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Austin W.T. Chiang
Austin W.T. Chiang
Assistant Professor, IMMCG, Augusta university
augusta.edu의 이메일 확인됨
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The emerging role of systems biology for engineering protein production in CHO cells
CC Kuo, AWT Chiang, I Shamie, M Samoudi, JM Gutierrez, NE Lewis
Current opinion in biotechnology 51, 64-69, 2018
1042018
Multiplex secretome engineering enhances recombinant protein production and purity
S Kol, D Ley, T Wulff, M Decker, J Arnsdorf, S Schoffelen, AH Hansen, ...
Nature communications 11 (1), 1908, 2020
862020
Increasing consensus of context-specific metabolic models by integrating data-inferred cell functions
A Richelle, AWT Chiang, CC Kuo, NE Lewis
PLoS computational biology 15 (4), e1006867, 2019
712019
ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis
RJ Weiss, PN Spahn, AG Toledo, AWT Chiang, BP Kellman, J Li, ...
Proceedings of the National Academy of Sciences 117 (17), 9311-9317, 2020
432020
Elucidating Human Milk Oligosaccharide biosynthetic genes through network-based multi-omics integration
BP Kellman, A Richelle, JY Yang, D Chapla, AWT Chiang, JA Najera, ...
Nature Communications 13 (1), 2455, 2022
342022
Increased production of LIGHT by T cells in eosinophilic esophagitis promotes differentiation of esophageal fibroblasts toward an inflammatory phenotype
MC Manresa, AWT Chiang, RC Kurten, R Dohil, H Brickner, L Dohil, ...
Gastroenterology 159 (5), 1778-1792. e13, 2020
332020
Correcting for sparsity and interdependence in glycomics by accounting for glycan biosynthesis
B Bao, BP Kellman, AWT Chiang, Y Zhang, JT Sorrentino, AK York, ...
Nature Communications 12 (1), 1-14, 2021
32*2021
Non-protective immune imprint underlies failure of Staphylococcus aureus IsdB vaccine
CM Tsai, JR Caldera, IA Hajam, AWT Chiang, CH Tsai, H Li, ML Díez, ...
Cell host & microbe 30 (8), 1163-1172. e6, 2022
312022
Modulating carbohydrate–protein interactions through glycoengineering of monoclonal antibodies to impact cancer physiology
AWT Chiang, S Li, PN Spahn, A Richelle, CC Kuo, M Samoudi, NE Lewis
Current opinion in structural biology 40, 104-111, 2016
282016
Understanding system dynamics of an adaptive enzyme network from globally profiled kinetic parameters
AWT Chiang, WC Liu, P Charusanti, MJ Hwang
BMC systems biology 8 (1), 1-12, 2014
232014
Model-based assessment of mammalian cell metabolic functionalities using omics data
A Richelle, BP Kellman, AT Wenzel, AWT Chiang, T Reagan, ...
Cell Reports Methods 1 (3), 100040, 2021
222021
Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate
RJ Weiss, PN Spahn, AWT Chiang, Q Liu, J Li, KM Hamill, S Rother, ...
Nature Chemical Biology 17 (6), 684-692, 2021
202021
A Markov model of glycosylation elucidates isozyme specificity and glycosyltransferase interactions for glycoengineering
C Liang, AWT Chiang, AH Hansen, J Arnsdorf, S Schoffelen, ...
Current research in biotechnology 2, 22-36, 2020
202020
Combating viral contaminants in CHO cells by engineering innate immunity
AWT Chiang, S Li, BP Kellman, G Chattopadhyay, Y Zhang, CC Kuo, ...
Scientific reports 9 (1), 1-15, 2019
17*2019
A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis
LY Hsieh, AWT Chiang, LD Duong, CC Kuo, SX Dong, R Dohil, R Kurten, ...
Journal of Allergy and Clinical Immunology 148 (2), 486-494, 2021
162021
A consensus-based and readable extension of Linear Code for Reaction Rules (LiCoRR)
BP Kellman, Y Zhang, E Logomasini, E Meinhardt, KP Godinez-Macias, ...
Beilstein journal of organic chemistry 16 (1), 2645-2662, 2020
162020
Dysregulation of the secretory pathway connects Alzheimer’s disease genetics to aggregate formation
CC Kuo, AWT Chiang, HM Baghdassarian, NE Lewis
Cell Systems 12 (9), 873-884. e4, 2021
142021
Type 2 Immunity and Age Modify Gene Expression of Coronavirus-induced Disease 2019 Receptors in Eosinophilic Gastrointestinal Disorders
AWT Chiang, LD Duong, T Shoda, QM Nhu, M Ruffner, T Hara, B Aaron, ...
Journal of Pediatric Gastroenterology and Nutrition 72 (5), 718, 2021
132021
Artificial intelligence in the analysis of glycosylation data
H Li, AWT Chiang, NE Lewis
Biotechnology Advances 60, 108008, 2022
102022
What does your cell really do? Model-based assessment of mammalian cells metabolic functionalities using omics data
A Richelle, BP Kellman, AT Wenzel, AWT Chiang, T Reagan, ...
bioRxiv, 2020
92020
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