| Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer Z Li, AC Bishop, M Alyamani, JA Garcia, R Dreicer, D Bunch, J Liu, ... Nature 523 (7560), 347-351, 2015 | 285 | 2015 |
| Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy Z Li, M Alyamani, J Li, K Rogacki, M Abazeed, SK Upadhyay, SP Balk, ... Nature 533 (7604), 547-551, 2016 | 167 | 2016 |
| Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer J Li, M Alyamani, A Zhang, KH Chang, M Berk, Z Li, Z Zhu, M Petro, ... Elife 6, e20183, 2017 | 97 | 2017 |
| Abiraterone acetate treatment lowers 11-oxygenated androgens C Wright, P O’Day, M Alyamani, N Sharifi, RJ Auchus European journal of endocrinology 182 (4), 413-421, 2020 | 52 | 2020 |
| HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer M Alyamani, H Emamekhoo, S Park, J Taylor, N Almassi, S Upadhyay, ... The Journal of clinical investigation 128 (8), 3333-3340, 2018 | 50 | 2018 |
| Steroidogenic metabolism of galeterone reveals a diversity of biochemical activities M Alyamani, Z Li, M Berk, J Li, J Tang, S Upadhyay, RJ Auchus, N Sharifi Cell chemical biology 24 (7), 825-832. e6, 2017 | 50 | 2017 |
| HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma J Zein, B Gaston, P Bazeley, MD DeBoer, RP Igo Jr, ER Bleecker, ... Proceedings of the National Academy of Sciences 117 (4), 2187-2193, 2020 | 35 | 2020 |
| Association of Tissue Abiraterone Levels and SLCO Genotype with Intraprostatic Steroids and Pathologic Response in Men with High-Risk Localized Prostate Cancer EA Mostaghel, E Cho, A Zhang, M Alyamani, A Kaipainen, S Green, ... Clinical Cancer Research 23 (16), 4592-4601, 2017 | 35 | 2017 |
| Development and validation of a novel LC–MS/MS method for simultaneous determination of abiraterone and its seven steroidal metabolites in human serum: Innovation in separation … M Alyamani, Z Li, SK Upadhyay, DJ Anderson, RJ Auchus, N Sharifi The Journal of steroid biochemistry and molecular biology 172, 231-239, 2017 | 31 | 2017 |
| Rapid and structure-specific cellular uptake of selected steroids JM McManus, K Bohn, M Alyamani, YM Chung, EA Klein, N Sharifi Plos one 14 (10), e0224081, 2019 | 26 | 2019 |
| Hexose-6-phosphate dehydrogenase blockade reverses prostate cancer drug resistance in xenograft models by glucocorticoid inactivation J Li, M Berk, M Alyamani, N Sabharwal, C Goins, J Alvarado, ... Science translational medicine 13 (595), eabe8226, 2021 | 22 | 2021 |
| Deep androgen receptor suppression in prostate cancer exploits sexually dimorphic renal expression for systemic glucocorticoid exposure M Alyamani, J Li, M Patel, S Taylor, F Nakamura, M Berk, C Przybycin, ... Annals of Oncology 31 (3), 369-376, 2020 | 22 | 2020 |
| High-dose abiraterone acetate in men with castration resistant prostate cancer TW Friedlander, JN Graff, K Zejnullahu, A Anantharaman, L Zhang, R Paz, ... Clinical Genitourinary Cancer 15 (6), 733-741. e1, 2017 | 21 | 2017 |
| AR Signaling in Prostate Cancer Regulates a Feed-Forward Mechanism of Androgen Synthesis by Way of HSD3B1 Upregulation D Hettel, A Zhang, M Alyamani, M Berk, N Sharifi Endocrinology 159 (8), 2884-2890, 2018 | 19 | 2018 |
| A PK/PD study of Delta-4 abiraterone metabolite in metastatic castration-resistant prostate cancer patients B Blanchet, E Carton, M Alyamani, L Golmard, O Huillard, ... Pharmacological Research 136, 56-61, 2018 | 10 | 2018 |
| Cancer-associated fibroblast-secreted glucosamine alters the androgen biosynthesis program in prostate cancer via HSD3B1 upregulation D Cui, J Li, Z Zhu, M Berk, A Hardaway, J McManus, YM Chung, ... The Journal of clinical investigation 133 (7), 2023 | 9 | 2023 |
| BMX controls 3βHSD1 and sex steroid biosynthesis in cancer X Li, M Berk, C Goins, M Alyamani, YM Chung, C Wang, M Patel, N Rathi, ... The Journal of clinical investigation 133 (2), 2023 | 8 | 2023 |
| HSD3B1 genotype and abiraterone (Abi) metabolites in patients (pts) with prostate cancer (PCa). H Emamekhoo, M Alyamani, S Park, J Taylor, N Almassi, S Upadhyay, ... Journal of Clinical Oncology 36 (6_suppl), 325-325, 2018 | 5 | 2018 |
| Elevated periprostatic venous testosterone correlates with prostate cancer progression after radical prostatectomy M Alyamani, P Michael, D Hettel, L Thomas, SD Lundy, M Berk, M Patel, ... Journal of Clinical Investigation 133 (17), e171117, 2023 | 2 | 2023 |
| ELEVATED PERIPROSTATIC VENOUS TESTOSTERONE CORRELATES WITH PROSTATE CANCER PROGRESSION AFTER RADICAL PROSTATECTOMY PD Michael, M Alyamani, D Hettel, L Thomas IV, S Lundy, M Berk, M Patel, ... Urologic Oncology: Seminars and Original Investigations 42, S89, 2024 | | 2024 |
Dr. Sunil K. UpadhyayThermo Fisher ScientificVerified email at thermofisher.com
