Production of reactive oxygen species, alteration of cytosolic ascorbate peroxidase, and impairment of mitochondrial metabolism are early events in heat shock-induced … RA Vacca, MC de Pinto, D Valenti, S Passarella, E Marra, L De Gara Plant physiology 134 (3), 1100-1112, 2004 | 460 | 2004 |
Cytochrome c Is Released in a Reactive Oxygen Species-Dependent Manner and Is Degraded via Caspase-Like Proteases in Tobacco Bright-Yellow 2 Cells en … RA Vacca, D Valenti, A Bobba, RS Merafina, S Passarella, E Marra Plant physiology 141 (1), 208-219, 2006 | 229 | 2006 |
Mitochondrial dysfunction as a central actor in intellectual disability-related diseases: an overview of Down syndrome, autism, Fragile X and Rett syndrome D Valenti, L de Bari, B De Filippis, A Henrion-Caude, RA Vacca Neuroscience & Biobehavioral Reviews 46, 202-217, 2014 | 199 | 2014 |
Mitochondria and L-lactate metabolism S Passarella, L de Bari, D Valenti, R Pizzuto, G Paventi, A Atlante FEBS letters 582 (25-26), 3569-3576, 2008 | 178 | 2008 |
Mitochondrial respiratory chain Complexes I and IV are impaired by β-amyloid via direct interaction and through Complex I-dependent ROS production, respectively A Bobba, G Amadoro, D Valenti, V Corsetti, R Lassandro, A Atlante Mitochondrion 13 (4), 298-311, 2013 | 152 | 2013 |
Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome D Valenti, D De Rasmo, A Signorile, L Rossi, L de Bari, I Scala, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (4), 542-552, 2013 | 152 | 2013 |
Deficit of complex I activity in human skin fibroblasts with chromosome 21 trisomy and overproduction of reactive oxygen species by mitochondria: involvement of the cAMP/PKA … D Valenti, GA Manente, L Moro, E Marra, RA Vacca Biochemical Journal 435 (3), 679-688, 2011 | 150 | 2011 |
The polyphenols resveratrol and epigallocatechin-3-gallate restore the severe impairment of mitochondria in hippocampal progenitor cells from a Down syndrome mouse model D Valenti, L de Bari, D de Rasmo, A Signorile, A Henrion-Caude, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (6 …, 2016 | 129 | 2016 |
The riboflavin/FAD cycle in rat liver mitochondria M Barile, C Brizio, D Valenti, C De Virgilio, S Passarella European Journal of Biochemistry 267 (15), 4888-4900, 2000 | 112 | 2000 |
The role of mitochondrial transport in energy metabolism S Passarella, A Atlante, D Valenti, L de Bari Mitochondrion 2 (5), 319-343, 2003 | 111 | 2003 |
3′-Azido-3′-deoxythymidine uptake into isolated rat liver mitochondria and impairment of ADP/ATP translocator M Barile, D Valenti, S Passarella, E Quagliariello Biochemical pharmacology 53 (7), 913-920, 1997 | 108 | 1997 |
Mitochondria as pharmacological targets in Down syndrome D Valenti, N Braidy, D De Rasmo, A Signorile, L Rossi, AG Atanasov, ... Free Radical Biology and Medicine 114, 69-83, 2018 | 92 | 2018 |
Impairment of F1F0-ATPase, adenine nucleotide translocator and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with … D Valenti, A Tullo, MF Caratozzolo, RS Merafina, P Scartezzini, E Marra, ... Biochemical Journal 431 (2), 299-310, 2010 | 92 | 2010 |
Down syndrome: Neurobiological alterations and therapeutic targets RA Vacca, S Bawari, D Valenti, D Tewari, SF Nabavi, S Shirooie, AN Sah, ... Neuroscience & Biobehavioral Reviews 98, 234-255, 2019 | 87 | 2019 |
Mechanisms of toxicity of 3′-azido-3′-deoxythymidine: its interaction with adenylate kinase M Barile, D Valenti, GA Hobbs, MF Abruzzese, SA Keilbaugh, ... Biochemical pharmacology 48 (7), 1405-1412, 1994 | 87 | 1994 |
Mitochondria as cell targets of AZT (zidovudine) M Barile, D Valenti, E Quagliariello, S Passarella General Pharmacology: The Vascular System 31 (4), 531-538, 1998 | 86 | 1998 |
Mitochondrial free radical overproduction due to respiratory chain impairment in the brain of a mouse model of Rett syndrome: protective effect of CNF1 B De Filippis, D Valenti, L de Bari, D De Rasmo, M Musto, A Fabbri, ... Free Radical Biology and Medicine 83, 167-177, 2015 | 80 | 2015 |
Plant polyphenols as natural drugs for the management of Down syndrome and related disorders RA Vacca, D Valenti, S Caccamese, M Daglia, N Braidy, SM Nabavi Neuroscience & Biobehavioral Reviews 71, 865-877, 2016 | 77 | 2016 |
Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells D Valenti, L De Bari, GA Manente, L Rossi, L Mutti, L Moro, RA Vacca Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (12 …, 2013 | 71 | 2013 |
Mitochondria can cross cell boundaries: An overview of the biological relevance, pathophysiological implications and therapeutic perspectives of intercellular mitochondrial … D Valenti, RA Vacca, L Moro, A Atlante International journal of molecular sciences 22 (15), 8312, 2021 | 69 | 2021 |