ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility G Zheng, JA Dahl, Y Niu, P Fedorcsak, CM Huang, CJ Li, CB Vågbø, ... Molecular cell 49 (1), 18-29, 2013 | 2937 | 2013 |
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation Y Yue, J Liu, X Cui, J Cao, G Luo, Z Zhang, T Cheng, M Gao, X Shu, H Ma, ... Cell discovery 4 (1), 10, 2018 | 764 | 2018 |
Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells D Han, J Liu, C Chen, L Dong, Y Liu, R Chang, X Huang, Y Liu, J Wang, ... Nature 566 (7743), 270-274, 2019 | 755 | 2019 |
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer J Liu, MA Eckert, BT Harada, SM Liu, Z Lu, K Yu, SM Tienda, ... Nature cell biology 20 (9), 1074-1083, 2018 | 639 | 2018 |
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally H Huang, H Weng, K Zhou, T Wu, BS Zhao, M Sun, Z Chen, X Deng, ... Nature 567 (7748), 414-419, 2019 | 501 | 2019 |
N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription J Liu, X Dou, C Chen, C Chen, C Liu, MM Xu, S Zhao, B Shen, Y Gao, ... Science 367 (6477), 580-586, 2020 | 456 | 2020 |
Unique features of the m6A methylome in Arabidopsis thaliana GZ Luo, A MacQueen, G Zheng, H Duan, LC Dore, Z Lu, J Liu, K Chen, ... Nature communications 5 (1), 5630, 2014 | 402 | 2014 |
YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma J Hou, H Zhang, J Liu, Z Zhao, J Wang, Z Lu, B Hu, J Zhou, Z Zhao, ... Molecular cancer 18, 1-17, 2019 | 247 | 2019 |
A genetically incorporated crosslinker reveals chaperone cooperation in acid resistance M Zhang, S Lin, X Song, J Liu, Y Fu, X Ge, X Fu, Z Chang, PR Chen Nature chemical biology 7 (10), 671-677, 2011 | 244 | 2011 |
Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis H Gan, L Wen, S Liao, X Lin, T Ma, J Liu, C Song, M Wang, C He, C Han, ... Nature communications 4 (1), 1995, 2013 | 202 | 2013 |
Structural insights into FTO’s catalytic mechanism for the demethylation of multiple RNA substrates X Zhang, LH Wei, Y Wang, Y Xiao, J Liu, W Zhang, N Yan, G Amu, X Tang, ... Proceedings of the National Academy of Sciences 116 (8), 2919-2924, 2019 | 193 | 2019 |
Regulation of gene expression by N6-methyladenosine in cancer J Liu, BT Harada, C He Trends in cell biology 29 (6), 487-499, 2019 | 178 | 2019 |
Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance Y Liu, G Liang, H Xu, W Dong, Z Dong, Z Qiu, Z Zhang, F Li, Y Huang, Y Li, ... Cell metabolism 33 (6), 1221-1233. e11, 2021 | 169 | 2021 |
Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer M Wang, J Liu, Y Zhao, R He, X Xu, X Guo, X Li, S Xu, J Miao, J Guo, ... Molecular cancer 19, 1-15, 2020 | 158 | 2020 |
The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth L Dong, C Chen, Y Zhang, P Guo, Z Wang, J Li, Y Liu, J Liu, R Chang, ... Cancer cell 39 (7), 945-957. e10, 2021 | 149 | 2021 |
Methylation modifications in eukaryotic messenger RNA J Liu, G Jia Journal of genetics and genomics 41 (1), 21-33, 2014 | 149 | 2014 |
Pooled CRISPR screening identifies m6A as a positive regulator of macrophage activation J Tong, X Wang, Y Liu, X Ren, A Wang, Z Chen, J Yao, K Mao, T Liu, ... Science advances 7 (18), eabd4742, 2021 | 118 | 2021 |
Nuclear m6A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos C Chen, W Liu, J Guo, Y Liu, X Liu, J Liu, X Dou, R Le, Y Huang, C Li, ... Protein & cell 12 (6), 455-474, 2021 | 94 | 2021 |
METTL14 is essential for β-cell survival and insulin secretion J Liu, G Luo, J Sun, L Men, H Ye, C He, D Ren Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (9 …, 2019 | 65 | 2019 |
Detailed modeling of positive selection improves detection of cancer driver genes S Zhao, J Liu, P Nanga, Y Liu, AE Cicek, N Knoblauch, C He, M Stephens, ... Nature communications 10 (1), 3399, 2019 | 59 | 2019 |