Astrocytes control sensory acuity via tonic inhibition in the thalamus H Kwak, W Koh, S Kim, K Song, JI Shin, JM Lee, EH Lee, JY Bae, GE Ha, ... Neuron 108 (4), 691-706. e10, 2020 | 75 | 2020 |
(1S, 3S)-3-Amino-4-difluoromethylenyl-1-cyclopentanoic Acid (CPP-115), a Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Cocaine … Y Pan, MR Gerasimov, T Kvist, P Wellendorph, KK Madsen, E Pera, H Lee, ... Journal of medicinal chemistry 55 (1), 357-366, 2012 | 54 | 2012 |
Suppression of hepatocellular carcinoma by inhibition of overexpressed ornithine aminotransferase E Zigmond, AB Ya’acov, H Lee, Y Lichtenstein, Z Shalev, Y Smith, ... ACS medicinal chemistry letters 6 (8), 840-844, 2015 | 47 | 2015 |
Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer’s disease YH Ju, M Bhalla, SJ Hyeon, JE Oh, S Yoo, U Chae, J Kwon, W Koh, J Lim, ... Cell Metabolism 34 (8), 1104-1120. e8, 2022 | 42 | 2022 |
Synthesis and evaluation of a new bifunctional NETA chelate for molecular targeted radiotherapy using90Y or177Lu CS Kang, Y Chen, H Lee, D Liu, X Sun, J Kweon, MR Lewis, HS Chong Nuclear medicine and biology 42 (3), 242-249, 2015 | 41 | 2015 |
Quantitative profiling of bile acids in rat bile using ultrahigh-performance liquid chromatography–orbitrap mass spectrometry: Alteration of the bile acid composition with aging G Lee, H Lee, J Hong, SH Lee, BH Jung Journal of Chromatography B 1031, 37-49, 2016 | 40 | 2016 |
Regulation of endogenic metabolites by rosuvastatin in hyperlipidemia patients: An integration of metabolomics and lipidomics H Lee, JM Choi, JY Cho, TE Kim, HJ Lee, BH Jung Chemistry and physics of lipids 214, 69-83, 2018 | 38 | 2018 |
Ornithine aminotransferase versus GABA aminotransferase: implications for the design of new anticancer drugs H Lee, JI Juncosa, RB Silverman Medicinal research reviews 35 (2), 286-305, 2015 | 38 | 2015 |
Mechanism of Inactivation of γ-Aminobutyric Acid Aminotransferase by (1S,3S)-3-Amino-4-difluoromethylene-1-cyclopentanoic Acid (CPP-115) H Lee, EH Doud, R Wu, R Sanishvili, JI Juncosa, D Liu, NL Kelleher, ... Journal of the American Chemical Society 137 (7), 2628-2640, 2015 | 35 | 2015 |
A highly effective bifunctional ligand for radioimmunotherapy applications HS Chong, HA Song, CS Kang, T Le, X Sun, M Dadwal, H Lee, X Lan, ... Chemical communications 47 (19), 5584-5586, 2011 | 33 | 2011 |
Two continuous coupled assays for ornithine-δ-aminotransferase JI Juncosa, H Lee, RB Silverman Analytical biochemistry 440 (2), 145-149, 2013 | 23 | 2013 |
Visualizing reactive astrocyte-neuron interaction in Alzheimer’s disease using 11C-acetate and 18F-FDG MH Nam, HY Ko, D Kim, S Lee, YM Park, SJ Hyeon, W Won, JI Chung, ... Brain 146 (7), 2957-2974, 2023 | 17 | 2023 |
Analysis of plasma metabolic profiling and evaluation of the effect of the intake of Angelica keiskei using metabolomics and lipidomics HA Oh, H Lee, S Park, Y Lim, O Kwon, JY Kim, D Kim, BH Jung Journal of ethnopharmacology 243, 112058, 2019 | 17 | 2019 |
Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid H Lee, HV Le, R Wu, E Doud, R Sanishvili, JF Kellie, PD Compton, ... ACS chemical biology 10 (9), 2087-2098, 2015 | 17 | 2015 |
Deciphering fatty acid synthase inhibition-triggered metabolic flexibility in prostate cancer cells through untargeted metabolomics JE Oh, BH Jung, J Park, S Kang, H Lee Cells 9 (11), 2447, 2020 | 16 | 2020 |
Metabolite identification and pharmacokinetic profiling of PP242, an ATP-competitive inhibitor of mTOR using ultra high-performance liquid chromatography and mass spectrometry MM Rashid, H Lee, BH Jung Journal of Chromatography B 1072, 244-251, 2018 | 14 | 2018 |
Development of GC-MS based cytochrome P450 assay for the investigation of multi-herb interaction HA Oh, H Lee, D Kim, BH Jung Analytical biochemistry 519, 71-83, 2017 | 13 | 2017 |
LIN28A enhances regenerative capacity of human somatic tissue stem cells via metabolic and mitochondrial reprogramming K Pieknell, YA Sulistio, N Wulansari, WHW Darsono, MY Chang, JY Ko, ... Cell Death & Differentiation 29 (3), 540-555, 2022 | 12 | 2022 |
Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis W Won, HJ Choi, JY Yoo, D Kim, TY Kim, YH Ju, KD Park, H Lee, SY Jung, ... Experimental & Molecular Medicine 54 (8), 1188-1200, 2022 | 11 | 2022 |
Evaluation of the antitumor effects of PP242 in a colon cancer xenograft mouse model using comprehensive metabolomics and lipidomics MM Rashid, H Lee, BH Jung Scientific Reports 10 (1), 17523, 2020 | 11 | 2020 |