| Causal relationship between the loss of RUNX3 expression and gastric cancer QL Li, K Ito, C Sakakura, H Fukamachi, K Inoue, XZ Chi, KY Lee, ... Cell 109 (1), 113-124, 2002 | 1459 | 2002 |
| High levels of aberrant DNA methylation in Helicobacter pylori–infected gastric mucosae and its possible association with gastric cancer risk T Maekita, K Nakazawa, M Mihara, T Nakajima, K Yanaoka, M Iguchi, ... Clinical Cancer Research 12 (3), 989-995, 2006 | 686 | 2006 |
| Detection and interpretation of altered methylation patterns in cancer cells T Ushijima Nature Reviews Cancer 5 (3), 223-231, 2005 | 611 | 2005 |
| The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery HG Stunnenberg, S Abrignani, D Adams, M de Almeida, L Altucci, V Amin, ... Cell 167 (5), 1145-1149, 2016 | 508 | 2016 |
| Inflammatory Processes Triggered by Helicobacter pylori Infection Cause Aberrant DNA Methylation in Gastric Epithelial Cells T Niwa, T Tsukamoto, T Toyoda, A Mori, H Tanaka, T Maekita, M Ichinose, ... Cancer research 70 (4), 1430-1440, 2010 | 425 | 2010 |
| Inflammation-associated cancer development in digestive organs: mechanisms and roles for genetic and epigenetic modulation T Chiba, H Marusawa, T Ushijima Gastroenterology 143 (3), 550-563, 2012 | 409 | 2012 |
| Focus on gastric cancer T Ushijima, M Sasako Cancer cell 5 (2), 121-125, 2004 | 354 | 2004 |
| Epigenetic mechanisms of chronic pain G Descalzi, D Ikegami, T Ushijima, EJ Nestler, V Zachariou, M Narita Trends in neurosciences 38 (4), 237-246, 2015 | 345 | 2015 |
| DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: its possible involvement in the formation of epigenetic field defect T Ando, T Yoshida, S Enomoto, K Asada, M Tatematsu, M Ichinose, ... International Journal of Cancer 124 (10), 2367-2374, 2009 | 334 | 2009 |
| Hereditary diffuse gastric cancer: updated clinical practice guidelines VR Blair, M McLeod, F Carneiro, DG Coit, JL D'Addario, JM van Dieren, ... The Lancet Oncology 21 (8), e386-e397, 2020 | 303 | 2020 |
| Chemical genomic screening for methylation‐silenced genes in gastric cancer cell lines using 5‐aza‐2′‐deoxycytidine treatment and oligonucleotide microarray S Yamashita, Y Tsujino, K Moriguchi, M Tatematsu, T Ushijima Cancer science 97 (1), 64-71, 2006 | 297 | 2006 |
| Epigenetic field for cancerization T Ushijima BMB Reports 40 (2), 142-150, 2007 | 282 | 2007 |
| Silencing of the thrombomodulin gene in human malignant melanoma J Furuta, A Kaneda, Y Umebayashi, F Otsuka, T Sugimura, T Ushijima Melanoma Research 15 (1), 15-20, 2005 | 278 | 2005 |
| RUNX3 Suppresses Gastric Epithelial Cell Growth by Inducing p21WAF1/Cip1 Expression in Cooperation with Transforming Growth Factor β-Activated SMAD XZ Chi, JO Yang, KY Lee, K Ito, C Sakakura, QL Li, HR Kim, EJ Cha, ... Molecular and cellular biology 25 (18), 8097-8107, 2005 | 258 | 2005 |
| Establishment of methylation-sensitive–representational difference analysis and isolation of hypo-and hypermethylated genomic fragments in mouse liver tumors T Ushijima, K Morimura, Y Hosoya, H Okonogi, M Tatematsu, T Sugimura, ... Proceedings of the National Academy of Sciences 94 (6), 2284-2289, 1997 | 244 | 1997 |
| Cancer development based on chronic active gastritis and resulting gastric atrophy as assessed by serum levels of pepsinogen and Helicobacter pylori antibody titer T Yoshida, J Kato, I Inoue, N Yoshimura, H Deguchi, C Mukoubayashi, ... International journal of cancer 134 (6), 1445-1457, 2014 | 241 | 2014 |
| CpG island methylator phenotype is a strong determinant of poor prognosis in neuroblastomas M Abe, M Ohira, A Kaneda, Y Yagi, S Yamamoto, Y Kitano, T Takato, ... Cancer research 65 (3), 828-834, 2005 | 240 | 2005 |
| Silencing of Peroxiredoxin 2 and Aberrant Methylation of 33 CpG Islands in Putative Promoter Regions in Human Malignant Melanomas J Furuta, Y Nobeyama, Y Umebayashi, F Otsuka, K Kikuchi, T Ushijima Cancer research 66 (12), 6080-6086, 2006 | 235 | 2006 |
| Identification of silencing of nine genes in human gastric cancers A Kaneda, M Kaminishi, K Yanagihara, T Sugimura, T Ushijima Cancer research 62 (22), 6645-6650, 2002 | 226 | 2002 |
| Hippocampal epigenetic modification at the brain‐derived neurotrophic factor gene induced by an enriched environment N Kuzumaki, D Ikegami, R Tamura, N Hareyama, S Imai, M Narita, ... Hippocampus 21 (2), 127-132, 2011 | 224 | 2011 |
