Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease J Carmichael, J Chatellier, A Woolfson, C Milstein, AR Fersht, ... Proceedings of the National Academy of Sciences 97 (17), 9701-9705, 2000 | 268 | 2000 |
Structural and Functional Roles of Asparagine 175 in the Cysteine Protease Papain (∗) T Vernet, DC Tessier, J Chatellier, C Plouffe, TS Lee, DY Thomas, ... Journal of Biological Chemistry 270 (28), 16645-16652, 1995 | 204 | 1995 |
Measurement of antigen–antibody interactions with biosensors MHVV Regenmortel, D Altschuh, J Chatellier, L Christensen, ... Journal of Molecular Recognition: An Interdisciplinary Journal 11 (1‐6), 163-167, 1998 | 87 | 1998 |
In vivo activities of GroEL minichaperones J Chatellier, F Hill, PA Lund, AR Fersht Proceedings of the National Academy of Sciences 95 (17), 9861-9866, 1998 | 80 | 1998 |
Functional mapping of conserved residues located at the VL and VH domain interface of a Fab J Chatellier, MHV Van Regenmortel, T Vernet, D Altschuh Journal of molecular biology 264 (1), 1-6, 1996 | 71 | 1996 |
Minimal and optimal mechanisms for GroE-mediated protein folding AP Ben-Zvi, J Chatellier, AR Fersht, P Goloubinoff Proceedings of the National Academy of Sciences 95 (26), 15275-15280, 1998 | 62 | 1998 |
NMR analysis of the binding of a rhodanese peptide to a minichaperone in solution N Kobayashi, SMV Freund, J Chatellier, R Zahn, AR Fersht Journal of molecular biology 292 (1), 181-190, 1999 | 58 | 1999 |
GroEL recognises sequential and non-sequential linear structural motifs compatible with extended β-strands and α-helices J Chatellier, AM Buckle, AR Fersht Journal of molecular biology 292 (1), 163-172, 1999 | 57 | 1999 |
Effects on interaction kinetics of mutations at the VH–VL interface of Fabs depend on the structural context MB Khalifa, M Weidenhaupt, L Choulier, J Chatellier, N Rauffer‐Bruyère, ... Journal of Molecular Recognition 13 (3), 127-139, 2000 | 50 | 2000 |
Comparative interaction kinetics of two recombinant Fabs and of the corresponding antibodies directed to the coat protein of tobacco mosaic virus J Chatellier, N Rauffer‐Bruyère, MHV Van Regenmortel, D Altschuh, ... Journal of Molecular Recognition 9 (1), 39-51, 1996 | 43 | 1996 |
In vivo biotinylated recombinant antibodies: construction, characterization, and application of a bifunctional Fab-BCCP fusion protein produced in Escherichia coli E Weiss, J Chatellier, G Orfanoudakis Protein expression and purification 5 (5), 509-517, 1994 | 42 | 1994 |
From minichaperone to GroEL 3: properties of an active single-ring mutant of GroEL J Chatellier, F Hill, NW Foster, P Goloubinoff, AR Fersht Journal of Molecular Biology 304 (5), 897-910, 2000 | 38 | 2000 |
Expression of functional papain precursor in Saccharomyces cerevisiae: rapid screening of mutants T Vernet, J Chatellier, DC Tessier, DY Thomas Protein Engineering, Design and Selection 6 (2), 213-219, 1993 | 34 | 1993 |
The substrate binding domain of DnaK facilitates slow protein refolding N Tanaka, S Nakao, H Wadai, S Ikeda, J Chatellier, S Kunugi Proceedings of the National Academy of Sciences 99 (24), 15398-15403, 2002 | 31 | 2002 |
Cooperative effects of mutations in a recombinant Fab on the kinetics of antigen binding N Rauffer-Bruyère, J Chatellier, E Weiss, MHV van Regenmortel, ... Molecular immunology 34 (2), 165-173, 1997 | 30 | 1997 |
Interdomain interactions within the gene 3 protein of filamentous phage J Chatellier, O Hartley, AD Griffiths, AR Fersht, G Winter, L Riechmann FEBS letters 463 (3), 371-374, 1999 | 28 | 1999 |
From minichaperone to GroEL 2: importance of avidity of the multisite ring structure J Chatellier, F Hill, AR Fersht Journal of Molecular Biology 304 (5), 883-896, 2000 | 24 | 2000 |
Uses of biosensors in the study of viral antigens MHV Van Regenmortel, D Altschuh, J Chatellier, NR Bruyère, ... Immunological investigations 26 (1-2), 67-82, 1997 | 23 | 1997 |
Codon-based combinatorial alanine scanning site-directed mutagenesis: design, implementation, and polymerase chain reaction screening J Chatellier, A Mazza, R Brousseau, T Vernet Analytical biochemistry 229 (2), 282-290, 1995 | 22 | 1995 |
Protein scaffold and its use to multimerise monomeric polypeptides F Hill, J Chatellier, A Fersht US Patent App. 10/007,628, 2002 | 7 | 2002 |