of receptor for advanced glycation end products (RAGE) ectodomain shedding and its role in cell function A Braley, T Kwak, J Jules, E Harja, R Landgraf, BI Hudson Journal of Biological Chemistry 291 (23), 12057-12073, 2016 | 40 | 2016 |
The COOH-terminus of TM4SF5 in hepatoma cell lines regulates c-Src to form invasive protrusions via EGFR Tyr845 phosphorylation O Jung, YJ Choi, TK Kwak, M Kang, MS Lee, J Ryu, HJ Kim, JW Lee Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1833 (3), 629-642, 2013 | 36 | 2013 |
TM4SF5 accelerates G1/S phase progression via cytosolic p27Kip1 expression and RhoA activity H Kim, M Kang, SA Lee, TK Kwak, O Jung, HJ Lee, SH Kim, JW Lee Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1803 (8), 975-982, 2010 | 34 | 2010 |
The extracellular loop 2 of TM4SF5 inhibits integrin α2 on hepatocytes under collagen type I environment SA Lee, YM Kim, TK Kwak, HJ Kim, S Kim, W Ko, SH Kim, KH Park, ... Carcinogenesis 30 (11), 1872-1879, 2009 | 33 | 2009 |
BRAF targeting sensitizes resistant melanoma to cytotoxic T cells C Atay, T Kwak, S Lavilla-Alonso, L Donthireddy, A Richards, V Moberg, ... Clinical Cancer Research 25 (9), 2783-2794, 2019 | 30 | 2019 |
Cell adhesion-dependent serine 85 phosphorylation of paxillin modulates focal adhesion formation and haptotactic migration via association with the C-terminal tail domain of talin TK Kwak, MS Lee, J Ryu, YJ Choi, M Kang, D Jeong, JW Lee Journal of Biological Chemistry 287 (33), 27499-27509, 2012 | 28 | 2012 |
The effects of a randomized trial of brief forms of stress management on RAGE‐associated S100A8/A9 in patients with breast cancer undergoing primary treatment CJ Taub, ME Lippman, BI Hudson, BB Blomberg, A Diaz, HM Fisher, ... Cancer 125 (10), 1717-1725, 2019 | 25 | 2019 |
Differential inhibition of transmembrane 4 L six family member 5 (TM4SF5)-mediated tumorigenesis by TSAHC and sorafenib SA Lee, MS Lee, HW Ryu, TK Kwak, H Kim, M Kang, O Jung, HJ Kim, ... Cancer biology & therapy 11 (3), 330-336, 2011 | 19 | 2011 |
Glucosamine treatment-mediated O-GlcNAc modification of paxillin depends on adhesion state of rat insulinoma INS-1 cells TK Kwak, H Kim, O Jung, SA Lee, M Kang, HJ Kim, JM Park, SH Kim, ... Journal of biological chemistry 285 (46), 36021-36031, 2010 | 16 | 2010 |
ONP-302 nanoparticles inhibit tumor growth by altering tumor-associated macrophages and cancer-associated fibroblasts L Donthireddy, P Vonteddu, T Murthy, T Kwak, RN Eraslan, JR Podojil, ... Journal of Cancer 13 (6), 1933, 2022 | 6 | 2022 |
RAGE inhibitor TTP488 (Azeliragon) suppresses metastasis in triple-negative breast cancer M Magna, GH Hwang, A McIntosh, K Drews-Elger, M Takabatake, A Ikeda, ... Npj Breast Cancer 9 (1), 59, 2023 | 4 | 2023 |