Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor AR Dallosso, AL Hancock, M Szemes, K Moorwood, L Chilukamarri, ... PLoS genetics 5 (11), e1000745, 2009 | 171 | 2009 |
Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours AR Dallosso, AL Hancock, KW Brown, AC Williams, S Jackson, K Malik Human molecular genetics 13 (4), 405-415, 2004 | 113 | 2004 |
Multiple rare nonsynonymous variants in the adenomatous polyposis coli gene predispose to colorectal adenomas D Azzopardi, AR Dallosso, K Eliason, BC Hendrickson, N Jones, ... Cancer research 68 (2), 358-363, 2008 | 104 | 2008 |
Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways AR Dallosso, B Øster, A Greenhough, K Thorsen, TJ Curry, C Owen, ... Oncogene 31 (40), 4409-4419, 2012 | 103 | 2012 |
Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancer AR Dallosso, AL Hancock, S Malik, A Salpekar, L King-Underwood, ... Rna 13 (12), 2287-2299, 2007 | 87 | 2007 |
Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3 AR Dallosso, S Dolwani, N Jones, S Jones, J Colley, J Maynard, ... Gut 57 (9), 1252-1255, 2008 | 69 | 2008 |
Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors L Chilukamarri, AL Hancock, S Malik, J Zabkiewicz, JA Baker, ... Neoplasia 9 (11), 970-978, 2007 | 52 | 2007 |
Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A M Szemes, AR Dallosso, Z Melegh, T Curry, Y Li, C Rivers, J Uney, ... Human molecular genetics 22 (1), 74-83, 2013 | 51 | 2013 |
A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis AL Hancock, KW Brown, K Moorwood, H Moon, C Holmgren, SH Mardikar, ... Human molecular genetics 16 (3), 343-354, 2007 | 46 | 2007 |
Perilobar nephrogenic rests are nonobligate molecular genetic precursor lesions of insulin-like growth factor-II-associated Wilms tumors R Vuononvirta, NJ Sebire, AR Dallosso, JS Reis-Filho, RD Williams, ... Clinical Cancer Research 14 (23), 7635-7644, 2008 | 44 | 2008 |
The parathyroid hormone-responsive B1 gene is interrupted by at (1; 7)(q42; p15) breakpoint associated with Wilms' tumour EG Vernon, K Malik, P Reynolds, R Powlesland, AR Dallosso, S Jackson, ... Oncogene 22 (9), 1371-1380, 2003 | 40 | 2003 |
Genome‐wide DNA methylation analysis identifies MEGF10 as a novel epigenetically repressed candidate tumor suppressor gene in neuroblastoma J Charlet, A Tomari, AR Dallosso, M Szemes, M Kaselova, TJ Curry, ... Molecular Carcinogenesis 56 (4), 1290-1301, 2017 | 24 | 2017 |
Epigenetic deregulation of GATA3 in neuroblastoma is associated with increased GATA3 protein expression and with poor outcomes B Almutairi, J Charlet, AR Dallosso, M Szemes, HC Etchevers, KTA Malik, ... Scientific reports 9 (1), 18934, 2019 | 22 | 2019 |
Increased Efficacy of Histone Methyltransferase G9a Inhibitors Against MYCN-Amplified Neuroblastoma J Bellamy, M Szemes, Z Melegh, A Dallosso, M Kollareddy, D Catchpoole, ... Frontiers in oncology 10, 818, 2020 | 19 | 2020 |
Characterization of 17.94, a novel anaplastic Wilms' tumor cell line KW Brown, A Charles, A Dallosso, G White, J Charlet, GR Standen, ... Cancer genetics 205 (6), 319-326, 2012 | 16 | 2012 |
A human importin-β-related disorder: Syndromic thoracic aortic aneurysm caused by bi-allelic loss-of-function variants in IPO8 I Van Gucht, JAN Meester, JR Bento, M Bastiaansen, J Bastianen, ... The American Journal of Human Genetics 108 (6), 1115-1125, 2021 | 15 | 2021 |
Rapid recognition of aberrant dHPLC elution profiles using the Transgenomic NavigatorTM software J Colley, S Jones, AR Dallosso, JH Maynard, V Humphreys, S Dolwani, ... Human mutation 26 (2), 165-165, 2005 | 9 | 2005 |
The APC Variant p.Glu1317Gln predisposes to colorectal adenomas by a novel mechanism of relaxing the target for tumorigenic somatic APC mutations AR Dallosso, S Jones, D Azzopardi, V Moskvina, N Al‐Tassan, ... Human mutation 30 (10), 1412-1418, 2009 | 7 | 2009 |
Severe Congenital Myopathy and Neuropathy with Congenital Cataracts due to GFER Variant: A Neuropathological Study SB Sanchez-Marco, G Pierre, P Sharples, S Love, K Urankar, T Hilliard, ... Journal of Pediatric Neurology, 2022 | | 2022 |
The first human importin-beta-related disorder: syndromic thoracic aortic aneurysm caused by bi-allelic loss-of-function variants in IPO8 I Van Gucht, JAN Meester, JR Bento, M Bastiaansen, J Bastianen, ... EUROPEAN JOURNAL OF HUMAN GENETICS 30 (SUPPL 1), 5-6, 2022 | | 2022 |