| Thioredoxin-interacting protein regulates insulin transcription through microRNA-204 G Xu, J Chen, G Jing, A Shalev Nature medicine 19 (9), 1141-1146, 2013 | 283 | 2013 |
| Preventing β-cell loss and diabetes with calcium channel blockers G Xu, J Chen, G Jing, A Shalev Diabetes 61 (4), 848-856, 2012 | 242 | 2012 |
| Verapamil and beta cell function in adults with recent-onset type 1 diabetes F Ovalle, T Grimes, G Xu, AJ Patel, TB Grayson, LA Thielen, P Li, ... Nature medicine 24 (8), 1108-1112, 2018 | 201 | 2018 |
| MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis SR Filios, G Xu, J Chen, K Hong, G Jing, A Shalev Journal of Biological Chemistry 289 (52), 36275-36283, 2014 | 105 | 2014 |
| FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells C Kibbe, J Chen, G Xu, G Jing, A Shalev Journal of Biological Chemistry 288 (32), 23194-23202, 2013 | 86 | 2013 |
| miR-204 controls glucagon-like peptide 1 receptor expression and agonist function SH Jo, J Chen, G Xu, TB Grayson, LA Thielen, A Shalev Diabetes 67 (2), 256-264, 2018 | 78 | 2018 |
| Identification of an anti-diabetic, orally available small molecule that regulates TXNIP expression and glucagon action LA Thielen, J Chen, G Jing, O Moukha-Chafiq, G Xu, SH Jo, TB Grayson, ... Cell metabolism 32 (3), 353-365. e8, 2020 | 71 | 2020 |
| Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2 G Jing, C Westwell-Roper, J Chen, G Xu, CB Verchere, A Shalev Journal of Biological Chemistry 289 (17), 11807-11815, 2014 | 66 | 2014 |
| Cytokines regulate β-cell thioredoxin-interacting protein (TXNIP) via distinct mechanisms and pathways K Hong, G Xu, TB Grayson, A Shalev Journal of Biological Chemistry 291 (16), 8428-8439, 2016 | 59 | 2016 |
| miR-204 targets PERK and regulates UPR signaling and β-cell apoptosis G Xu, J Chen, G Jing, TB Grayson, A Shalev Molecular endocrinology 30 (8), 917-924, 2016 | 57 | 2016 |
| Thioredoxin-interacting protein stimulates its own expression via a positive feedback loop J Chen, G Jing, G Xu, A Shalev Molecular Endocrinology 28 (5), 674-680, 2014 | 41 | 2014 |
| Islet ChREBP-β is increased in diabetes and controls ChREBP-α and glucose-induced gene expression via a negative feedback loop G Jing, J Chen, G Xu, A Shalev Molecular metabolism 5 (12), 1208-1215, 2016 | 40 | 2016 |
| Daxx interacts with HIV-1 integrase and inhibits lentiviral gene expression L Huang, G Xu, J Zhang, L Tian, J Xue, J Chen, W Jia Biochemical and biophysical research communications 373 (2), 241-245, 2008 | 38 | 2008 |
| Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes G Xu, TD Grimes, TB Grayson, J Chen, LA Thielen, HM Tse, P Li, M Kanke, ... Nature Communications 13 (1), 1159, 2022 | 36 | 2022 |
| DAXX interacts with phage ΦC31 integrase and inhibits recombination J Chen, C Ji, G Xu, R Pang, J Yao, H Zhu, J Xue, W Jia Nucleic acids research 34 (21), 6298-6304, 2006 | 35 | 2006 |
| Serum miR-204 is an early biomarker of type 1 diabetes-associated pancreatic beta-cell loss G Xu, LA Thielen, J Chen, TB Grayson, T Grimes, SL Bridges Jr, HM Tse, ... American Journal of Physiology-Endocrinology and Metabolism 317 (4), E723-E730, 2019 | 34 | 2019 |
| Calcium channel blockers act through nuclear factor Y to control transcription of key cardiac genes H Cha-Molstad, G Xu, J Chen, G Jing, ME Young, JC Chatham, A Shalev Molecular pharmacology 82 (3), 541-549, 2012 | 31 | 2012 |
| TTRAP is a novel PML nuclear bodies-associated protein G Xu, Y Pan, B Wang, L Huang, L Tian, J Xue, J Chen, W Jia Biochemical and biophysical research communications 375 (3), 395-398, 2008 | 22 | 2008 |
| Genetic analysis of the KIT and MC1R genes in Chinese indigenous pigs with belt-like coat color phenotypes. GL Xu, J Ren, NS Ding, HS Ai, YM Guo, CY Chen, LS Huang Animal Genetics 37 (5), 2006 | 18 | 2006 |
| ΦC31 integrase interacts with TTRAP and inhibits NFκB activation B Wang, G Xu, C Zhou, L Tian, J Xue, J Chen, W Jia Molecular biology reports 37, 2809-2816, 2010 | 14 | 2010 |
