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Giuseppe Pignataro
Giuseppe Pignataro
Full Professor of Pharmacology, "Federico II" University of Naples, Italy
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Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions
L Annunziato, S Amoroso, A Pannaccione, M Cataldi, G Pignataro, ...
Toxicology letters 139 (2-3), 125-133, 2003
3562003
Pharmacology of brain Na+/Ca2+ exchanger: from molecular biology to therapeutic perspectives
L Annunziato, G Pignataro, GF Di Renzo
Pharmacological reviews 56 (4), 633-654, 2004
3502004
Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia
G Pignataro, RP Simon, ZG Xiong
Brain 130 (1), 151-158, 2007
3422007
In Vivo and In Vitro Characterization of a Novel Neuroprotective Strategy for Stroke: Ischemic Postconditioning
G Pignataro, R Meller, K Inoue, AN Ordonez, MD Ashley, X Zhigang, ...
Journal of Cerebral Blood Flow & Metabolism 28 (2), 232-241, 2008
2932008
Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases
ZG Xiong, G Pignataro, M Li, S Chang, RP Simon
Current opinion in pharmacology 8 (1), 25-32, 2008
2772008
Ischemic preconditioning regulates expression of microRNAs and a predicted target, MeCP2, in mouse cortex
TA Lusardi, CD Farr, CL Faulkner, G Pignataro, T Yang, J Lan, RP Simon, ...
Journal of Cerebral Blood Flow & Metabolism 30 (4), 744-756, 2010
2032010
Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia
G Pignataro, R Gala, O Cuomo, A Tortiglione, L Giaccio, P Castaldo, ...
Stroke 35 (11), 2566-2570, 2004
1972004
Rhythm-specific modulation of the sensorimotor network in drug-naive patients with Parkinson’s disease by levodopa
F Esposito, A Tessitore, A Giordano, R De Micco, A Paccone, R Conforti, ...
Brain 136 (3), 710-725, 2013
1942013
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage
P Molinaro, O Cuomo, G Pignataro, F Boscia, R Sirabella, A Pannaccione, ...
Journal of Neuroscience 28 (5), 1179-1184, 2008
1542008
Post‐ischemic brain damage: effect of ischemic preconditioning and postconditioning and identification of potential candidates for stroke therapy
G Pignataro, A Scorziello, G Di Renzo, L Annunziato
The FEBS journal 276 (1), 46-57, 2009
1352009
Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats
G Pignataro, A Tortiglione, A Scorziello, L Giaccio, A Secondo, B Severino, ...
Neuropharmacology 46 (3), 439-448, 2004
1222004
Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window
A Lanzillotta, G Pignataro, C Branca, O Cuomo, I Sarnico, M Benarese, ...
Neurobiology of disease 49, 177-189, 2013
1172013
Transgenic overexpression of adenosine kinase aggravates cell death in ischemia
G Pignataro, RP Simon, D Boison
Journal of Cerebral Blood Flow & Metabolism 27 (1), 1-5, 2007
1092007
Permanent Focal Brain Ischemia Induces Isoform-Dependent Changes in the Pattern of Na+/Ca2+ Exchanger Gene Expression in the Ischemic Core, Periinfarct …
F Boscia, R Gala, G Pignataro, A De Bartolomeis, M Cicale, ...
Journal of Cerebral Blood Flow & Metabolism 26 (4), 502-517, 2006
1072006
Ionic transporter activity in astrocytes, microglia, and oligodendrocytes during brain ischemia
L Annunziato, F Boscia, G Pignataro
Journal of Cerebral Blood Flow & Metabolism 33 (7), 969-982, 2013
1062013
HIF‐1α reveals a binding activity to the promoter of iNOS gene after permanent middle cerebral artery occlusion
C Matrone, G Pignataro, P Molinaro, C Irace, A Scorziello, GF Di Renzo, ...
Journal of neurochemistry 90 (2), 368-378, 2004
982004
Neuroprotective, immunosuppressant and antineoplastic properties of mTOR inhibitors: current and emerging therapeutic options
G Pignataro, D Capone, G Polichetti, A Vinciguerra, A Gentile, G Di Renzo, ...
Current opinion in pharmacology 11 (4), 378-394, 2011
922011
NCX1 is a novel target gene for hypoxia-inducible factor-1 in ischemic brain preconditioning
V Valsecchi, G Pignataro, A Del Prete, R Sirabella, C Matrone, F Boscia, ...
Stroke 42 (3), 754-763, 2011
912011
Downregulation of hippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism
G Pignataro, S Maysami, FE Studer, A Wilz, RP Simon, D Boison
Journal of Cerebral Blood Flow & Metabolism 28 (1), 17-23, 2008
872008
Sp3/REST/HDAC1/HDAC2 complex represses and Sp1/HIF-1/p300 complex activates ncx1 gene transcription, in brain ischemia and in ischemic brain preconditioning, by epigenetic …
L Formisano, N Guida, V Valsecchi, M Cantile, O Cuomo, A Vinciguerra, ...
Journal of Neuroscience 35 (19), 7332-7348, 2015
862015
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