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Taekyoung Kwak
Taekyoung Kwak
BostonGene Co.
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Targeting of RAGE-ligand signaling impairs breast cancer cell invasion and metastasis
T Kwak, K Drews-Elger, A Ergonul, PC Miller, A Braley, GH Hwang, ...
Oncogene 36 (11), 1559-1572, 2017
1382017
O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic β cells
ES Kang, D Han, J Park, TK Kwak, MA Oh, SA Lee, S Choi, ZY Park, ...
Experimental cell research 314 (11-12), 2238-2248, 2008
1312008
Distinct populations of immune-suppressive macrophages differentiate from monocytic myeloid-derived suppressor cells in cancer
T Kwak, F Wang, H Deng, T Condamine, V Kumar, M Perego, ...
Cell reports 33 (13), 2020
1192020
Blockade of four‐transmembrane L6 family member 5 (TM4SF5)‐mediated tumorigenicity in hepatocytes by a synthetic chalcone derivative
SA Lee, HW Ryu, YM Kim, S Choi, MJ Lee, TK Kwak, HJ Kim, M Cho, ...
Hepatology 49 (4), 1316-1325, 2009
722009
Cooperation between integrin α5 and tetraspan TM4SF5 regulates VEGF-mediated angiogenic activity
S Choi, SA Lee, TK Kwak, HJ Kim, MJ Lee, SK Ye, SH Kim, S Kim, JW Lee
Blood, The Journal of the American Society of Hematology 113 (8), 1845-1855, 2009
672009
Cross-talk between TGFβ1 and EGFR signalling pathways induces TM4SF5 expression and epithelial–mesenchymal transition
M Kang, S Choi, SJ Jeong, SA Lee, TK Kwak, H Kim, O Jung, MS Lee, ...
Biochemical Journal 443 (3), 691-700, 2012
662012
Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells
O Jung, S Choi, SB Jang, SA Lee, ST Lim, YJ Choi, HJ Kim, DH Kim, ...
Journal of cell science 125 (24), 5960-5973, 2012
582012
Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels
SH Nam, D Kim, MS Lee, D Lee, TK Kwak, M Kang, J Ryu, HJ Kim, ...
Oncotarget 6 (25), 21655, 2015
472015
Transmembrane 4 L six family member 5 (TM4SF5) enhances migration and invasion of hepatocytes for effective metastasis
SA Lee, TY Kim, TK Kwak, H Kim, S Kim, HJ Lee, SH Kim, KH Park, ...
Journal of cellular biochemistry 111 (1), 59-66, 2010
422010
Regulation of receptor for advanced glycation end products (RAGE) ectodomain shedding and its role in cell function
A Braley, T Kwak, J Jules, E Harja, R Landgraf, BI Hudson
Journal of Biological Chemistry 291 (23), 12057-12073, 2016
402016
The COOH-terminus of TM4SF5 in hepatoma cell lines regulates c-Src to form invasive protrusions via EGFR Tyr845 phosphorylation
O Jung, YJ Choi, TK Kwak, M Kang, MS Lee, J Ryu, HJ Kim, JW Lee
Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1833 (3), 629-642, 2013
362013
TM4SF5 accelerates G1/S phase progression via cytosolic p27Kip1 expression and RhoA activity
H Kim, M Kang, SA Lee, TK Kwak, O Jung, HJ Lee, SH Kim, JW Lee
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1803 (8), 975-982, 2010
342010
The extracellular loop 2 of TM4SF5 inhibits integrin α2 on hepatocytes under collagen type I environment
SA Lee, YM Kim, TK Kwak, HJ Kim, S Kim, W Ko, SH Kim, KH Park, ...
Carcinogenesis 30 (11), 1872-1879, 2009
332009
BRAF targeting sensitizes resistant melanoma to cytotoxic T cells
C Atay, T Kwak, S Lavilla-Alonso, L Donthireddy, A Richards, V Moberg, ...
Clinical Cancer Research 25 (9), 2783-2794, 2019
302019
Cell adhesion-dependent serine 85 phosphorylation of paxillin modulates focal adhesion formation and haptotactic migration via association with the C-terminal tail domain of talin
TK Kwak, MS Lee, J Ryu, YJ Choi, M Kang, D Jeong, JW Lee
Journal of Biological Chemistry 287 (33), 27499-27509, 2012
282012
The effects of a randomized trial of brief forms of stress management on RAGE‐associated S100A8/A9 in patients with breast cancer undergoing primary treatment
CJ Taub, ME Lippman, BI Hudson, BB Blomberg, A Diaz, HM Fisher, ...
Cancer 125 (10), 1717-1725, 2019
252019
Differential inhibition of transmembrane 4 L six family member 5 (TM4SF5)-mediated tumorigenesis by TSAHC and sorafenib
SA Lee, MS Lee, HW Ryu, TK Kwak, H Kim, M Kang, O Jung, HJ Kim, ...
Cancer biology & therapy 11 (3), 330-336, 2011
192011
Glucosamine treatment-mediated O-GlcNAc modification of paxillin depends on adhesion state of rat insulinoma INS-1 cells
TK Kwak, H Kim, O Jung, SA Lee, M Kang, HJ Kim, JM Park, SH Kim, ...
Journal of biological chemistry 285 (46), 36021-36031, 2010
162010
ONP-302 nanoparticles inhibit tumor growth by altering tumor-associated macrophages and cancer-associated fibroblasts
L Donthireddy, P Vonteddu, T Murthy, T Kwak, RN Eraslan, JR Podojil, ...
Journal of Cancer 13 (6), 1933, 2022
62022
RAGE inhibitor TTP488 (Azeliragon) suppresses metastasis in triple-negative breast cancer
M Magna, GH Hwang, A McIntosh, K Drews-Elger, M Takabatake, A Ikeda, ...
Npj Breast Cancer 9 (1), 59, 2023
42023
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