Srinivas Somarowthu
Srinivas Somarowthu
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HOTAIR forms an intricate and modular secondary structure
S Somarowthu, M Legiewicz, I Chillón, M Marcia, F Liu, AM Pyle
Molecular cell 58 (2), 353-361, 2015
Visualizing the secondary and tertiary architectural domains of lncRNA RepA
F Liu, S Somarowthu, AM Pyle
Nature chemical biology 13 (3), 282, 2017
Now on display: a gallery of group II intron structures at different stages of catalysis
M Marcia, S Somarowthu, AM Pyle
Mobile DNA 4 (1), 1-14, 2013
High‐performance prediction of functional residues in proteins with machine learning and computed input features
S Somarowthu, H Yang, DGC Hildebrand, MJ Ondrechen
Biopolymers 95 (6), 390-400, 2011
A tale of two isomerases: compact versus extended active sites in ketosteroid isomerase and phosphoglucose isomerase
S Somarowthu, HR Brodkin, JA D’Aquino, D Ringe, MJ Ondrechen, ...
Biochemistry 50 (43), 9283-9295, 2011
POOL server: machine learning application for functional site prediction in proteins
S Somarowthu, MJ Ondrechen
Bioinformatics 28 (15), 2078-2079, 2012
Native purification and analysis of long RNAs
I Chillón, M Marcia, M Legiewicz, F Liu, S Somarowthu, AM Pyle
Methods in enzymology 558, 3-37, 2015
Phylogenetic analysis with improved parameters reveals conservation in lncRNA structures
RCA Tavares, AM Pyle, S Somarowthu
Journal of molecular biology 431 (8), 1592-1603, 2019
Prediction of distal residue participation in enzyme catalysis
HR Brodkin, NA DeLateur, S Somarowthu, CL Mills, WR Novak, ...
Protein Science 24 (5), 762-778, 2015
Protein function annotation with structurally aligned local sites of activity (SALSAs)
Z Wang, P Yin, JS Lee, R Parasuram, S Somarowthu, MJ Ondrechen
BMC bioinformatics 14 (S3), S13, 2013
Functional classification of protein 3D structures from predicted local interaction sites
R Parasuram, JS Lee, P Yin, S Somarowthu, MJ Ondrechen
Journal of Bioinformatics and Computational Biology 8 (supp01), 1-15, 2010
Visualizing the ai5γ group IIB intron
S Somarowthu, M Legiewicz, KS Keating, AM Pyle
Nucleic acids research 42 (3), 1947-1958, 2014
Solving nucleic acid structures by molecular replacement: examples from group II intron studies
M Marcia, E Humphris-Narayanan, KS Keating, S Somarowthu, ...
Acta Crystallographica Section D: Biological Crystallography 69 (11), 2174-2185, 2013
Crystal structure of a metal‐dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation …
GW Han, J Ko, CL Farr, MC Deller, Q Xu, HJ Chiu, MD Miller, J Sefcikova, ...
Proteins: Structure, Function, and Bioinformatics 79 (7), 2146-2160, 2011
Progress and current challenges in modeling large RNAs
S Somarowthu
Journal of molecular biology 428 (5), 736-747, 2016
Identifying structural domains and conserved regions in the long non-coding RNA lncTCF7
MC Owens, SC Clark, A Yankey, S Somarowthu
International journal of molecular sciences 20 (19), 4770, 2019
Visualizing group II intron dynamics between the first and second steps of splicing
J Manigrasso, I Chillón, V Genna, P Vidossich, S Somarowthu, AM Pyle, ...
Nature Communications 11 (1), 1-15, 2020
Xist attenuates acute inflammatory response by female cells
BB Shenoda, S Ramanathan, R Gupta, Y Tian, R Jean-Toussaint, ...
Cellular and Molecular Life Sciences, 1-18, 2020
Prediction and experimental verification of compact versus extended enzyme active sites: a tale of two isomerases
S Somarowthu
Replication protein A binds RNA and promotes R-loop formation
OM Mazina, S Somarowthu, LY Kadyrova, AG Baranovskiy, TH Tahirov, ...
bioRxiv, 2020
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