Steven Paul Hanlon
Steven Paul Hanlon
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Identification of (S)-selective transaminases for the asymmetric synthesis of bulky chiral amines
IV Pavlidis, MS Weiß, M Genz, P Spurr, SP Hanlon, B Wirz, H Iding, ...
Nature chemistry 8 (11), 1076-1082, 2016
The use of enzymes in organic synthesis and the life sciences: perspectives from the Swiss Industrial Biocatalysis Consortium (SIBC)
HP Meyer, E Eichhorn, S Hanlon, S Lütz, M Schürmann, R Wohlgemuth, ...
Catalysis Science & Technology 3 (1), 29-40, 2013
Asymmetric reductive amination of ketones catalyzed by imine reductases
D Wetzl, M Gand, A Ross, H Müller, P Matzel, SP Hanlon, M Müller, B Wirz, ...
ChemCatChem 8 (12), 2023-2026, 2016
Expanding the imine reductase toolbox by exploring the bacterial protein‐sequence space
D Wetzl, M Berrera, N Sandon, D Fishlock, M Ebeling, M Müller, S Hanlon, ...
ChemBioChem 16 (12), 1749-1756, 2015
Rapid characterization of the major drug-metabolizing human hepatic cytochrome P-450 enzymes expressed in Escherichia coli
DF McGinnity, SJ Griffin, GC Moody, M Voice, S Hanlon, T Friedberg, ...
Drug metabolism and disposition 27 (9), 1017-1023, 1999
Isolation and characterization of a strain of Rhodobacter sulfidophilus: A bacterium which grows autotrophically with dimethylsulphide as electron donor
SP Hanlon, RA Holt, GR Moore, AG McEwan
Microbiology 140 (8), 1953-1958, 1994
Merits and limitations of recombinant models for the study of human P450-mediated drug metabolism and toxicity: an intralaboratory comparison
T Friedberg, MP Pritchard, M Bandera, SP Hanlon, D Yao, LA McLaughlin, ...
Drug metabolism reviews 31 (2), 523-544, 1999
Amine transaminase engineering for spatially bulky substrate acceptance
MS Weiß, IV Pavlidis, P Spurr, SP Hanlon, B Wirz, H Iding, ...
ChemBioChem 18 (11), 1022-1026, 2017
Human enzymes for organic synthesis
M Winkler, M Geier, SP Hanlon, B Nidetzky, A Glieder
Angewandte Chemie International Edition 57 (41), 13406-13423, 2018
Protein-engineering of an amine transaminase for the stereoselective synthesis of a pharmaceutically relevant bicyclic amine
MS Weiß, IV Pavlidis, P Spurr, SP Hanlon, B Wirz, H Iding, ...
Organic & biomolecular chemistry 14 (43), 10249-10254, 2016
The organic–synthetic potential of recombinant ene reductases: substrate‐scope evaluation and process optimization
T Reß, W Hummel, SP Hanlon, H Iding, H Gröger
ChemCatChem 7 (8), 1302-1311, 2015
Competition between cytochrome P-450 isozymes for NADPH-cytochrome P-450 oxidoreductase affects drug metabolism
DN Li, MP Pritchard, SP Hanlon, B Burchell, CR Wolf, T Friedberg
Journal of Pharmacology and Experimental Therapeutics 289 (2), 661-667, 1999
Expression of recombinant human flavin monooxygenase and moclobemide-N-oxide synthesis on multi-mg scale
SP Hanlon, A Camattari, S Abad, A Glieder, M Kittelmann, S Lütz, B Wirz, ...
Chemical communications 48 (48), 6001-6003, 2012
2-Phenylethylamine catabolism by Escherichia coli K-12: gene organization and expression
SP Hanlon, TK Hill, MA Flavell, JM Stringfellow, RA Cooper
Microbiology 143 (2), 513-518, 1997
Development of a Scalable Synthesis of (S)-3-Fluoromethyl-γ-butyrolactone, Building Block for Carmegliptin’s Lactam Moiety
JM Adam, J Foricher, S Hanlon, B Lohri, G Moine, R Schmid, H Stahr, ...
Organic Process Research & Development 15 (3), 515-526, 2011
Asymmetric reduction of racemic sulfoxides by dimethyl sulfoxide reductases from Rhodobacter capsulatus, Escherichia coli and Proteus species
SP Hanlon, DL Graham, PJ Hogan, RA Holt, CD Reeve, AL Shaw, ...
Microbiology 144 (8), 2247-2253, 1998
Dimethylsulfide:Acceptor Oxidoreductase from Rhodobacter sulfidophilus The Purified Enzyme Contains b ‐Type Haem and a Pterin Molybdenum Cofactor
SP Hanlon, TH Toh, PS Solomon, RA Holt, AG Mcewan
European journal of biochemistry 239 (2), 391-396, 1996
Biocatalysis in the fine chemical and pharmaceutical industries
PW Sutton, JP Adams, I Archer, D Auriol, M Avi, C Branneby, AJ Collis, ...
Practical methods for biocatalysis and biotransformations 2, 1-59, 2012
Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis
M Geier, T Bachler, SP Hanlon, FK Eggimann, M Kittelmann, H Weber, ...
Microbial cell factories 14, 1-10, 2015
The 44-kDa c-type cytochrome induced in Rhodobacter capsulatus during growth with dimethylsulphoxide as an electron acceptor is a cytochrome c peroxidase
SP Hanlon, RA Holt, AG McEwan
FEMS microbiology letters 97 (3), 283-287, 1992
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