Todd Brusko
Todd Brusko
Professor, University of Florida, Department of Pathology; Diabetes Institute - Research Director
Verified email at - Homepage
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A functional variant of SUMO4, a new IκBα modifier, is associated with type 1 diabetes
D Guo, M Li, Y Zhang, P Yang, S Eckenrode, D Hopkins, W Zheng, ...
Nature genetics 36 (8), 837-841, 2004
Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
CE Lowe, JD Cooper, T Brusko, NM Walker, DJ Smyth, R Bailey, ...
Nature genetics 39 (9), 1074-1082, 2007
Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse
MH Kapturczak, C Wasserfall, T Brusko, M Campbell-Thompson, TM Ellis, ...
The American journal of pathology 165 (3), 1045-1053, 2004
Human regulatory T cells: role in autoimmune disease and therapeutic opportunities
TM Brusko, AL Putnam, JA Bluestone
Immunological reviews 223 (1), 371-390, 2008
Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes
TM Brusko, CH Wasserfall, MJ Clare-Salzler, DA Schatz, MA Atkinson
Diabetes 54 (5), 1407-1414, 2005
Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes
SA McClymont, AL Putnam, MR Lee, JH Esensten, W Liu, MA Hulme, ...
The Journal of Immunology 186 (7), 3918-3926, 2011
Normalization of CD4+ T cell metabolism reverses lupus
Y Yin, SC Choi, Z Xu, DJ Perry, H Seay, BP Croker, ES Sobel, TM Brusko, ...
Science translational medicine 7 (274), 274ra18-274ra18, 2015
Expansion of human regulatory T-cells from patients with type 1 diabetes
AL Putnam, TM Brusko, MR Lee, W Liu, GL Szot, T Ghosh, MA Atkinson, ...
Diabetes 58 (3), 652-662, 2009
No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes
T Brusko, C Wasserfall, K McGrail, R Schatz, HL Viener, D Schatz, ...
Diabetes 56 (3), 604-612, 2007
Autologous umbilical cord blood infusion for type 1 diabetes
MJ Haller, HL Viener, C Wasserfall, T Brusko, MA Atkinson, DA Schatz
Experimental hematology 36 (6), 710-715, 2008
Radial artery tonometry demonstrates arterial stiffness in children with type 1 diabetes
MJ Haller, M Samyn, WW Nichols, T Brusko, C Wasserfall, RF Schwartz, ...
Diabetes care 27 (12), 2911-2917, 2004
Systemic overexpression of IL-10 induces CD4+ CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion
KS Goudy, BR Burkhardt, C Wasserfall, S Song, ML Campbell-Thompson, ...
The Journal of Immunology 171 (5), 2270-2278, 2003
An integral role for heme oxygenase-1 and carbon monoxide in maintaining peripheral tolerance by CD4+ CD25+ regulatory T cells
TM Brusko, CH Wasserfall, A Agarwal, MH Kapturczak, MA Atkinson
The Journal of Immunology 174 (9), 5181-5186, 2005
Increased natural CD4+ CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis
PO Scumpia, MJ Delano, KM Kelly, KA O’Malley, PA Efron, PF McAuliffe, ...
The Journal of Immunology 177 (11), 7943-7949, 2006
Divergent phenotypes of human regulatory T cells expressing the receptors TIGIT and CD226
CA Fuhrman, WI Yeh, HR Seay, PS Lakshmi, G Chopra, L Zhang, ...
The Journal of Immunology 195 (1), 145-155, 2015
Human antigen-specific regulatory T cells generated by T cell receptor gene transfer
TM Brusko, RC Koya, S Zhu, MR Lee, AL Putnam, SA McClymont, ...
PloS one 5 (7), e11726, 2010
Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells
TN Golovina, T Mikheeva, TM Brusko, BR Blazar, JA Bluestone, JL Riley
PloS one 6 (1), e15868, 2011
Suppression by CD4+ CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cells
JF George, A Braun, TM Brusko, R Joseph, S Bolisetty, CH Wasserfall, ...
The American journal of pathology 173 (1), 154-160, 2008
Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice
YC Zhang, A Pileggi, A Agarwal, RD Molano, M Powers, T Brusko, ...
Diabetes 52 (3), 708-716, 2003
Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes
MJ Haller, SE Gitelman, PA Gottlieb, AW Michels, SM Rosenthal, ...
The Journal of clinical investigation 125 (1), 448-455, 2015
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