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Wade Winkler
Wade Winkler
Department of Cell Biology and Molecular Biology, University of Maryland
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Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression
W Winkler, A Nahvi, RR Breaker
Nature 419 (6910), 952-956, 2002
15512002
Control of gene expression by a natural metabolite-responsive ribozyme
WC Winkler, A Nahvi, A Roth, JA Collins, RR Breaker
Nature 428 (6980), 281-286, 2004
11762004
Regulation of bacterial gene expression by riboswitches
WC Winkler, RR Breaker
Annu. Rev. Microbiol. 59, 487-517, 2005
9272005
Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria
M Mandal, B Boese, JE Barrick, WC Winkler, RR Breaker
cell 113 (5), 577-586, 2003
9142003
An mRNA structure that controls gene expression by binding FMN
WC Winkler, S Cohen-Chalamish, RR Breaker
Proceedings of the National Academy of Sciences 99 (25), 15908-15913, 2002
8242002
New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control
JE Barrick, KA Corbino, WC Winkler, A Nahvi, M Mandal, J Collins, M Lee, ...
Proceedings of the National Academy of Sciences 101 (17), 6421-6426, 2004
5902004
An mRNA structure that controls gene expression by binding S-adenosylmethionine
WC Winkler, A Nahvi, N Sudarsan, JE Barrick, RR Breaker
Nature Structural & Molecular Biology 10 (9), 701-707, 2003
5512003
The speed of RNA transcription and metabolite binding kinetics operate an FMN riboswitch
JK Wickiser, WC Winkler, RR Breaker, DM Crothers
Molecular cell 18 (1), 49-60, 2005
5392005
Structure and mechanism of a metal-sensing regulatory RNA
CE Dann, CA Wakeman, CL Sieling, SC Baker, I Irnov, WC Winkler
Cell 130 (5), 878-892, 2007
4312007
Genetic control by metabolite‐binding riboswitches
WC Winkler, RR Breaker
Chembiochem 4 (10), 1024-1032, 2003
3902003
Glu-tRNAGln amidotransferase: A novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation
AW Curnow, K Hong, R Yuan, S Kim, O Martins, W Winkler, TM Henkin, ...
Proceedings of the National Academy of Sciences 94 (22), 11819-11826, 1997
3881997
Mechanism of mRNA destabilization by the glmS ribozyme
JA Collins, I Irnov, S Baker, WC Winkler
Genes & development 21 (24), 3356-3368, 2007
3162007
A riboswitch selective for the queuosine precursor preQ1 contains an unusually small aptamer domain
A Roth, WC Winkler, EE Regulski, BWK Lee, J Lim, I Jona, JE Barrick, ...
Nature structural & molecular biology 14 (4), 308-317, 2007
2972007
Identification of regulatory RNAs in Bacillus subtilis
I Irnov, CM Sharma, J Vogel, WC Winkler
Nucleic acids research 38 (19), 6637-6651, 2010
2362010
Bacterial riboswitches cooperatively bind Ni2+ or Co2+ ions and control expression of heavy metal transporters
K Furukawa, A Ramesh, Z Zhou, Z Weinberg, T Vallery, WC Winkler, ...
Molecular cell 57 (6), 1088-1098, 2015
1712015
Riboswitches and the role of noncoding RNAs in bacterial metabolic control
WC Winkler
Current opinion in chemical biology 9 (6), 594-602, 2005
1632005
tRNA-mediated transcription antitermination in vitro: codon–anticodon pairing independent of the ribosome
FJ Grundy, WC Winkler, TM Henkin
Proceedings of the National Academy of Sciences 99 (17), 11121-11126, 2002
1492002
A riboswitch-containing sRNA controls gene expression by sequestration of a response regulator
S DebRoy, M Gebbie, A Ramesh, JR Goodson, MR Cruz, A Van Hoof, ...
Science 345 (6199), 937-940, 2014
1472014
The GA motif: an RNA element common to bacterial antitermination systems, rRNA, and eukaryotic RNAs.
WC Winkler, FJ Grundy, BA Murphy, TM Henkin
Rna 7 (8), 1165-1172, 2001
1422001
Expanding roles for metabolite-sensing regulatory RNAs
MD Dambach, WC Winkler
Current opinion in microbiology 12 (2), 161-169, 2009
1342009
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