Miniature multi-channel SPR instrument for methotrexate monitoring in clinical samples SS Zhao, N Bukar, JL Toulouse, D Pelechacz, R Robitaille, JN Pelletier, ... Biosensors and Bioelectronics 64, 664-670, 2015 | 152 | 2015 |
Fragment-based design of symmetrical bis-benzimidazoles as selective inhibitors of the trimethoprim-resistant, type II R67 dihydrofolate reductase D Bastien, MC Ebert, D Forge, J Toulouse, N Kadnikova, F Perron, ... Journal of Medicinal Chemistry 55 (7), 3182-3192, 2012 | 29 | 2012 |
Integron-associated DfrB4, a previously uncharacterized member of the trimethoprim-resistant dihydrofolate reductase B family, is a clinically identified emergent source of … JL Toulouse, TJ Edens, L Alejaldre, AR Manges, JN Pelletier Antimicrobial agents and chemotherapy 61 (5), 10.1128/aac. 02665-16, 2017 | 25 | 2017 |
Naked-eye nanobiosensor for therapeutic drug monitoring of methotrexate H Yockell-Lelièvre, N Bukar, JL Toulouse, JN Pelletier, JF Masson Analyst 141 (2), 697-703, 2016 | 25 | 2016 |
Transglutaminase-catalyzed bioconjugation using one-pot metal-free bioorthogonal chemistry NM Rachel, JL Toulouse, JN Pelletier Bioconjugate chemistry 28 (10), 2518-2523, 2017 | 23 | 2017 |
Dual-target inhibitors of the folate pathway inhibit intrinsically trimethoprim-resistant DfrB dihydrofolate reductases JL Toulouse, G Shi, C Lemay-St-Denis, MC Ebert, D Deon, M Gagnon, ... ACS medicinal chemistry letters 11 (11), 2261-2267, 2020 | 12 | 2020 |
Structure-based design of dimeric bisbenzimidazole inhibitors to an emergent trimethoprim-resistant type II dihydrofolate reductase guides the design of monomeric analogues JL Toulouse, BJ Yachnin, EH Ruediger, D Deon, M Gagnon, ... ACS omega 4 (6), 10056-10069, 2019 | 9 | 2019 |
Investigation of classical organic and ionic liquid cosolvents for early-stage screening in fragment-based inhibitor design with unrelated bacterial and human dihydrofolate … JL Toulouse, SMJ Abraham, N Kadnikova, D Bastien, V Gauchot, ... Assay and drug development technologies 15 (4), 141-153, 2017 | 3 | 2017 |
Découverte et optimisation d’inhibiteurs pour des enzymes DfrBs impliquées dans la résistance bactérienne J Toulouse | | 2019 |
Identification and optimization of inhibitors of dihydrofolate reductases B, trimethoprim-resistant enzymes J Toulouse, J Pelletier, D Bastien, D Forge, B Yachnin, D Deon, ... PROTEIN SCIENCE 26, 40-41, 2017 | | 2017 |
Developing a screening platform by Surface Plasmon Resonance (SPR) for the characterization and discovery of enzyme inhibitors SMJ Abraham, JL Toulouse, N Bukar, D Bastien, N Kadnikova, JF Masson, ... PROTEIN SCIENCE 26, 41-41, 2017 | | 2017 |