Núbia Boechat
Núbia Boechat
Tecnologista senior da Fundação Oswaldo Cruz
far.fiocruz.br의 이메일 확인됨
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Novel 1,2,3-Triazole Derivatives for Use against Mycobacterium tuberculosis H37Rv (ATCC 27294) Strain
N Boechat, VF Ferreira, SB Ferreira, MLG Ferreira, FC da Silva, ...
Journal of medicinal chemistry 54 (17), 5988-5999, 2011
2362011
Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1, 2, 3-triazole derivatives
MS Costa, N Boechat, EA Rangel, FC Da Silva, AMT De Souza, ...
Bioorganic & medicinal chemistry 14 (24), 8644-8653, 2006
2102006
Recently reported biological activities of pyrazole compounds
JV Faria, PF Vegi, AGC Miguita, MS Dos Santos, N Boechat, ...
Bioorganic & medicinal chemistry 25 (21), 5891-5903, 2017
1572017
The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication
CQ Sacramento, GR De Melo, CS De Freitas, N Rocha, LVB Hoelz, ...
Scientific reports 7 (1), 1-12, 2017
1532017
Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents
SB Ferreira, MS Costa, N Boechat, RJS Bezerra, MS Genestra, ...
European journal of medicinal chemistry 42 (11-12), 1388-1395, 2007
892007
Synthesis, antimalarial activity, and intracellular targets of MEFAS, a new hybrid compound derived from mefloquine and artesunate
F de Pilla Varotti, ACC Botelho, AA Andrade, RC de Paula, ...
Antimicrobial Agents and Chemotherapy 52 (11), 3868-3874, 2008
882008
Design, synthesis, and antiviral activity of new 1 H-1, 2, 3-triazole nucleoside ribavirin analogs
GF Maria de Lourdes, LCS Pinheiro, OA Santos-Filho, MDS Peçanha, ...
Medicinal Chemistry Research 23 (3), 1501-1511, 2014
692014
Novel 1H-1,2,3-, 2H-1,2,3-, 1H-1,2,4- and 4H-1,2,4-triazole derivatives: a patent review (2008 – 2011)
VF Ferreira, DR da Rocha, FC da Silva, PG Ferreira, NA Boechat, ...
Expert opinion on therapeutic patents 23 (3), 319-331, 2013
592013
A synthesis of 3-fluoroindoles and 3, 3-difluoroindolines by reduction of 3, 3-difluoro-2-oxindoles using a borane tetrahydrofuran complex
JC Torres, SJ Garden, AC Pinto, FSQ da Silva, N Boechat
Tetrahedron 55 (7), 1881-1892, 1999
581999
Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo
CS De Freitas, LM Higa, CQ Sacramento, AC Ferreira, PA Reis, ...
PLoS neglected tropical diseases 13 (1), e0007072, 2019
562019
New Compounds Hybrids 1H‐1,2,3‐Triazole‐Quinoline Against Plasmodium falciparum
N Boechat, MLG Ferreira, LCS Pinheiro, AML Jesus, MMM Leite, ...
Chemical biology & drug design 84 (3), 325-332, 2014
562014
New trifluoromethyl triazolopyrimidines as anti-Plasmodium falciparum agents
N Boechat, L Pinheiro, TS Silva, ACC Aguiar, AS Carvalho, MM Bastos, ...
Molecules 17 (7), 8285-8302, 2012
562012
Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication
AC Ferreira, PA Reis, CS de Freitas, CQ Sacramento, L Villas Bôas Hoelz, ...
Antimicrobial agents and chemotherapy 63 (2), e01389-18, 2019
522019
A simple reduction of methyl aromatic esters to alcohols using sodium borohydride–methanol system
N Boechat, JCS da Costa, J de Souza Mendonça, PSM de Oliveira, ...
Tetrahedron letters 45 (31), 6021-6022, 2004
492004
Design and synthesis of new N-(5-trifluoromethyl)-1H-1, 2, 4-triazol-3-yl benzenesulfonamides as possible antimalarial prototypes
N Boechat, L Pinheiro, OA Santos-Filho, IC Silva
Molecules 16 (9), 8083-8097, 2011
452011
Fluorodenitrations using tetramethylammonium fluoride
N Boechat, JH Clark
Journal of the Chemical Society, Chemical Communications, 921-922, 1993
441993
Design, synthesis and pharmacological evaluation of HIV-1 reverse transcriptase inhibition of new indolin-2-Ones
N Boechat, WB Kover, V Bongertz, MM Bastos, NC Romeiro, ...
Medicinal Chemistry 3 (6), 533-542, 2007
432007
Evaluation of 7-arylaminopyrazolo [1, 5-a] pyrimidines as anti-Plasmodium falciparum, antimalarial, and Pf-dihydroorotate dehydrogenase inhibitors
LFSP Azeredo, JP Coutinho, VAP Jabor, PR Feliciano, MC Nonato, ...
European journal of medicinal chemistry 126, 72-83, 2017
392017
Novel Selective Inhibitor of Leishmania (Leishmania) amazonensis Arginase
ER da Silva, N Boechat, LCS Pinheiro, MM Bastos, CCP Costa, ...
Chemical biology & drug design 86 (5), 969-978, 2015
392015
Laboratórios farmacêuticos oficiais e sua relevância para saúde pública do Brasil
JL de Magalhães
Revista Eletrônica de Comunicação, Informação e Inovação em Saúde 5 (1), 2011
392011
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