Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types HK Finucane, YA Reshef, V Anttila, K Slowikowski, A Gusev, A Byrnes, ... Nature genetics 50 (4), 621-629, 2018 | 872 | 2018 |
Single-cell chromatin state analysis with Signac T Stuart, A Srivastava, S Madad, CA Lareau, R Satija Nature methods 18 (11), 1333-1341, 2021 | 773* | 2021 |
Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations CP Fulco, J Nasser, TR Jones, G Munson, DT Bergman, V Subramanian, ... Nature genetics 51 (12), 1664-1669, 2019 | 672 | 2019 |
Chromatin potential identified by shared single-cell profiling of RNA and chromatin S Ma, B Zhang, LM LaFave, AS Earl, Z Chiang, Y Hu, J Ding, A Brack, ... Cell 183 (4), 1103-1116. e20, 2020 | 658 | 2020 |
Integrated single-cell analysis maps the continuous regulatory landscape of human hematopoietic differentiation JD Buenrostro, MR Corces, CA Lareau, B Wu, AN Schep, MJ Aryee, ... Cell 173 (6), 1535-1548. e16, 2018 | 631 | 2018 |
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors J Grünewald, R Zhou, SP Garcia, S Iyer, CA Lareau, MJ Aryee, JK Joung Nature 569 (7756), 433-437, 2019 | 538 | 2019 |
The polygenic and monogenic basis of blood traits and diseases D Vuckovic, EL Bao, P Akbari, CA Lareau, A Mousas, T Jiang, MH Chen, ... Cell 182 (5), 1214-1231.e14, 2020 | 432 | 2020 |
Lineage tracing in humans enabled by mitochondrial mutations and single-cell genomics LS Ludwig, CA Lareau, JC Ulirsch, E Christian, C Muus, LH Li, K Pelka, ... Cell 176 (6), 1325-1339. e22, 2019 | 410 | 2019 |
Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations MH Chen, LM Raffield, A Mousas, S Sakaue, JE Huffman, A Moscati, ... Cell 182 (5), 1198-1213. e14, 2020 | 405 | 2020 |
Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility CA Lareau, FM Duarte, JG Chew, VK Kartha, ZD Burkett, AS Kohlway, ... Nature Biotechnology 37 (8), 916-924, 2019 | 373 | 2019 |
The cis-regulatory atlas of the mouse immune system H Yoshida, CA Lareau, RN Ramirez, SA Rose, B Maier, A Wroblewska, ... Cell 176 (4), 897-912. e20, 2019 | 337* | 2019 |
A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation BC Michel, AR D’Avino, SH Cassel, N Mashtalir, ZM McKenzie, ... Nature cell biology 20 (12), 1410-1420, 2018 | 314 | 2018 |
The SARS-CoV-2 RNA–protein interactome in infected human cells N Schmidt, CA Lareau, H Keshishian, S Ganskih, C Schneider, T Hennig, ... Nature microbiology 6 (3), 339-353, 2021 | 289 | 2021 |
CRISPR DNA base editors with reduced RNA off-target and self-editing activities J Grünewald, R Zhou, S Iyer, CA Lareau, SP Garcia, MJ Aryee, JK Joung Nature biotechnology 37 (9), 1041-1048, 2019 | 286 | 2019 |
Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells EP Mimitou, CA Lareau, KY Chen, AL Zorzetto-Fernandes, Y Hao, ... Nature biotechnology 39 (10), 1246-1258, 2021 | 281 | 2021 |
Assessment of computational methods for the analysis of single-cell ATAC-seq data H Chen, C Lareau, T Andreani, ME Vinyard, SP Garcia, K Clement, ... Genome biology 20, 1-25, 2019 | 255 | 2019 |
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM H Chen, L Albergante, JY Hsu, CA Lareau, G Lo Bosco, J Guan, S Zhou, ... Nature communications 10 (1), 1-14, 2019 | 234 | 2019 |
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing J Grünewald, R Zhou, CA Lareau, SP Garcia, S Iyer, BR Miller, ... Nature Biotechnology 38 (7), 861-864, 2020 | 221 | 2020 |
Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling CA Lareau, LS Ludwig, C Muus, SH Gohil, T Zhao, Z Chiang, K Pelka, ... Nature biotechnology 39 (4), 451-461, 2021 | 179 | 2021 |
Interrogation of human hematopoiesis at single-cell and single-variant resolution JC Ulirsch, CA Lareau, EL Bao, LS Ludwig, MH Guo, C Benner, ... Nature genetics 51 (4), 683-693, 2019 | 178 | 2019 |